| Patent Number |
Title Of Patent |
Date Issued |
| 6939548 |
Methods to produce high levels of C. difficile toxins |
September 6, 2005 |
| The present invention relates to the field of medical immunology and further to pharmaceutical compositions, methods of making and methods of use of vaccines. More specifically this invention relates to recombinant proteins derived from the genes encoding Clostridium difficile toxin A an |
| 6733760 |
Recombinant toxin A/toxin B vaccine against Clostridium difficile |
May 11, 2004 |
| The present invention relates to the field of medical immunology and further to pharmaceutical compositions, methods of making and methods of use of vaccines. More specifically this invention relates to recombinant proteins derived from the genes encoding Clostridium difficile toxin A an |
| 5919463 |
Clostridium difficle toxins as mucosal adjuvants |
July 6, 1999 |
| The invention features methods and compositions for inducing protective and/or therapeutic immune responses to an antigen in a mammal. In these methods, an antigen is administered to the mammal with a toxin of a Clostridium (e.g., C. difficile), or a fragment or derivative thereof ha |
| 4879218 |
Antibody for C.difficile |
November 7, 1989 |
| Monoclonal antibody to toxin A of C.difficile has been prepared and is used in an assay for toxin A of C.difficile. |
| 4713240 |
Vaccines based on insoluble supports |
December 15, 1987 |
| The present invention relates to vaccine compositions which comprise at least one antigen chemically linked to a water-insoluble support combined with a pharmaceutically acceptable carrier. It also relates to a method of stimulating an organism's immune system by administration of these |
| 4533630 |
Toxins and antibodies of C. difficile |
August 6, 1985 |
| Mono-specific antibodies for each of toxin A and toxin B of C. difficile are produced and used in an assay for toxin A and toxin B, respectively. Purified toxin A of C. difficile is also produced. |