| Patent Number |
Title Of Patent |
Date Issued |
| RE39031 |
RNA amplification method requiring only one manipulation step |
March 21, 2006 |
| An RNA amplification method is particularly useful for diagnosing bacterial or viral infections or genetic disorders and for cell typing. The method includes the steps of denaturing a solution containing RNA, synthesizing a first cDNA strand from a suitable primer in the presence of |
| 7335472 |
Method for simultaneously detecting hybridization reactions and immuno-reactions, and its uses i |
February 26, 2008 |
| The present invention relates to a method for simultaneously detecting hybridization reactions and immunoreactions in a sample which may contain target analytes consisting of at least one nucleic acid and of at least one other ligand that is different in nature, characterized in that it |
| 7301041 |
Bi-functional metallocenes, preparation process and use in the labeling or biological molecules |
November 27, 2007 |
| The invention relates to bi-functionalised metallocenes of general formula (I) where Me=a transition metal, preferably chosen from Fe, Ru and Os, Y and Z, when identical are selected from --(CH.sub.2).sub.n--O--, (CH.sub.2)--O--[(CH.sub.2).sub.2--O].sub.P-- and --(CH.sub.2).sub.q--CO |
| 7217457 |
Composite particles, derived conjugates, preparation method and applications |
May 15, 2007 |
| The invention relates to composite particles comprising a hydrophobic polymer core and inorganic nanoparticles. Said hydrophobic polymer forms a polymer matrix inside which the inorganic nanoparticles are stabilized and distributed in a relatively homogenous manner. Said particles are at |
| 7060804 |
Method for isolating proteins or protein and nucleic acid associations, or particle and protein |
June 13, 2006 |
| The invention concerns a method for isolating proteins and/or protein and nucleic acid associations in a sample, comprising steps which consist in: contacting said sample and magnetic colloidal particles comprising a core and a coat wherein: the core is magnetic and is coated with at lea |
| 7001589 |
Composite nanospheres and their conjugates with biomolecules |
February 21, 2006 |
| The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously between 100 and 200 nm plus or minus 5%, and comprising an essentially liquid core consisting |
| 6994314 |
Valves activated by electrically active polymers or by shape-memory materials, device containing |
February 7, 2006 |
| This invention concerns a valve (2), with at least one channel (3) running through it, allowing a fluid (F3) to be directed by transfer means within a device (1), the device (1) featuring at least one face (4), possibly flat, the valve (2) consisting of a film (7 or 16), flexible and/or |
| 6866838 |
Composite nanospheres and their conjugates with biomolecules |
March 15, 2005 |
| The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously between 100 and 200 nm plus or minus 5%, and comprising an essentially liquid core consisting |
| 6828127 |
Method of amplifying an RNA target sequence using an RNA polymerase functioning preferably on RN |
December 7, 2004 |
| Disclosed is a process for transcribing RNA using a nucleotide reagent as the promoter. Such a reagent enables any type of RNA to be transcribed without sequence specification and without protein cofactors, by means of an RNA polymerase that is known to be DNA-dependent such as the RNA |
| 6582703 |
Isolated nucleotide sequences associated with multiple sclerosis or rheumatoid arthritis and a p |
June 24, 2003 |
| The invention provides viral material and nucleotide fragments associated with multiple sclerosis and/or rheumatoid arthritis for use in methods of diagnosis, prophylaxis, and therapy. |
| 6579526 |
Viral material and nucleotide fragments associated with multiple sclerosis, for diagnostic, prop |
June 17, 2003 |
| Viral material, in the isolated or purified state, in which the genome comprises a nucleotide sequence chosen from the group including sequences SEQ ID NO:46, SEQ ID NO:51, SEQ ID NO:52, SEQ ID NO:53 and SEQ ID NO:56, their complementary sequences and their equivalent sequences, in p |
| 6555091 |
Polypeptide capable of reacting with antibodies of patients suffering from multiple sclerosis an |
April 29, 2003 |
| The invention concerns a polypeptide specifically reacting with the antibodies of patients suffering from multiple sclerosis (SEP) and whereof the peptide sequence comprises at least one sequence selected among SEQ ID No. 1 to SEQ ID NO: 19, and their equivalent sequences, and the use of |
| 6521341 |
Magnetic particles, method for obtaining same and uses for separating molecules |
February 18, 2003 |
| The invention concerns magnetic and heat-sensitive particles having a predetermined size between 0.05 and 10 .mu.m, each particle comprising: an inner composite core consisting of a solid organic or inorganic particle, containing within it a magnetic filler; an outer coati based on a pol |
| 6403103 |
Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas |
June 11, 2002 |
| The nucleotide sequence of Tc100, a gene encoding a new antigenic protein from Trypanosoma cruzi called PTc100, is disclosed. The amino acid sequence of the PTc100 protein is also disclosed, along with the amino acid sequence of the dominant antigenic epitope of the PTc100 protein. The |
| 6342396 |
Method for isolating, in particular for detecting or quantifying an analyte in a medium |
January 29, 2002 |
| The present invention relates to a method for at least one of detecting, quantifying or isolating at least one analyte from a liquid medium in which the analyte is distributed and comprises providing a reagent comprised of particles having a receptor for an analyte fixed to the parti |
| 6342383 |
Cell lines and viral isolates associated with multiple sclerosis |
January 29, 2002 |
| Composition comprising two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of said virus, and a se |
| 6270953 |
Method for detecting and/or quantifying a gliotoxic factor |
August 7, 2001 |
| The invention proposes a method for detecting and/or quantifying, in a biological sample, a cytotoxic factor, in particular a gliotoxic factor, with respect to adherent target cells, in particular macroglial cells, the toxicity of which causes the death by apoptosis of said cells. The me |
| 6184025 |
Viral isolates associated with multiple sclerosis |
February 6, 2001 |
