| Patent Number |
Title Of Patent |
Date Issued |
| RE38676 |
Thermally initiated polymerization of olefins using ruthenium or osmium vinylidene complexes |
December 21, 2004 |
| The present invention generally relates to the use of certain ruthenium and osmium complexes that are substantially inactive at a first temperature (preferably about room temperature) but becomes progressively more active at a higher second temperature. This difference in reactivities al |
| RE37194 |
High throughput solid phase chemical synthesis utilizing thin cylindrical reaction vessels useab |
May 29, 2001 |
| A high throughput chemical synthesis system utilizing cylindrical reaction vessels is disclosed. Reaction vessels are utilized which include a tubular member adapted for placement of electronically readable identifying indicia thereon. The identifying indicia are representative of re |
| 7598330 |
Cross-metathesis of olefins directly substituted with an electron-withdrawing group using transi |
October 6, 2009 |
| The invention pertains to the use of Group 8 transition metal alkylidene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand and at least one electron donor ligand in |
| 7560499 |
Initiator and ultraviolet absorber blends for changing lens power by ultraviolet light |
July 14, 2009 |
| Novel blends of photo-initiators and photo-absorbers are disclosed. By the proper selection of the type and amount of absorber and initiator used in a composition, it is possible to regulate the conditions under which photo-induced reactions occur. In a specific embodiment, blends of UV |
| 7550310 |
Techniques and systems for analyte detection |
June 23, 2009 |
| Techniques are used to detect and identify analytes. Techniques are used to fabricate and manufacture sensors to detect analytes. An analyte (810) is sensed by sensors (820) that output electrical signals in response to the analyte. The electrical signals may be preprocessed (830) by |
| 7507854 |
Impurity reduction in Olefin metathesis reactions |
March 24, 2009 |
| The present invention relates to the use of isomerization inhibitors in olefin metathesis reactions. The inhibitors are low molecular weight organic acids such as formic acid, acetic acid, benzoic acid, and the like. |
| 7381404 |
Treatment for dry macular degeneration |
June 3, 2008 |
| The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's m |
| 7329758 |
Imidazolidine-based metal carbene metathesis catalysts |
February 12, 2008 |
| The present invention relates to novel metathesis catalysts with an imidazolidine-based ligand and to methods for making and using the same. The inventive catalysts are of the formula ##STR00001## wherein: M is ruthenium or osmium; X and X.sup.1 are each independently an anionic l |
| 7288666 |
High metathesis activity ruthenium and osmium metal carbene complexes |
October 30, 2007 |
| Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The car |
| 7262315 |
Transition metal oxo, sulfido and amido complexes as catalysts of nucleophilic addition reaction |
August 28, 2007 |
| Methods are provided for carrying out nucleophilic addition reactions using oxo, sulfido or amido complexes of transition metals as reaction catalysts. Exemplary catalysts are oxo complexes of Group 7 transition metals, with rhenium (V) oxo complexes, including dioxo complexes, prefe |
| 7241009 |
Crosslinking of silicones presence of functionalized silicones |
July 10, 2007 |
| Methods and materials are disclosed for the production of optical elements, in particular intraocular lenses (IOL) that incorporate any amount (0 to 99%) of refraction and/or shape modulating compound into a substantially crosslinked first polymeric matrix. The materials produced acc |
| 7237893 |
Light adjustable lenses capable of post-fabrication power modification via multi-photon processe |
July 3, 2007 |
| The invention relates to novel photoinitiators and their use in light adjustable compositions. The initiatives comprise two or more multiphoton chromophores linked by a bridging compound. The bridging compound consists of a material that is compatible with the base material of the li |
| 7229634 |
Engineered proteins, and methods of making and using |
June 12, 2007 |
| The present invention provides engineered proteins and biomedical products made from the engineered proteins. The biomedical products include lenses useful for ophthalmic purposes. |
| 7210783 |
Lenses capable of post-fabrication power modification |
May 1, 2007 |
| The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. Wh |
| 7175885 |
Compositionally different polymer-based sensor elements and methods for preparing same |
February 13, 2007 |
| The present invention provides a combinatorial approach for preparing arrays of chemically sensitive polymer-based sensors which are capable of detecting the presence of a chemical analyte in a fluid in contact therewith. The described methods and devices comprise combining varying r |
| 7134755 |
Customized lenses |
November 14, 2006 |
| The invention relates to a method of customizing lenses using an external stimulus such as light. Fine-tuning of the lens to match the precise optical requirements using the same lens is also possible. The lenses are self-contained and do not require the addition or removal of significan |
| 7102047 |
High metathesis activity ruthenium and osmium metal carbene complexes |
September 5, 2006 |
| Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The car |
| 7074840 |
Light adjustable lenses capable of post-fabrication power modification via multi-photon processe |
July 11, 2006 |
| The invention relates to novel photoinitiators and their use in light adjustable compositions. The initiatives comprise two or more multiphoton chromophores linked by a bridging compound. The bridging compound consists of a material that is compatible with the base material of the li |
