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George Sachs Patents
Inventor:
Sachs; George
Address:
Encino, CA
No. of patents:
16
Patents:




Patent Number Title Of Patent Date Issued
7276473 Methods and compositions for the treatment of pancreatitis October 2, 2007
Methods and compositions for the treatment of acute pancreatitis in a mammal. Particular compositions comprise a binding element, a translocation element, and a therapeutic element able to prevent accumulation of digestive enzymes within the pancreas.
6897227 Prodrugs of proton pump inhibitors May 24, 2005
Prodrugs of proton pump inhibitors of Formulas 1 through 4, ##STR1##where the symbols are as defined in the specification, and the R group includes at least one acidic group or its pharmaceutically acceptable salt, have improved aqueous solubility and bioavailability.
6843998 Methods and compositions for the treatment of pancreatitis January 18, 2005
Methods and compositions for the treatment of acute pancreatitis in a mammal. Particular compositions comprise a binding element, a translocation element, and a therapeutic element able to prevent accumulation of digestive enzymes within the pancreas.
6776990 Methods and compositions for the treatment of pancreatitis August 17, 2004
Methods and compositions for the treatment of acute pancreatitis in a mammal. Particular compositions comprise a binding element, a translocation element, and a therapeutic element able to prevent accumulation of digestive enzymes within the pancreas.
6559167 Prodrugs of proton pump inhibitors May 6, 2003
Prodrugs of the pyridyl methyl sulfinyl benzimidazole type proton pump inhibitor drugs have a hydrolyzable arylsulfonyl or heteroarylsulfonyl group attached to the benzimidazole nitrogen. The prodrugs of the invention hydrolyze under physiological conditions to provide the proton pum
6274173 Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole August 14, 2001
An oral pharmaceutical composition comprises an acid-labile irreversible proton pump inhibitor in pellet or tablet form, wherein the irreversible proton pump inhibitor is at least partly in slow-release form. On combined administration with an anti-microbially-active ingredient, the comp
6271256 Methods for controlling gram negative bacteria in mammals with bicyclo spiroether compounds August 7, 2001
Methods for controlling growth of gram negative bacteria, such as Helicobacter pylori, which are agents associated with disorders of the gastrointestinal tract of a mammal are described. They include administering a therapeutically effective amount of a polyether ionophore antibiotic
6132768 Oral pharmaceutical composition with delayed release of active ingredient for reversible proton October 17, 2000
An oral pharmaceutical composition of a reversible proton pump inhibitor in pellet or tablet form, wherein the reversible proton pump inhibitor is at least partly in slow-release form, is distinguished, on combined administration with an antimicrobially-active ingredient, by an enhanced
6093734 Prodrugs of proton pump inhibitors July 25, 2000
Prodrugs of the pyridyl methyl sulfinyl benzimidazole type proton pump inhibitor drugs have a hydrolyzable sulfinyl or arylsulfonyl group attached to the benzimidazole nitrogen, or include a group that forms a Mannich base with the benzimidazole nitrogen. The prodrugs of the inventio
6068856 Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole May 30, 2000
An oral pharmaceutical composition of pantoprazole in pellet or tablet form, wherein the pantoprazole is at least partly in slow-release form, is distinguished, on combined administration with an antimicrobially-active ingredient, by an enhanced action of rapid onset against disorders ca
6017950 Methods for controlling gram negative bacteria in mammals January 25, 2000
Methods for controlling growth of gram negative bacteria, such as Helicobacter pylori, which are agents associated with disorders of the gastrointestinal tract of a mammal are described. They include administering a therapeutically effective amount of a polyether ionophore antibiotic
5945124 Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole August 31, 1999
An oral pharmaceutical composition of pantoprazole in pellet or tablet form, wherein the pantoprazole is at least partly in slow-release form, is distinguished, on combined administration with an antimicrobially-active ingredient, by an enhanced action of rapid onset against disorders ca
5942409 Process for identification of substances modulating ureI dependent mechanisms of Helicobacter py August 24, 1999
The present invention provides a screening process for the identification of anti-helicobactericidal substances modulating ureI dependent mechanisms of gastric Helicobacter metabolism. Gastric Helicobacter cells are treated with a substance to be tested for modulating ureI dependent mech
5183906 2- and 5-alkyl and phenyl substituted 4-(1-hydroxy, 1-acyloxy or 1-carbamoyloxy)-5-hydroxy-2 (5H February 2, 1993
Novel anti-inflammatory furanone compounds have the following formula ##STR1## where R.sub.1 independently is H, phenyl, C.sub.1 -C.sub.6 alkyl substituted phenyl, halogen substituted phenyl, or alkyl of 1 to 6 carbons and n is an integer having the values of 1 or 2, and where when n
5075323 Compounds including omeprazole in the treatment of glaucoma December 24, 1991
A method for the treatment of diseases related to an increased intraocular pressure in the eye comprising administration to a patient suffering therefrom an amount of a compound of the formula I ##STR1## or a pharmaceutically acceptable salt thereof.
4839385 Use of manoalide and its derivatives for modifying calcium homeostasis June 13, 1989
Compounds derived form the marine sponge Laffariella variabilis and known by the name manoalide, and its derivatives, modify calcium homeostasis.


 
 
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