| Composition comprising two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of said virus, and a se |
| 6133047 |
Superparamagnetic monodisperse particles |
October 17, 2000 |
| The superparamagnetic monodispersed particles comprise a core of a first polymer, an internal layer of a second polymer coating the core and in which a magnetic material is distributed, and an external layer of a third polymer coating the magnetic layer and capable of interacting with at |
| 6033853 |
Nucleotide sequence detection with signal amplification |
March 7, 2000 |
| Kit for detecting a specific target nucleic acid sequence using a labeled probe with signal amplification, which comprises in containers (i) a probe labeled with a tracer (ii) a suspension of insoluble particles on which are immobilized at least one series of oligonucleotide units all of |
| 6017707 |
Reagent and method for the detection of a nucleotide sequence with signal amplification |
January 25, 2000 |
| Methods for the detection of a nucleotide sequence of interest comprising at least one nucleotide probe marked with a tracer. The methods include a reagent essentially comprising a linear backbone copolymer having lateral substituents, whose chain consists of a first type of repetitive u |
| 6001987 |
Isolated nucleotide sequences associated with Multiple sclerosis |
December 14, 1999 |
| Viral material, in the isolated or purified state, in which the genome comprises a nucleotide sequence chosen from the group including sequences SEQ ID NO:46, SEQ ID NO:51, SEQ ID NO:52, SEQ ID NO:53 and SEQ ID NO:56, their complementary sequences and their equivalent sequences, in p |
| 5988197 |
Freeze valve and treatment enclosure controlled by at least one such valve |
November 23, 1999 |
| A freeze valve for a substantially single-phase fluid contains a pipe designed to receive fluid in a flow area, a cold source and a heat source. The cold source and the heat source are placed in thermal contact with the pipe. The pipe is positioned in relation to the cold source and the |
| 5962217 |
MSRV1 virus and MSRV2 pathogen and/or infective agent associated with multiple sclerosis, and bi |
October 5, 1999 |
| Composition including two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of the virus, and a seco |
| 5902746 |
Assembly for treating a sample in a liquid medium, in particular a biological material |
May 11, 1999 |
| An assembly for treating a sample in a liquid medium, in particular a biological material, includes an essentially static permanently active module, closed off by a chamber from the outside. The assembly includes a disposable outer container holding the sample to be treated, for example |
| 5876954 |
Cytotoxic factor as is associated with multiple sclerosis, its detection and its quantification |
March 2, 1999 |
| Gliotoxic factor in the isolated or purified state, characterized in that it possesses toxic activity with respect to human or animal astrocytic cells, having the effect of a cytomorphological disorganization of their network of intermediate filaments and/or a degradation of the proteins |
| 5871996 |
Retrovirus agents MSRV1 and MSRV2 associated with multiple sclerosis |
February 16, 1999 |
| Composition including two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of the virus, and a seco |
| 5871745 |
Multiple sclerosis related virus |
February 16, 1999 |
| Composition including two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of the virus, and a seco |
| 5824517 |
Method for amplifying nucleic acid sequences by strand displacement using DNA/RNA chimeric prime |
October 20, 1998 |
| A target nucleic acid may be amplified in the presence of an enzymatic system including DNA polymerase, strand translocation and RNAse H activities by using a chimeric primer that includes, in the 5' to 3' direction, an RNA-type segment capable of hybridizing with a 3'-terminal segme |
| 5817465 |
RNA amplification method requiring only one manipulation step |
October 6, 1998 |
| An RNA amplification method is particularly useful for diagnosing bacterial or viral infections or genetic disorders and for cell typing. The method includes the steps of denaturing a solution containing RNA, synthesizing a first cDNA strand from a suitable primer in the presence of reve |
| 5800980 |
Detection of MSRV1 virus and MSRV2 pathogen and/or infective agent associated with multiple scle |
September 1, 1998 |
| Composition including two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of the virus, and a seco |
| 5728540 |
Cytotoxic factor as is associated with multiple sclerosis, its detection and its quantification |
March 17, 1998 |
| Gliotoxic factor in the isolated or purified state, characterized in that it possesses toxic activity with respect to human or animal astrocytic cells, having the effect of a cytomorphological disorganization of their network of intermediate filaments and/or a degradation of the proteins |
| 5723344 |
Device for the capture of target molecules, and capturing process using the device |
March 3, 1998 |
| Device for capturing a target molecule for the purpose of detecting it and/or assaying it, including a solid support on which is immobilized a ligand, the ligand being provided in the form of a conjugate resulting from the covalent coupling of a polymer with a plurality of molecules of |
| 5695936 |
Reagent and method for the detection of a nucleotide sequence with signal amplification |
December 9, 1997 |
| Methods for the detection of a nucleotide sequence of interest comprising at least one nucleotide probe marked with a tracer. The methods comprise use of a reagent essentially comprising a linear backbone copolymer having lateral substituents, whose chain consists of a first type of repe |
| 5695926 |
Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophob |
December 9, 1997 |
| A procedure for detecting single-stranded nucleotide sequences in a sample is disclosed wherein a passively fixed capture probe is used in concert with a non-radioactively labelled detection probe in a sandwich hybridization technique. |
| 5654143 |
RNA amplification method requiring only one manipulation step |
August 5, 1997 |
| An RNA amplification method is particularly useful for diagnosing bacterial or viral infections or genetic disorders and for cell typing. The method includes the steps of denaturing a solution containing RNA, synthesizing a first cDNA strand from a suitable primer in the presence of reve |
