| Patent Number |
Title Of Patent |
Date Issued |
| 7375204 |
Fungal cell wall synthesis gene |
May 20, 2008 |
| A reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered. Further, fungal genes conferring resistance to the above compounds were identified and methods of screening |
| 6787534 |
Sulfonamide-containing heterocyclic compounds |
September 7, 2004 |
| The present invention provides a sulfonamide- or sulfonylurea-containing heterocyclic compounds. Specifically, it provides a heterocyclic compound represented by the formula (I), a pharmacologically acceptable salt thereof or a hydrate of them. ##STR1##In the formula, A is hydrogen a |
| 6673787 |
Sulfonamide-containing indole compounds |
January 6, 2004 |
| The present invention creates a novel antiangiogenic agent and provides an antitumor agent which shows high safety as compared with conventional antitumor agents, has a sure effect and is able to be administered for a long period. That is, it provides an indole compound represented by th |
| 6638964 |
Sulfonamide-containing indole compounds |
October 28, 2003 |
| The present invention creates a novel antiangiogenic agent and provides an antitumor agent which shows high safety as compared with conventional antitumor agents, has a sure effect and is able to be administered for a long period. That is, it provides an indole compound represented by th |
| 6469043 |
Sulfonamide-containing indole compounds |
October 22, 2002 |
| The present invention creates a novel antiangiogenic agent and provides an antitumor agent which shows high safety as compared with conventional antitumor agents, has a sure effect and is able to be administered for a long period. That is, it provides an indole compound represented by th |
| 5998445 |
Pyridine derivatives having anti-ulcerative activity |
December 7, 1999 |
| Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are described. |
| 5854274 |
Tricyclic heterocyclic sulfonamide and sulfonic ester derivatives |
December 29, 1998 |
| Novel tricyclic heterocyclic sulfonamide derivatives and sulfonic ester derivatives which have excellent antitumor activity and are represented by the following general formula (I) and processes for producing the same are provided. The present sulfonamide derivatives or a sulfonic ester |
| 5846969 |
Tricyclic heterocyclic sulfonamide and sulfonic ester derivatives |
December 8, 1998 |
| A sulfonamide derivative or a sulfonic ester derivative represented by the following general formula (I): ##STR1## {G represents an aromatic 5- or 6-membered ring; L represents O or --N(R.sup.1)-- (R.sup.1 represents hydrogen or lower alkyl); and M represents ##STR2## rin |
| 5840910 |
Pyridine derivatives having anti-ulcerative activity |
November 24, 1998 |
| Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are disclosed. |
| 5834462 |
Tricyclic heterocyclic sulfonamide and sulfonic ester derivatives |
November 10, 1998 |
| Novel tricyclic heterocyclic sulfonamide derivatives and sulfonic ester derivatives which have each an antitumor action and are represented by the following general formula (I) and processes for producing the same are provided. These compounds have each an excellent antitumor activity.A |
| 5708013 |
Pyridine derivative and therapeutic agent for ulcer comprising the same |
January 13, 1998 |
| A pyridine compound having the formula is disclosed and useful to treat the peptic ulcer. ##STR1## wherein R.sup.1 and R.sup.2 which may be the same or different are each a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogenated lower alkyl group, or a halogen ato |
| 5688800 |
Condensed pyrimidine derivative |
November 18, 1997 |
| A novel pyrimidine derivative having an excellent antitumor activity, which is represented by the following general formula (I) or a pharmacologically acceptable salt thereof: ##STR1## wherein R.sup.1 represents a hydroxyl or amino group;R.sup.2 represents a phenylene, pyridinediyl, |
| 5610320 |
Sulfonamide phenyl substituted compounds |
March 11, 1997 |
| Sulfonamide compounds of the formula or pharmacologically acceptable salts thereof: ##STR1## wherein: R.sup.1 is a hydrogen atom, halogen atom, lower alkyl group, lower alkoxy group, hydroxyl group, nitro group, phenoxy group, cyano group, acetyl group, amino group or a protected |
| 5610304 |
Pyrimidinyl or pyridinyl sulfonamide substituted compounds |
March 11, 1997 |
| Sulfonamide compounds of formula (I) or a pharmacologically acceptable salt thereof: ##STR1## exhibit excellent antitumor activity and low toxicity. |
| 5554615 |
Condensed pyrimidine derivative |
September 10, 1996 |
| A novel pyrimidine derivative having an excellent antitumor activity, which is represented by the following general formula (I) or a pharmacologically acceptable salt thereof: ##STR1## wherein R.sup.1 represents a hydroxyl or amino group; R.sup.2 represents a phenylene, pyridined |
| 5434172 |
Sulfonamide derivatives |
July 18, 1995 |
| Sulfonamide derivatives of the general formula (I): ##STR1## wherein preferably R.sup.1 represents a lower alkoxy group, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower |
| 5332751 |
Pyridine carboxamide compounds which have useful as pharmaceutical utility |
July 26, 1994 |
| Sulfonamide derivatives of the general formula (I): ##STR1## wherein preferably R.sup.1 represents a lower alkoxy group, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower |
| 5292758 |
Sulfonamide derivatives |
March 8, 1994 |
| Sulfonamide derivatives of the general formula (I): ##STR1## wherein preferably R.sup.1 represents a lower alkoxy group, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower |
| 5250549 |
Sulfonamide derivatives |
October 5, 1993 |
| Sulfonamide derivatives of the general formula (I): ##STR1## wherein preferably R.sup.1 represents a lower alkoxy group, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are as defined in the specification, A and B may be the same or different from each other and each repr |
| 5239079 |
Pyridinium salt and pharmacological composition containing the same |
August 24, 1993 |
| A pyridinium salt is useful as an antiulcer and is defined by the following formula. It includes a sulphenamide compound and a pyridinium compound. J is benzoimidazole, K is --S-- or --SSR, Z is hydroxy or oxyalkyl. ##STR1## |
| 5162317 |
Pyridinium salt and pharmacological composition containing the same |
November 10, 1992 |
| A pyridinium salt useful as an antiulcer agent, defined by formula (I) is disclosed. It includes a sulphenamide compound and a pyridinium compound. J is benzimidazole, K is --S-- or --SSR-- and Z is hydroxy or alkoxy. ##STR1## |
| 5075335 |
Guanidinobenzoic ester derivative |
December 24, 1991 |
| A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: |
| 5045552 |
Pyridine derivatives having anti-ulcerative activity |
September 3, 1991 |
| Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are described. |
| 4948808 |
Guanidinobenzoic ester derivative |
August 14, 1990 |
| A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: |
| 4801603 |
Guanidinobenzoic ester derivative |
January 31, 1989 |
| A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: |
| 4370005 |
Device for preventing tubular bushing assembly from slipping out |
January 25, 1983 |
| A device for preventing a tubular bushing assembly from slipping out of a hole in a bushing receiving portion, wherein the tubular bushing assembly is incorporated in a pivot coupling portion between two members, and includes an inner sleeve, a resilient member and an outer sleeve, the |
