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David M. Lyerly Patents
Inventor:
Lyerly; David M.
Address:
Radford, VA
No. of patents:
6
Patents:




Patent Number Title Of Patent Date Issued
6939548 Methods to produce high levels of C. difficile toxins September 6, 2005
The present invention relates to the field of medical immunology and further to pharmaceutical compositions, methods of making and methods of use of vaccines. More specifically this invention relates to recombinant proteins derived from the genes encoding Clostridium difficile toxin A an
6733760 Recombinant toxin A/toxin B vaccine against Clostridium difficile May 11, 2004
The present invention relates to the field of medical immunology and further to pharmaceutical compositions, methods of making and methods of use of vaccines. More specifically this invention relates to recombinant proteins derived from the genes encoding Clostridium difficile toxin A an
5919463 Clostridium difficle toxins as mucosal adjuvants July 6, 1999
The invention features methods and compositions for inducing protective and/or therapeutic immune responses to an antigen in a mammal. In these methods, an antigen is administered to the mammal with a toxin of a Clostridium (e.g., C. difficile), or a fragment or derivative thereof ha
4879218 Antibody for C.difficile November 7, 1989
Monoclonal antibody to toxin A of C.difficile has been prepared and is used in an assay for toxin A of C.difficile.
4713240 Vaccines based on insoluble supports December 15, 1987
The present invention relates to vaccine compositions which comprise at least one antigen chemically linked to a water-insoluble support combined with a pharmaceutically acceptable carrier. It also relates to a method of stimulating an organism's immune system by administration of these
4533630 Toxins and antibodies of C. difficile August 6, 1985
Mono-specific antibodies for each of toxin A and toxin B of C. difficile are produced and used in an assay for toxin A and toxin B, respectively. Purified toxin A of C. difficile is also produced.


 
 
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