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Richard Axel Patents
Inventor:
Axel; Richard
Address:
NY, NY
No. of patents:
18
Patents:












Patent Number Title Of Patent Date Issued
8017398 Method for assaying protein-protein interaction September 13, 2011
The invention relates to a method for determining if a test compound, or a mix of compounds, modulates the interaction between two proteins of interest. The determination is made possible via the use of two recombinant molecules, one of which contains the first protein a cleavage sit
7241881 Genes encoding insect odorant receptors and uses thereof July 10, 2007
This invention provides an isolated nucleic acid molecule encoding an insect odorant receptor. This invention provides a nucleic acid molecule of at least 12 nucleotides capable of specifically hybridizing with the nucleic acid molecule encoding an insect odorant receptor. This invention
7049076 Method for assaying protein--protein interaction May 23, 2006
The invention relates to a method for determining if a test compound, or a mix of compounds, modulates the interaction between two proteins of interest. The determination is made possible via the use of two recombinant molecules, one of which contains the first protein a cleavage sit
6673896 Derivatives of soluble T-4 January 6, 2004
This invention provides a therapeutic agent capable of specifically forming a complex with human immunodeficiency virus envelope glycoprotein which comprises a polypeptide. In one embodiment of the invention, the amino acid sequence of the polypeptide comprises the amino acid sequence sh
6570000 DNA encoding the T cell surface protein CD4 and use of fragments of CD4 in the treatment of AIDS May 27, 2003
A single-stranded nucleic acid molecule which encodes an amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject
6455275 DNA construct for producing proteinaceous materials in eucaryotic cells September 24, 2002
The invention relates to processes for inserting into eucaryotic cells a multiplicity of DNA molecules which includes genes coding for desired proteinaceous materials. The insertion of multiple copies of desired genes is accomplished by cotransformation with the desired genes and with
6093539 DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS July 25, 2000
This invention provides an isolated single-stranded nucleic acid which encodes an aqueous-soluble polypeptide comprising at least a portion of a human T4 glycoprotein, which portion specifically forms a complex with a human immunodeficiency virus envelope glycoprotein.
5958678 DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS September 28, 1999
A single-stranded nucleic acid molecule which encodes an amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject
5871913 DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS February 16, 1999
A single-stranded nucleic acid molecule which encodes the amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject
5422274 Internal deletion mutants of soluble T4(CD4) June 6, 1995
This invention provides a therapeutic agent capable of specifically forming a complex with human immunodeficiency virus envelope glycoprotein which comprises a polypeptide. In one embodiment of the invention, the amino acid sequence of the polypeptide has the amino acid sequence shown in
5179017 Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials January 12, 1993
The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is accomplished by cotransforming
5149636 Method for introducing cloned, amplifiable genes into eucaryotic cells and for producing protein September 22, 1992
Multiple copies of a foreign DNA I coding for the production of a protein may be introduced into eucaryotic cells by cotransforming suitable cells with foreign DNA I and with foreign DNA II which includes a functionally deficient, amplifiable gene coding for a selectable or identifiable
5126433 Soluble forms of the T cell surface protein CD4 June 30, 1992
A single-stranded nucleic acid molecule which encodes an amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject
5110906 Derivatives of soluble T-4 May 5, 1992
This invention provides a therapeutic agent capable of specifically forming a complex with human immunodeficiency virus envelope glycoprotein which comprises a polypeptide. In one embodiment of the invention, the amino acid sequence of the polypeptide comprises the amino acid sequence sh
4985352 DNA encoding serotonin 1C (5HT1c) receptor, isolated 5HT1c receptor, mammalian cells expressing January 15, 1991
The invention relates to DNA encoding a functional serotonin 5HT1c receptor, e.g., cDNA, and to the isolated, functional serotonin 5HT1c receptor encoded by such DNA. The invention also relates to mammalian cells expressing the cDNA encoding the 5HT1c receptor and to a DNA probe usef
4839293 DNA encoding streptavidin, streptavidin produced therefrom, fused polypeptides which include ami June 13, 1989
DNA which encodes the polypeptide streptavidin has been isolated as a fragment 2 kb in length derived from a restriction endonuclease digestion of the chromosomal DNA of Streptomyces avidinii. The nucleic acid sequence of the gene and the amino acid sequence of the polypeptide have been
4634665 Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials January 6, 1987
The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is accomplished by cotransforming
4399216 Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials August 16, 1983
The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is accomplished by cotransforming










 
 
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