| 7061061 |
Techniques and systems for analyte detection |
June 13, 2006 |
| Techniques are used to detect and identify analytes. Techniques are used to fabricate and manufacture sensors to detect analytes. An analyte (810) is sensed by sensors (820) that output electrical signals in response to the analyte. The electrical signals may be preprocessed (830) by |
| 7034096 |
Ring-expansion of cyclic olefins metathesis reactions with an acyclic diene |
April 25, 2006 |
| This invention relates generally to synthetic procedures that include the step of ring-opening metathesis of cyclic olefins and reaction with an acyclic diene co-reactant to produce olefin macrocycles by ring expansion, or alternatively. The ring expansion of the cyclic olefin is pro |
| 7022789 |
Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same |
April 4, 2006 |
| The present invention relates to telechelic polymers having crosslinkable end groups of the formula ##STR00001## and methods for preparing the same wherein n is an integer; ##STR00002## is an alkadienyl group; Y is an alkyl group; and Z is crosslinkable end group. In general, the |
| 6987154 |
Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olef |
January 17, 2006 |
| This invention relates generally to synthetic procedures that include the step of ring-opening metathesis of cyclic olefins and reaction with an acyclic diene co-reactant to produce regularly repeating A,B-alternating olefin polymers. The A,B-alternating polymers are produced by varying |
| 6890715 |
Sensors of conducting and insulating composites |
May 10, 2005 |
| The present invention provides a class of sensors prepared from at least a first material having a positive temperature coefficient of resistance and a second non-conductive or insulating material compositionally different than the first material that show an increase sensitivity detecti |
| 6884859 |
Ring-opening metathesis polymerization of bridged bicyclic and polycyclic olefins containing two |
April 26, 2005 |
| A method is provided for synthesizing a polymer in a controlled fashion using a ring-opening metathesis polymerization (ROMP) reaction, wherein polymerization is carried out using a catalytically effective amount of an olefin metathesis catalyst and a bridged bicyclic or polycyclic olefi |
| 6867274 |
Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same |
March 15, 2005 |
| The present invention relates to telechelic polymers having crosslinkable end groups of the formula ##STR1##and methods for preparing the same wherein n is an integer; ##STR2##is an alkadienyl group; Y is an alkyl group; and Z is crosslinkable end group. In general, the inventive syn |
| 6838489 |
High activity metal carbene metathesis catalysts generated using a thermally activated N-heteroc |
January 4, 2005 |
| The invention provides a method for converting a less active or slower to initiate system to a higher activity system so that at the end of a polymerization the most active species is present in the system. The invention generally relates to a process for converting a less active or |
| 6824266 |
Lenses capable of post-fabrication power modification |
November 30, 2004 |
| The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. Wh |
| 6818586 |
Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts |
November 16, 2004 |
| The present invention relates to novel hexacoordinated metathesis catalysts and to methods for making and using the same. The inventive catalysts are of the formula ##STR1##wherein: M is ruthenium or osmium; X and X.sup.1 are the same or different and are each independently an |
| 6813097 |
Lenses capable of post-fabrication modulus change |
November 2, 2004 |
| Novel optical elements are provided which are capable of post fabrication modifications. Specifically, the invention includes lenses, such as intraocular lens, which can undergo changes in storage modulus after fabrication. |
| 6806325 |
High metathesis activity ruthenium and osmium metal carbene complexes |
October 19, 2004 |
| Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The carbene |
| 6803429 |
Selective ring-opening cross-metathesis of cycloolefins |
October 12, 2004 |
| A catalytic method is provided for a ring-opening cross-metathesis reaction between a cycloolefinic substrate and a second olefinic reactant, wherein the catalyst used is a transition metal alkylidene complex substituted with an N-heterocyclic carbene ligand. The substrates are selected |
| 6794534 |
Synthesis of functionalized and unfunctionalized olefins via cross and ring-closing metathesis |
September 21, 2004 |
| The invention is directed to the cross-metathesis and ring-closing metathesis reactions between geminal disubstituted olefins and terminal olefins, wherein the reaction employs a Ruthenium or Osmium metal carbene complex. Specifically, the invention relates to the synthesis of .alpha |
| 6759537 |
Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts |
July 6, 2004 |
| The present invention relates to novel hexacoordinated metathesis catalysts and to methods for making and using the same. The inventive catalysts are of the formula ##STR1##wherein: M is ruthenium or osmium; X and X.sup.1 are the same or different and are each independently an |
| 6752964 |
Polymer/plasticizer based sensors |
June 22, 2004 |
| This invention relates to a novel class of vapor sensors with tunable properties. More particularly, this invention relates to vapor sensors modified by the addition of a compatible small molecule of low volatility, i.e., a plasticizer. In certain aspects, the invention relates to a sens |
| 6749632 |
Application of wavefront sensor to lenses capable of post-fabrication power modification |
