| Patent Number |
Title Of Patent |
Date Issued |
| 4533668 |
Antihyperglycemic moranoline derivatives |
August 6, 1985 |
| N-aralkylmoranoline and N-aralkenylmoranoline, and their pharmaceutical acceptable non-toxic acid addition salts thereof, pharmaceutical compositions containing the same and methods of inhibiting the increase in blood sugar level by administration of the same. |
| 4435397 |
Carbamylpiperazine compounds |
March 6, 1984 |
| 4-(3-Aryloxy-2-hydroxypropyl)piperazines bearing a carbamyl group in the 1-position are .beta.-adrenergic blockers. A typical example is 1-carbamyl-4-{3-[2-allyl-3-(2-carbethoxyaminoethyl)phenoxy]-2-hydroxypropy l}piperazine. |
| 4402948 |
Steroid glycoside compounds and methods of use |
September 6, 1983 |
| Oxygenated sterylglycoside derivatives of the formula (I) wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and each is hydrogen or lower alkanoyl, Y is ##STR1## and R.sub.5 is 4-methylpentyl, 3-ethyl-4-methylpentyl or 3-ethyl-4-methyl-1-pentenyl are useful |
| 4339585 |
Method for the production of 2-hydroxymethyl-3,4,5-trihydroxy piperidine and the corresponding N |
July 13, 1982 |
| Moranoline, or 2-hydroxymethyl-3,4,5-trihydroxy piperidine, is prepared by directly reducing an actinomycetes culture solution containing nojirimycin, followed by isolation, as for example, through the utilization of an ion exchange resin. The corresponding N-methyl derivative can be |
| 4338433 |
Moranoline derivatives and process for preparation thereof |
July 6, 1982 |
| Moranolines are produced which are useful for controlling blood sugar levels. |
| 4336374 |
Quaternary ammonium substituted N-cinnamylpiperidines |
June 22, 1982 |
| 2-Hydroxymethyl-3,4,5-trihydroxypiperidines bearing a quaternary ammonium-substituted cinnamyl group on the piperidine nitrogen atom and their acid addition salts are antihyperglycemic agents. A typical example is 1-(4-trimethylammoniumcinnamyl)-2-hydroxymethyl-3,4,5-trihydroxypiperi |
| 4336373 |
Bis-piperidine compounds |
June 22, 1982 |
| Bis(2-hydroxymethyl-3,4,5-trihydroxypiperidine-1-yl-propenyl) compounds and their acid addition salts are antihyperglycemic agents. Typical examples are 1,4-bis[3-(2-hydroxymethyl-3,4,5-trihydroxypiperidin-1-yl)prop-2-enyl] benzene and 1,3-bis-{4-[3-(2-hydroxymethyl-3,4,5-trihydroxy- |
| 4333933 |
Benzoguanamine derivatives, their production and pharmaceutical compositions containing the same |
June 8, 1982 |
| Novel 2-amino-4-nicotinoylamino-6-halogenophenyl-s-triazines and acid addition salts thereof, possessing strong anti-inflammatory action when the phenyl group is mono- or di-halogen substituted. The compounds are formulated into pharmaceutical compositions in bulk or dosage form, and |
| 4269838 |
Carbamyl piperazine derivatives |
May 26, 1981 |
| 4-(3-Aryloxy-2-hydroxypropyl)piperazines bearing a carbamyl, N-alkyl or N,N-dialkylcarbamyl group in the 1-position are .beta.-adrenergic blockers. A typical example is 1-carbamyl-4-(3-phenoxy-2-hydroxypropyl)piperazine. |
| 4241064 |
9H-Pyrido[3,4-b]indole derivatives |
December 23, 1980 |
| 1-Substituted-9H-pyrido[3,4-b]indole derivatives, which are further optionally substituted in the 3- or 4-position, are inhibitors of xanthine-oxidase. A representative embodiment is 1-formyl-4-hydroxy-9H-pyrido[3,4-b]indole which can be prepared through the processing of Picrasma qu |
| 4211866 |
Acyl derivatives of 2-[3-(2-chloroethyl)-3-nitrosoureido]-2-deoxy-D-glucopyranose |
July 8, 1980 |
| Acylated derivatives of 2-[3-(2-chloroethyl)-3-nitrosoureido]-2-deoxy-D-glucopyranose have antitumor activity. |
| 4198481 |
Process for the preparation of 2-hydroxymethyl-3,4,5-trihydroxy piperidine |
April 15, 1980 |
| 2-Hydroxymethyl-3,4,5-trihydroxy piperidine, or moranoline, is prepared by culturing a moranoline-producing strain of microorganism of the genus Streptomyces in an appropriate culture medium and thereafter isolating moranoline from the culture medium. |
| 4009077 |
Process for the preparation of phenopicolinic acid |
February 22, 1977 |
| Phenopicolinic acid is produced by culturing a strain of Paecilomyces. The compound, which may be alternatively named as 5-(4-hydroxybenzyl)-2-pyridinecarboxylic acid, is a hypotensive agent. |
