| Patent Number |
Title Of Patent |
Date Issued |
| 7354992 |
Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and us |
April 8, 2008 |
| The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention. |
| 7335467 |
Breast cancer antigens |
February 26, 2008 |
| The invention provides methods for diagnosing cancer including breast cancer, based on the identification of certain breast cancer-associated polypeptides as antigens that elicit immune responses in breast cancer. The identified antigens can be utilized as markers for diagnosing breast |
| 7314721 |
Small cell lung cancer associated antigens and uses therefor |
January 1, 2008 |
| Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in small cell lung cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated an |
| 7291335 |
Isolated nucleic acid molecules encoding ESO-1 peptides and uses thereof |
November 6, 2007 |
| The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also des |
| 6982316 |
Isolated nucleic acid molecules associated with colon cancer and methods for diagnosing and trea |
January 3, 2006 |
| Various molecules associated with disorders such as cancer are disclosed. The invention also discloses diagnostic aid therapeutic methods based upon these molecules, as well as compositions for stimulating an immune response and methods for identifying cancer-associated nucleic acid and |
| 6830924 |
Isolated nucleic acid molecule encoding cancer associated antigens, the antigens per se, and use |
December 14, 2004 |
| The invention relates to newly identified cancer associated antigens, referred to as CT7, KOC-2 and KOC-3. The invention also relates to observations regarding known molecule KOC-1. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. T |
| 6794501 |
Colon cancer antigen panel |
September 21, 2004 |
| The invention provides methods for diagnosing cancer including colon cancer, based on the identification of certain colon cancer-associated polypeptides as antigens that elicit immune responses in colon cancer. The identified antigens can be utilized as markers for diagnosing colon c |
| 6576756 |
Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses |
June 10, 2003 |
| The invention relates to the isolation of a nucleic acid molecule which encodes a cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen, and peptides derived from it. |
| 6525177 |
Truncated forms of NY-ESO-1 protein |
February 25, 2003 |
| The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also des |
| 6518415 |
Recombinant human anti-Lewis Y antibodies |
February 11, 2003 |
| The invention provides for the production of several humanized murine antibodies specific for the antigen Lewis Y, which is recognized by the murine antibody Lewis Y. The Lewis Y antigen is expressed in normal tissues but the level of expression is higher in certain tumor types so th |
| 6517837 |
Isolated nucleic acid molecules associated with colon cancer and methods for diagnosing and trea |
February 11, 2003 |
| Various molecules associated with disorders such as cancer are disclosed. The invention also discloses diagnostic and therapeutic methods based upon these molecules, as well as compositions for stimulating an immune response and methods for identifying cancer-associated nucleic acid and |
| 6440663 |
Renal cancer associated antigens and uses therefor |
August 27, 2002 |
| Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in renal cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens exp |
| 6403373 |
Isolated nucleic acid molecules associated with colon, renal, and stomach cancer and methods of |
June 11, 2002 |
| Various molecules associated with cancer are disclosed. The invention also discloses diagnostic and therapeutic methods based upon these molecules. |
| 6310185 |
Recombinant human anti-Lewis Y antibodies |
October 30, 2001 |
| The invention provides for the production of several humanized murine antibodies specific for the antigen Lewis Y, which is recognized by murine atibodies specific for the Lewis Y antigen. The Lewis Y antigen is expressed in normal tissues but the level of expression is higher in cer |
| 6297364 |
Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses |
October 2, 2001 |
| The invention relates to the isolation of a nucleic acid molecule which encodes a cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen, and peptides derived from it. |
| 6252052 |
Antibodies which bind to NY-ESO-1 cancer associated proteins, and hybridomas which produce these |
June 26, 2001 |
| The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also des |
| 6251603 |
Method for determining status of a cancerous condition by determining antibodies to NY-ESO-1 in |
June 26, 2001 |
| The invention relates to methods for determining tumor status by determining antibodies specific to NY-ESO-1 in patient samples. One can determine whether a cancerous condition is progressing, regressing, or remaining stable by determining antibodies against NY-ESO-1 in a patient sam |
| 6043084 |
Isolated nucleic acid molecules associated with colon cancer and methods for diagnosing and trea |
March 28, 2000 |
| Various molecules associated with disorders such as colon cancer are disclosed. The invention also discloses diagnostic and therapeutic methods based upon these molecules. |
| 5874060 |
Recombinant human anti-Lewis Y antibodies |
February 23, 1999 |
| The invention provides for the production of several humanized murine antibodies specific for the antigen Lewis Y, which is recognized by the murine antibody Lewis Y. The Lewis Y antigen is expressed in normal tissues but the level of expression is higher in certain tumor types so th |
| 5843448 |
Tumor rejection antigen precursor |
December 1, 1998 |
| The invention relates to monoclonal antibodies which specifically bind to the tumor rejection antigen precursor molecule MAGE-1, hybridomas which produce these monoclonal antibodies, and their use. Also described is a recombinant form of MAGE-1, peptides which are useful as immunogens, a |
| 5674749 |
Monoclonal antibodies which bind to tumor rejection antigen precursor melan-A, and uses thereof |
October 7, 1997 |
| The invention relates to monoclonal antibodies which specifically bind to the tumor rejection antigen precursor molecule Melan-A, hybridomas which produce these monoclonal antibodies, and their use. Also described is a recombinant form of Melan-A and immunogenic compositions containing t |
| 5618534 |
Isolated antigen endo glyx-1 |
April 8, 1997 |
| An antigen which is specific to vascular endothelium is described. Described is a cell surface antigen which consists of four subunits; of 190, 145, 125 and 110 kd as determined by SDS-PAGE under reducing conditions as is a monoclonal antibody specific to this antigen. Uses, both dia |
| 5541104 |
Monoclonal antibodies which bind to tumor rejection antigen precursor mage-1 |
July 30, 1996 |
| The invention relates to monoclonal antibodies which specifically bind to the tumor rejection antigen precursor molecule MAGE-1, hybridomas which produce these monoclonal antibodies, and their use. Also described is a recombinant form of MAGE-1, peptides which are useful as immunogens, a |
| 5536641 |
Monoclonal antibody specific for vascular endothelial cell antigen endoglyx-1 and uses thereof f |
July 16, 1996 |
| An antigen which is specific to vascular endothelium is described. Described is a cell surface antigen which consists of four subunits, of 190, 145, 125 and 110 kd as determined by SDS-PAGE under reducing conditions as is a monoclonal antibody specific to this antigen. Uses, both dia |
