| Patent Number |
Title Of Patent |
Date Issued |
| 7192583 |
Methods for modulating bone mineralization |
March 20, 2007 |
| Antibodies to a novel family of TGF-.beta. binding proteins are disclosed, for use in methods of altering bone density and bone mineralization, which methods are applicable to the treatment of diseases including osteopenia and osteoporosis. |
| 6803453 |
Antibodies associated with alterations in bone density |
October 12, 2004 |
| Compositions and methods for increasing bone density using antibodies directed to a novel class or family of TGF-.beta. binding proteins are provided. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases associated with a loss |
| 6495736 |
Compositions and methods for increasing bone mineralization |
December 17, 2002 |
| A novel class or family of TGF-.beta. binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules. |
| 6489445 |
Polypeptides associated with alterations in bone density |
December 3, 2002 |
| Compositions and methods for increasing bone density using antibodies directed to a novel class or family human of TGF-.beta. binding proteins are disclosed. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases associated with a lo |
| 6395511 |
Nucleic acids encoding a novel family of TGF-.beta. binding proteins from humans |
May 28, 2002 |
| A novel human protein has been isolated which is encoded by a nucleic acid molecule comprising the polynucleotide sequence provided in SEQ ID NO:1 or a polynucleotide sequence that is completely complementary thereto. This novel protein binds to at least two members of the family of TGF- |
