| Patent Number |
Title Of Patent |
Date Issued |
| 7250299 |
Method and means for producing high titer, safe, recombinant lentivirus vectors |
July 31, 2007 |
| Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR are useful in the production of recombinant lentivirus vectors (See the Figure). Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying |
| 7083981 |
Method and means for producing high titer, safe, recombinant lentivirus vectors |
August 1, 2006 |
| Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene |
| 6924144 |
Method and means for producing high titer, safe, recombinant lentivirus vectors |
August 2, 2005 |
| Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene |
| 6797512 |
Selection system for generating efficient packaging cells for lentiviral vectors |
September 28, 2004 |
| A method for selecting packaging cells that express high levels of gag/pol is provided. |
| 6428953 |
Method and means for producing high titer, safe, recombinant lentivirus vectors |
August 6, 2002 |
| Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene |
| 6165782 |
Method and means for producing high titer, safe, recombinant lentivirus vectors |
December 26, 2000 |
| Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene |
| 6013516 |
Vector and method of use for nucleic acid delivery to non-dividing cells |
January 11, 2000 |
| A recombinant retrovirus capable of infecting a non-dividing cell and a method of producing such a virus is provided. The recombinant retrovirus is preferably of lentivirus origin and is useful for the treatment of a variety of disorders including neurological disorders and disorders of |
| 5994136 |
Method and means for producing high titer, safe, recombinant lentivirus vectors |
November 30, 1999 |
| Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene |