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Martin Quibell Patents |
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Inventor: Quibell; Martin
Address: Cambridge, GB
No. of patents: 5
Patents:
| Patent Number |
Title Of Patent |
Date Issued |
| 7132449 |
Inhibitors of cruzipain and other cysteine proteases |
November 7, 2006 |
| Compounds of general formula (I): ##STR00001## wherein R.sup.1, R.sup.2, Y, (X).sub.o, (W).sub.n, (V).sub.m, Z and U are as defined in the specification, are inhibitors of cruzipain and other cysteine protease inhibitors and are useful as therapeutic agents, for example in Chagas' d |
| 6958358 |
Inhibitors of cruzipain and other cysteine proteases |
October 25, 2005 |
| Compounds of general formula (I): ##STR1##wherein R.sup.1, Y, (X).sub.o, (W).sub.n, (V).sub.m, Z and U are as defined in the specification, are inhibitors of cruzipain and other cysteine protease inhibitors and are useful as therapeutic agents, for example in Chagas' disease, or for |
| 6528275 |
Substrates and inhibitors of proteolytic enzymes |
March 4, 2003 |
| The present invention relates to the field of compounds which are substrates or inhibitors of proteolytic enzymes and to apparatus and methods for identifying substrates or inhibitors for proteolytic enzymes. We have devised a combinatorial method for the rapid indentification of bin |
| 6372885 |
Solid-phase technology for the preparation of amides |
April 16, 2002 |
| Method for preparing a combinatorial chemistry library of compounds of the formula R1--C(.dbd.O)--NH--R2, wherein R1 and R2 are as defined in the specification, which comprises acylating a combinatorial chemistry intermediate of the formula 1A ##STR1##wherein Y1, Y2, X, n, R1 and R2 |
| 6034066 |
Cysteine protease inhibitors for use in treatment of IGE mediated allergic diseases |
March 7, 2000 |
| The invention provides compounds for use in the treatment of allergic diseases including juvenile asthma and eczema. The compounds can inhibit IgE mediated reaction to major environmental and occupational allergens and can also have a prophylactic effect against allergic disease by p |
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