| Patent Number |
Title Of Patent |
Date Issued |
| 5679583 |
Monoclonal antibodies for the selective immunological determination of intact procollagen peptid |
October 21, 1997 |
| It is possible with the aid of a monoclonal antibody which is specifically directed against an epitope of amino-terminal procollagen peptide (type III) which is not present on the fragment Col 1, and of a second monoclonal or polyclonal antibody against an epitope of amino-terminal p |
| 5620996 |
Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their |
April 15, 1997 |
| The invention relates to sulfonamidocarbonylpyridine-2-carboxesteramides and their pyridine-N-oxides according to the formula I ##STR1## Said compounds are used as pharmaceuticals against fibrotic disorders, as fibrosuppressants and as inhibitors of proline hydroxylase. |
| 5614537 |
2,4-and 2,5-bistetrazolylpyridines, a process for the preparation thereof and the use thereof as |
March 25, 1997 |
| The invention relates 2,4- and 2,5-bistetrazolylpyridines. Said compounds inhibit the enzymes proline hydroxylase and lysine hydroxylase and bring about a selective inhibition of collagen biosynthesis. They are used as fibrosuppressants and immunosuppressants. |
| 5610172 |
Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuti |
March 11, 1997 |
| Sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation, and their use as pharmaceuticalsThe invention relates to sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-N-oxides according to the formula I ##STR1## Said compounds ar |
| 5607954 |
Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process |
March 4, 1997 |
| The invention relates to sulfonamido- and sulfonamido-carbonylpyridine-2-carboxa of the formula I ##STR1## and their use as pharmaceuticals, in particular against fibrotic diseases. |
| 5519038 |
N,N'-bis(alkoxyalkyl)-pyridine-2,4-dicarboxylic acid diamines |
May 21, 1996 |
| The invention relates to N,N'-bis(alkoxyalkyl)-pyridine-2,4-dicarboxylic acid diamides of the formula I ##STR1## wherein R.sup.1, R.sup.2, n, R.sup.1', R.sup.2' and n' have the meanings given. The compounds inhibit proline hydroxylase and lysine hydroxylase and are suitable as f |
| 5482953 |
2,4-and 2,5-bistetrazolylpyridines and the use thereof as pharmaceuticals |
January 9, 1996 |
| The invention relates to 2,4- and 2,5-bistetrazolylpyridines. Said compounds inhibit the enzymes proline hydroxylase and lysine hydroxylase and bring about a selective inhibition of collagen biosynthesis. They are used as fibrosuppressants and immunosuppressants. |
| 5428046 |
Acylsulfonamido- and sulfonamidopyridine-2-carboxylic acid esters and their pyridine N-oxides, p |
June 27, 1995 |
| The invention relates to acylsulfonamido- and sulfonamidopyridine-2-carboxylic acid esters and their pyridine N-oxides of the formula I ##STR1## in whichThe compounds are suitable as medicaments against fibrotic diseases. |
| 5260323 |
2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use |
November 9, 1993 |
| 2,4- and 2,5-substituted pyridine-N-oxides are provided which are effective as fibrosuppressives and immunosuppressives. Said compounds are also suitable for the treatment of disorders of the metabolism of collagen and collagen-like substances or the biosynthesis of Clq. |
| 5240921 |
Cyclic pyridine-2,4- and -2,5-dicarboxylic acid diamides, processes for their preparation and th |
August 31, 1993 |
| The invention relates to cyclic pyridine-2,4- and -2,5-dicarboxylic acid diamides of the formula I ##STR1## in which n and X have the meanings given. The compounds according to the invention inhibit proline hydroxylase and lysine hydroxylase and can accordingly be employed as fib |
| 5204338 |
Oxalylamino acid derivatives and their use as medicaments for inhibiting proline hydroxylase |
April 20, 1993 |
| The invention relates to oxalylamino acid derivatives of the formula I ##STR1## in which R and R' are identical or different and are C.sub.1 -C.sub.6 -alkyl or hydrogen,R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl,R.sup.2 is hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.3 -alkoxy, |
| 5130317 |
Pyrimidine-4,6-dicarboxylic acid diamides, processes for the use thereof, and pharmaceuticals ba |
July 14, 1992 |
| Pyrimidine-4,6-dicarboxylic acid diamides, processes for the use thereof, and pharmaceuticals based on these compoundsThe invention relates to pyrimidine-4,6-dicarboxylic acid diamides of the formula I ##STR1## in which R.sup.1 and R.sup.2 have the meanings given. The compounds a |
