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Daniel A. Vallera Patents
Inventor:
Vallera; Daniel A.
Address:
St. Louis Park, MN
No. of patents:
5
Patents:




Patent Number Title Of Patent Date Issued
7101542 Cell-mediated targeting of toxins to pathogenic cells September 5, 2006
The invention features vectors encoding immunotoxic fusion proteins containing targeting domains and toxic domains, targeting cells transduced with the vectors, methods of making the targeting cells, and methods of treating diseases (e.g., cancer) using both the vectors and the trans
6846484 DTAT fusion toxin January 25, 2005
The invention provides fusion toxins that contain one or more regions of diphtheria toxin and a portion of urokinase-type plasminogen activator, as well as the nucleic acids that encode the fusion toxins and methods of using the fusion toxins.
6492498 Multimeric immunotoxins December 10, 2002
The invention features fusion protein monomers, multimeric immunotoxic proteins, nucleic acids encoding fusion protein monomers, vectors containing the nucleic acids, and cells containing the vectors. Also encompassed by the invention are methods of killing pathogenic cells and makin
6001329 Radiolabeled fusion toxins for cancer therapy December 14, 1999
The present invention provides the synthesis and purification of a new class of compounds known as radiolabeled fusion toxins (RFT), in which both toxin and radionuclide tags are contained on the same growth factor, for example, murine granulocyte macrophage colony stimulating factor,
4831122 Radioimmunotoxins May 16, 1989
Radioimmunotoxins consisting of a monoclonal antibody covalently coupled to a toxin and a radionuclide. The compositions retain high binding specificity and cytotoxic activity and are useful in treating cancer and in bone marrow transplantation. The antibody component determines the


 
 
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