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Rolf Horlein Patents
Inventor:
Horlein; Rolf
Address:
Frankfurt am Main, DE
No. of patents:
7
Patents:




Patent Number Title Of Patent Date Issued
5637721 Process for the preparation of cephem prodrug esters June 10, 1997
The invention relates to a process which comprises a compound of the formula II ##STR1##
5614623 Diastereomers of 1-(isopropoxycarbonyloxy)ethyl 3-cephem-4-carboxylate and processes for their p March 25, 1997
Enterally absorbable diastereomers of 1-(isopropoxycarbonyloxy)ethyl (6R, 7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(methoxyme thyl)-3-cephem-4-carboxylate of the formula I ##STR1## and their physiologically acceptable salts and also diastereomerically pure s
5589594 Process for the preparation of cephem prodrug esters December 31, 1996
The invention relates to a process for the preparation of cephem prodrug esters of the formula: ##STR1## in which R.sup.1 is C.sub.1 -C.sub.5 -alkanoyloxy-C.sub.1 -C.sub.3 -alkyl or C.sub.1 -C.sub.5 -alkoxycarbonyloxy-C.sub.1 -C.sub.3 -alkyl and X is an inorganic or organic anion
5550232 Diastereomers of 1-(isopropoxycarbonyloxy) ethyl 3-cephem 4-carboxylate August 27, 1996
Enterally absorbable diastereomers of 1-(isopropoxycarbonyloxy)ethyl (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(metho xymethyl)-3-cephem-4-carboxylate of the formula I ##STR1## and their physiologically acceptable salts and also diastereomerically pure sa
5461043 Diastereomers of 1-(isopropoxycarbonyloxy)ethyl 3-cephem-4-carboxylate October 24, 1995
Enterally absorbable diastereomers of 1-(isopropoxycarbonyloxy)ethyl (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(metho xymethyl)-3-cephem-4-carboxylate of the formula I ##STR1## and their physiologically acceptable salts and also diastereomerically pure sa
5405844 Tetracyclic antibiotics and processes for their preparation April 11, 1995
Tetracyclic antibiotics and processes for their preparation .beta.-Lactam antibiotics of the formula I, and their pharmaceutically tolerable salts ##STR1## where X is (CH.sub.2).sub.0-2, CR(a)R(b), O, SO.sub.0-2 or NR(c),R1, R2 and R3 are a multiplicity of substituents, are outstanding
5198544 Process for the preparation of penem compounds March 30, 1993
Compound I ##STR1## is obtained by reaction of compound II with compound III


 
 
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