| Patent Number |
Title Of Patent |
Date Issued |
| 7393959 |
Di-aryl substituted pyrrole modulators of metabotropic glutamate receptor-5 |
July 1, 2008 |
| Pyrrole compounds of Formula (I): and pharmaceutically acceptable salts thereof (where A, B, R.sup.11, R.sup.12, R.sup.13, W, X, Y and Z are as defined herein), which are substituted directly, or by a bridge, with i) a heteroaryl moiety containing N adjacent to the point of connection of |
| 7371767 |
Heteroaryl substituted pyrrole modulators of metabotropic glutamate receptor-5 |
May 13, 2008 |
| Pyrrole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depressio |
| 7365074 |
Pyridazine, pyrimidine and pyrazine ethyne compounds |
April 29, 2008 |
| In accordance with the present invention, there is provided a novel class of heterocyclic compounds. Compounds of the invention contain a substituted, unsaturated five, six or seven membered heterocyclic ring that includes at least one nitrogen atom and at least one carbon atom. The |
| 7343485 |
System and method for maintaining protocol status information in a network device |
March 11, 2008 |
| A method may involve: maintaining protocol status information for a network protocol, where the protocol status information includes protocol information generated by a protocol server and network traffic information indicative of how messages are conveyed from the protocol client to |
| 7302744 |
Method of fabricating an acoustic transducer array |
December 4, 2007 |
| A method that involves establishing the performance level of a proposed acoustic transducer array. Deriving a geometric shape for the array based on the established performance level. Selecting piezoceramic materials based on considerations related to the performance level and derived |
| 7274622 |
Nonlinear techniques for pressure vector acoustic sensor array synthesis |
September 25, 2007 |
| The present invention presents a method for use with an acoustic sensor array comprised of a number of pressure-vector sensors capable of sensing the acoustic scalar field and acoustic vector field of an acoustic wave. The method is a signal processing technique that utilizes nonlinear |
| 6855512 |
Methods for identifying inhibitors of cytochrome P450RAI |
February 15, 2005 |
| A method of identifying a compound which is an inhibitor of the enzyme cytochrome P450RAI is performed by selecting a compound that has retinoid activity in an art recognized assay and includes a benzoic acid, benzoic acid ester, naphthoic acid ester or heteroaryl carboxylic acid or este |
| 6720423 |
Dihydrobenzofuran and dihydrobenzothiophene 2,4-pentadienoic acid derivatives having selective a |
April 13, 2004 |
| Compounds of the formula ##STR1## where the variables have the meaning defined in the specification, are specific or selective agonists of RXR retinoid receptors. |
| 6531599 |
Compounds having activity as inhibitors of cytochrome P450RAI |
March 11, 2003 |
| Compounds having Formula 1 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1## |
| 6495552 |
Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI |
December 17, 2002 |
| Novel compounds having the Formulas 1 through 8, wherein the symbols have the meaning defined in the specification, and certain previously known compounds have been discovered to act as inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating d |
| 6399774 |
Compounds having activity as inhibitors of cytochrome P450RAI |
June 4, 2002 |
| Compounds having Formula 1 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1## |
| 6387951 |
Compounds having activity as inhibitors of cytochrome P450RAI |
May 14, 2002 |
| Compounds having Formulas 5 and 6 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1## |
| 6387892 |
Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI |
May 14, 2002 |
| Novel compounds having the Formulas 1 through 8, wherein the symbols have the meaning defined in the specification, and certain previously known compounds have been discovered to act as inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating d |
| 6369225 |
Compounds having activity as inhibitors of cytochrome P450RAI |
April 9, 2002 |
| Compounds having Formula 8 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1## |
| 6359135 |
Compounds having activity as inhibitors of cytochrome P450RAI |
March 19, 2002 |
| Compounds having Formula 1 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1## |
| 6313107 |
Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI |
November 6, 2001 |
| Novel compounds having the Formulas 1 through 8, wherein the symbols have the meaning defined in the specification, and certain previously known compounds have been discovered to act as inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating d |
| 6291677 |
Compounds having activity as inhibitors of cytochrome P450RAI |
September 18, 2001 |
| Compounds having Formula 7 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1## |
| 6252090 |
Compounds having activity as inhibitors of cytochrome P450RAI |
June 26, 2001 |
| Compounds having Formula 1 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1## |
| 6093838 |
Amines substituted with a dihydro-benzofuranyl or with a dihydro-isobenzofuranyl group, an aryl |
July 25, 2000 |
| Compounds of Formula 1 and of Formula 2 ##STR1## where the symbols have the meaning defined in the specification, have retinoid-like biological activity. |
| 5309411 |
Transducer |
May 3, 1994 |
| A transducer apparatus and method for generating sonic sound waves having a far field wavefront amplitude pattern in a Bessel or Gaussian distribution is disclosed. The transducer includes a piezoelectric element having uniformly poled dipoles formed therein. An unpoled backing body havi |
