| Patent Number |
Title Of Patent |
Date Issued |
| RE36594 |
Spin trap nitronyl hindered phenols |
February 29, 2000 |
| The invention is the use of nitronyl substituted hindered phenols as antioxidants in therapeutic applications. In the preferred embodiment the compositions have the general formula: ##STR1## Wherein R1 is hydrogen, an alkyl or an aryl and R2 is an alkyl or an aryl; R.sub.3 is an |
| 5900227 |
Multicyclic nitrone spin trapping compositions |
May 4, 1999 |
| Multicyclic nitrone spin trapping compounds capable of forming stable free radical spin adducts are provided as well as methods for their synthesis. The multicyclic nitrone spin trapping compounds can be reacted with a free radical, such as a hydroxy or hydroperoxy radical, in solution t |
| 5681845 |
DMPO spin trapping compositions and methods of use thereof |
October 28, 1997 |
| Spin trapping compositions in general have now been discovered to be effective in treating a variety of disorders, including disorders such as those arising from ischemia, infection, inflammation, exposure to radiation or cytotoxic compounds, not just of the central and peripheral ne |
| 5532277 |
Spin trap nitronyl hindered phenols |
July 2, 1996 |
| The invention is the use of nitronyl substituted hindered phenols as antioxidants in therapeutic applications. In the preferred embodiment the compositions have the general formula: ##STR1## Wherein R1 is hydrogen, an alkyl or an aryl and R2 is an alkyl or an aryl; R.sub.3 is an |
| 5527828 |
Spin trap nitronyl hindered phenols |
June 18, 1996 |
| The invention is the use of nitronyl substituted hindered phenols as antioxidants in therapeutic applications. In the preferred embodiment the compositions have the general formula: ##STR1## Wherein R1 is hydrogen, an alkyl or an aryl and R2 is an alkyl or an aryl; R.sub.3 is an |
| 5455272 |
Spin trap nitronyl hindered phenols |
October 3, 1995 |
| The invention is the use of nitronyl substituted hindered phenols as antioxidants in therapeutic applications. In the preferred embodiment the compositions have the general formula: ##STR1## Wherein R1 is hydrogen, an alkyl or an aryl and R2 is an alkyl or an aryl; R.sub.3 is an |
| 5405967 |
Spin-trap molecules 2-trifluoromethyl- of 5,5-dimethyl-1-dyrroline-N-oxide |
April 11, 1995 |
| Novel spin traps comprising 2-trifluoromethyl-1-DMPO or derivatives thereof have now been found. An effective synthesis method for these spin traps is also disclosed. |