June 15, 2004 |
| The present invention relates to methods of implementing an optical element having a refraction modulating composition. The methods include using a wavefront sensor to provide an optical measurement of the optical element. The present invention also relates to systems comprising an optic |
| 6696597 |
Metathesis syntheses of pheromones or their components |
February 24, 2004 |
| The present invention relates to metathesis syntheses for insect sex-attractant pheromones or their components, such as E-5-decenyl acetate, the major component of the Peach Twig Borer pheromone; (5R,6S)-6-acetoxy-5-hexadecanolide, the mosquito oviposition attractant pheromone; E9,Z1 |
| 6696536 |
ABA triblock and diblock copolymers and methods of preparing the same |
February 24, 2004 |
| The invention discloses a method for preparing a triblock copolymer of the formula: ##STR1##comprising: (a) contacting a cycloalkene with a chain transfer agent of the formula:wherein n and m are integers; Z is an ATRP initiator and --Y.dbd.Y-- is an alkenyl group; and, R' is selected |
| 6624265 |
Ruthenium metal alkylidene complexes coordinated with triazolylidene ligands that exhibit high o |
September 23, 2003 |
| The invention discloses ruthenium alkylidene complexes of the type (PCy.sub.3)(L)Cl.sub.2 Ru(CHPh), where L is a triazolylidene ligand of the general formula: ##STR1##These catalysts have been found to be considerably more active for olefin metathesis at elevated temperatures than th |
| 6613910 |
One-pot synthesis of group 8 transition metal carbene complexes useful as olefin metathesis cata |
September 2, 2003 |
| The invention provides a novel method for synthesizing transition metal carbene complexes useful as olefin metathesis catalysts. The method is a convenient one-pot synthesis in which transition metal carbenes are prepared in high yield from readily available starting materials via a |
| 6610626 |
Highly active metathesis catalysts generated in situ from inexpensive and air stable precursors |
August 26, 2003 |
| The invention provides a process for the in-situ generation of a metathesis active catalyst of the formula: ##STR1##comprising contacting an NHC carbene with a dimer of the formula [(arene)MX.sup.1 X].sub.2 and an ##STR2##alkyne of the formula RC.ident.CR.sup.1 or wherein M is rut |
| 6515084 |
High metathesis activity ruthenium and osmium metal carbene complexes |
February 4, 2003 |
| Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The carbene |
| 6504041 |
Synthesis of ruthenium or osmium metathesis catalysts |
January 7, 2003 |
| The present invention relates to the synthesis of highly active ruthenium and osmium carbene metathesis catalyst in good yield from readily available starting materials. The catalysts that may be synthesized are of the general formula ##STR1##wherein: M is ruthenium or osmium; |
| 6495892 |
Techniques and systems for analyte detection |
December 17, 2002 |
| Techniques are used to detect and identify analytes. Techniques are used to fabricate and manufacture sensors to detect analytes. An analyte (810) is sensed by sensors (820) that output electrical signals in response to the analyte. The electrical signals may be preprocessed (830) by fil |
| 6486279 |
Acid activation of ruthenium metathesis catalysts and living ROMP metathesis polymerization in w |
November 26, 2002 |
| Activation of ruthenium based catalyst compounds with acid to improve reaction rates and yields of olefin metathesis reactions, including ROMP, RCM, ADMET and cross-methasis reactions is disclosed. The ruthenium catalyst compounds are ruthenium carbene complexes of the general formula |
| 6482908 |
Template-directed ring-closing metathesis and ring-opening metathesis polymerization of function |
November 19, 2002 |
| Functionalized cyclic olefins and methods for making the same are disclosed. Methods include template-directed ring-closing metathesis ("RCM") of functionalized acyclic dienes and template-directed depolymerization of functionalized polymers possessing regularly spaced sties of unsat |
| 6465590 |
Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same |
October 15, 2002 |
| The present invention relates to telechelic polymers having crosslinkable end groups of the formula ##STR1##and methods for preparing the same wherein n is an integer; ##STR2##is an alkadienyl group; Y is an alkyl group; and Z is crosslinkable end group. In general, the inventive syn |
| 6450642 |
Lenses capable of post-fabrication power modification |
September 17, 2002 |
| The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. Wh |
| 6433101 |
Fluorinated polymers and methods for their preparation |
August 13, 2002 |
| The present invention relates to the post-polymerization fluorination methods of polymers produced via ring-opening metathesis polymerization. Unlike prior art methods that result in low product yields and generally involve chemically aggressive reagents, the inventive methods produce |
| 6426419 |
Ruthenium metal alkylidene complexes coordinated with triazolylidene ligands that exhibit high o |
July 30, 2002 |
| The invention discloses ruthenium alkylidene complexes of the type (PCy.sub.3)(L)Cl.sub.2 Ru(CHPh), where L is a triazolylidene ligand of the general formula: ##STR1##These catalysts have been found to be considerably more active for olefin metathesis at elevated temperatures than th |
| 6414097 |
Methods for cross-methathesis of terminal olefins |
July 2, 2002 |
| A method for the cross-metathesis of terminal olefins is disclosed. The method describes making disubstituted internal olefin products by contacting a first terminal olefin with another first terminal olefin to form a dimer and then contacting the dimer with a second terminal olefin |
