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Donald E. Macfarlane Patents
Inventor:
Macfarlane; Donald E.
Address:
Iowa City, IA
No. of patents:
9
Patents:




Patent Number Title Of Patent Date Issued
7354711 Methods for inhibiting immunostimulatory DNA associated responses April 8, 2008
The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquiniolines. The invention also features methods of screening compounds useful in inhi
6521637 Methods for inhibiting immunostimulatory DNA associated responses February 18, 2003
The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquiniolines. The invention also features methods of screening compounds useful in inhi
6479504 Antagonism of immunostimulatory CpG-oligonucleotides by 4-aminoquinolines and other weak bases November 12, 2002
The present invention relates generally to the field of immunology. More particularly it concerns compositions and methods for inhibiting stimulation of the immune system. The compounds and methods comprise compounds that are analogs and derivatives of chloroquine, such as 4-aminoqui
6399630 Methods for inhibiting immunostimulatory DNA associated responses June 4, 2002
The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquinolines. The invention also features methods of screening compounds useful in inhib
6221882 Methods for inhibiting immunostimulatory DNA associated responses April 24, 2001
The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquiniolines. The invention also features methods of screening compounds useful in inhi
5985572 Quaternary amine surfactant and methods of using same in isolation of RNA November 16, 1999
The present invention discloses a novel method for isolating RNA from biological samples using selected quaternary amine surfactants. The RNA is isolated quickly and in sufficient quantity and quality to permit analysis by methods including reverse transcriptase and polymerase chain reac
5728822 Quaternary amine surfactants and methods of using same in isolation of RNA March 17, 1998
The present invention discloses a novel method for isolating RNA from biological samples, most particularly blood, using selected quaternary amine surfactants. The RNA is isolated quickly and in sufficient quantity and quality to permit analysis by methods including reverse transcriptase
5300635 Quaternary amine surfactants and methods of using same in isolation of nucleic acids April 5, 1994
The present invention discloses a novel method for isolating nucleic acids from biological samples, most particularly blood, using selected quaternary amine surfactants. The nucleic acids are isolated quickly and in sufficient quantity and quality to permit analysis by methods including
5010183 Process for purifying DNA and RNA using cationic detergents April 23, 1991
A novel method is provided for purifying DNA and RNA from a variety of sources, including cells, cell lysates, viruses, tissues, blood and other body fluids employing a cationic detergent to complex with the nucleic acids.


 
 
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