| Patent Number |
Title Of Patent |
Date Issued |
| 6706280 |
Carboxylated phosphatidic acid esters |
March 16, 2004 |
| Novel compounds of formula ##STR1##in which R.sub.1 and R.sub.2 are phospholipid fatty acid residues and A is an aliphatic and/or cycloaliphatic hydrocarbon chain optionally substituted by hydroxy and/or further carboxylic functions. The novel compounds are useful for making liposome |
| 6217849 |
Liposome suspensions as blood pool imaging contrast agents |
April 17, 2001 |
| The present invention concerns injectable blood pool contrast agents for NMR and X-ray imaging purpose. These blood pool agents carry imaging contrast enhancers, e.g. paramagnetic or, respectively, radio-opaque compounds for imaging the circulation and/or circulation targeted organs. |
| 5910300 |
Amphiphilic linkers for coupling administrable diagnostically or physiologically active agents a |
June 8, 1999 |
| Administrable factors or compositions to be directed to specific sites in the body of human and animal patients which comprise a medically and/or diagnostically effective moiety (I) and, coupled thereto by means of a linker (L), a substance (II) having specific affinity for specific site |
| 5833948 |
Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a |
November 10, 1998 |
| The invention concerns NMR imaging contrast compositions comprising magnetically responsive species coupled to physiologically acceptable amphipatic organic substrate materials in the form of mixed micelles suspended or dispersed in a physiologically acceptable aqueous liquid carrier |
| 5626832 |
Injectable opacifying composition containing liposomes of high encapsulation capacity for X-ray |
May 6, 1997 |
| Injectable aqueous composition intended for opacifying certain organs with a view to examination by X-rays. This composition is based on liposomes containing, encapsulated thereein, an aqueous solution of an iodinated opacifying agent. The ratio between the weight of iodine encapsulated |
| 5446918 |
Cable network and modulator-demondulator arrangement for such a network |
August 29, 1995 |
| An interactive cable network for sending information to, and receiving information from a plurality of subscribers. The information is sent from a head-end through a central distributor which includes a plurality of head-end modems each capable of transmitting information at respective |
| 5445810 |
Injectable opacifying composition containing liposomes of high encapsulating capacity for X-ray |
August 29, 1995 |
| Injectable aqueous composition intended for opacifying certain organs with a view to examination by X-rays. This composition is based on liposomes containing, encapsulated thereein, an aqueous solution of an iodinated opacifying agent. The ratio between the weight of iodine encapsulated |
| 5393530 |
Method for making liposomes of enhanced entrapping capacity toward foreign substances to be enca |
February 28, 1995 |
| Liposome vesicles are prepared containing water or very dilute solutions encapsulated therein. These "empty" liposomes are suspended in a carrier liquid containing, dispersed therein, substances of interest to be loaded into the vesicles and incubated for a period of time at temperatures |
| 5312615 |
Injectable opacifying composition containing liposomes of high encapsulation capacity for X-ray |
May 17, 1994 |
| Injectable aqueous composition intended for opacifying certain organs with a view to examination by X-rays. This composition is based on liposomes containing, encapsulated therein, an aqueous solution of an iodinated opacifying agent. The ratio between the weight of iodine encapsulated b |
| 4976962 |
Biodegradable polypeptide and the use thereof for the gradual release of drugs |
December 11, 1990 |
| Biodegradable alkyloxycarbonylmethyl or aryloxycarbonylmethyl polyaspartate and polyglutamate which can be used as a carrier for drugs which are either in the encapsulated state or are incorporated in the polymer matrix. The polypeptide thus loaded degrades enzymatically in the organ |
| 4925818 |
Method of purifying bioactive substances by biospecific adsorption |
May 15, 1990 |
| A ligand specific to a bioactive substance to be purified is fixed, via a connecting silane, to a mineral particulate carrier chosen from among SiO.sub.2, Al.sub.2 O.sub.3, ZrO.sub.2 and TiO.sub.2, the particles of the carrier being submicronic, non-porous and having a large specific sur |
| 4892733 |
Biodegradable synthesis polypeptide and its therapeutic use |
January 9, 1990 |
| Derivatives of polyaspartic and/or polyglutamic acids whose side chains bear COOH groups capable to cyclize into anhydride. These polyacids and anhydrides can be used to manufacture medicines. |
| 4888398 |
Biodegradable polypeptide and the use thereof for the gradual release of drugs |
December 19, 1989 |
| Biodegradable alkyloxycarbonylmethyl or aryloxycarbonylmethyl polyaspartate and polyglutamate which can be used as a carrier for drugs which are either in the encapsulated state or are incorporated in the polymer matrix. The polypeptide thus loaded degrades enzymatically in the organ |
| 4824578 |
Method of purifying bioactive substances by biospecific adsorption |
April 25, 1989 |
| A ligand specific to a bioactive substance to be purified is fixed, through a connecting silane, to a mineral particulate carrier chosen from among SiO.sub.2, Al.sub.2 O.sub.3, ZrO.sub.2 and TiO.sub.2, the particles of the carrier being submicronic, non-porous and having a large specific |
| 4229360 |
Process for the dehydration of a colloidal dispersion of lipsomes |
October 21, 1980 |
| The invention concerns a process for the dehydration of a colloidal dispersion of liposomes in an aqueous liquid medium, this process being aimed at extending the conservation of the liposomes and to enable their efficient use at a later date.According to this process, there is prepared |
