| Patent Number |
Title Of Patent |
Date Issued |
| 7354592 |
Genetically modified tumor-targeted bacteria with reduced virulence |
April 8, 2008 |
| The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic m |
| 6923972 |
Methods for use of genetically modified tumor-targeted bacteria with reduced virulence |
August 2, 2005 |
| The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or r |
| 6863894 |
Genetically modified tumor-targeted bacteria with reduced virulence |
March 8, 2005 |
| The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic m |
| 6685935 |
Vectors for the diagnosis and treatment of solid tumors including melanoma |
February 3, 2004 |
| The present invention is directed to the isolation and use of super-infective, tumor-specific vectors that are strains of parasites including, but not limited to bacteria, fungi and protists. In certain embodiments the parasites include, but are not limited to, the bacterium Salmonel |
| 6475482 |
Genetically modified tumor-targeted bacteria with reduce virulence |
November 5, 2002 |
| The invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume o |
| 6447784 |
Genetically modified tumor-targeted bacteria with reduced virulence |
September 10, 2002 |
| The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic m |
| 6190657 |
Vectors for the diagnosis and treatment of solid tumors including melanoma |
February 20, 2001 |
| The present invention is directed to the isolation and use of super-infective, tumor-specific vectors that are strains of parasites including, but not limited to bacteria, fungi and protists. In certain embodiments the parasites include, but are not limited to, the bacterium Salmonel |
| 6080849 |
Genetically modified tumor-targeted bacteria with reduced virulence |
June 27, 2000 |
| The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or r |