| Patent Number |
Title Of Patent |
Date Issued |
| RE39678 |
Meiosis regulating compounds |
June 5, 2007 |
| Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells. |
| 6884796 |
Meiosis regulating compounds |
April 26, 2005 |
| Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells. |
| 6759400 |
Meiosis regulating compounds |
July 6, 2004 |
| Certain compounds, structurally related to natural compounds which can be extracted i.a. from bull testes and from human follicular fluid, can be used for regulating the meiosis in oocytes and in male germ cells. Some of these compounds are useful in the treatment of infertility, whereas |
| 6653492 |
Preparation of bile acids |
November 25, 2003 |
| Certain bile acids find use in the pharmaceutical industry. In view of the wide distribution of serious diseases such as HIV, AIDS and Bovine Spongiform Encephalopathy (BSE) it is desirable to avoid--as far as practicable--to have any components of animal origin in medicaments in ord |
| 6645953 |
Meiosis regulating compounds |
November 11, 2003 |
| Sterol derivative compounds, structurally related to natural compounds which can be extracted from bull testes and from human follicular fluid, useful for regulating meiosis in oocytes and in male germ cells. Some of these compounds are useful in the treatment of infertility, whereas oth |
| 6486145 |
Meiosis regulating compounds |
November 26, 2002 |
| Certain compounds, structurally related to natural compounds which can be extracted i.a. from bull testes and from human follicular fluid, can be used for regulating the meiosis in oocytes and in male germ cells. Some of these compounds are useful in the treatment of infertility, whereas |
| 6407086 |
Meiosis regulating compounds |
June 18, 2002 |
| Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells. |
| 5783575 |
Antagonists, their preparation and use |
July 21, 1998 |
| The present invention relates to therapeutically active non competitive antagonists, acting selectively at the metabotropic glutamate receptor. The novel compounds are useful in treating diseases in the central nervous system by modulating synaptic transmission via the metabotropic gluta |
| 5646146 |
Heterocyclic compounds and their preparation and use |
July 8, 1997 |
| The present invention relates to 9H-indeno[1,2-b]pyrazin-3(4H)-ones and 9H-indeno[1,2-b]pyrazine-2,3(1H,4H)-diones or tautomeric forms thereof which are useful in treating neurological and psychiatric diseases based on the antagonism of the glycine binding site on the NMDA receptor c |
| 5536721 |
Thieno[2,3-b-indole derivatives and their use for treating central nervous system diseases relat |
July 16, 1996 |
| The present invention relates to therapeutically active heterocyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system related to the metabotropic gl |
| 5468748 |
9H-indeno[1,2-b]pyrazine derivatives |
November 21, 1995 |
| The present invention relates to 9H-indeno[1,2-b]pyrazin-3(4H)-ones and 9H-indeno[1,2-b]pyrazine-2,3(1H,4H)-diones or tautomeric forms thereof which are useful in treating neurological and psychiatric diseases based on the antagonism of the glycine binding site on the NMDA receptor c |
| 5284847 |
Thieno pyrazine diones, their preparation and use |
February 8, 1994 |
| Novel thieno[2,3-b]pyrazine-2,3(1H,3H)-diones or tautomeric forms thereof of the formula (I) ##STR1## The compounds are useful in the treatment of neurological and psychiatric diseases. |
| 5227488 |
Aza spiro decane and use thereof in treating CNS disorders |
July 13, 1993 |
| Indole derivatives of formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 may be hydrogen or lower alkyl optionally substituted by halogen; X represents oxygen or sulfur; A.sup.1 represents a straight or branched alkylene chain containing from 2 to 4 carbon atoms; |
| 5182279 |
Benzothienopyrazinedione compounds and their preparation and use |
January 26, 1993 |
| Novel [1]benzothieno[2,3-b]pyrazine-2,3(1H,4H)-diones or tautomeric forms thereof of the general formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently represent hydrogen, halogen, alkyl, alkoxy or trifluoromethyl.The compounds are useful for treating a cent |
| 5166155 |
Quinoxaline-2,3-dione compounds and their preparation and use |
November 24, 1992 |
| 1-carboxyalkylquinoxaline-2,3(1H,4H)-dione compounds or tautomeric forms thereof of the formula ##STR1## wherein R represents hydrogen, C.sub.1-6 -alkyl, including branched chains, or aralkyl and n represents the number from 0 to 5;R.sup.4 represents hydrogen or hydroxy;R.sup.5, R.su |
| 5126363 |
Indole derivatives and their use |
June 30, 1992 |
| Indole derivatives of formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 may be hydrogen or lower alkyl optionally substituted by halogen; A.sup.1 represents a straight or branched alkylene chain containing from 2 to 4 carbon atoms; R.sup.5 is hydrogen or a straig |
| 5025009 |
Novel benzazepine derivatives |
June 18, 1991 |
| Novel 2,3,4,5-tetrahydro-1H-3-benzazepines having the formula ##STR1## wherein R.sup.3 represents H, C.sub.1-3 -alkyl or C.sub.3-7 -cycloalkyl;R.sup.4 represents hydrogen or R.sup.4 together with R.sup.10 represents a bridge which connects the positions to which R.sup.4 and R.sup.10 are |
| 5017571 |
Carbamic acid ester of substituted 7-hydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines |
May 21, 1991 |
| Compounds having the formula ##STR1## wherein R.sup.1, R.sup.4, R.sup.6, R.sup.7, and R.sup.8 are hydrogen or a substituent, R.sup.2 is a substituent, R.sup.5 is an optionally-substituted bicyclic ring system, especially a 7-benzofuranyl or 2,3-dihydrobenzofuran-7-yl substituent, |
| 5010074 |
Novel benzazepine derivatives |
April 23, 1991 |
| Novel 2,3,4,5-tetrahydro-1H-3-benzazepines having the formula ##STR1## wherein R.sup.3 represents H, C.sub.1-3 -alkyl or C.sub.3-7 -cycloalkyl; R.sup.4 represents hydrogen or R.sup.4 together with R.sup.10 represents a bridge which connects the positions to which R.sup.4 and R.sup.10 |
| 4082745 |
Process for the preparation of phosphorus derivatives of secondary ammonium salts of penam and c |
April 4, 1978 |
| An improvement in the conversion of penam and cephem compounds to secondary ammonium salts of phosphite amides thereof by reacting as follows: ##STR1## wherein --R, is the non-reacting balance of the penam or cephem compound and ##STR2## ARE NON-REACTING SUBSTITUENTS. Catalyt |
| 4003896 |
Method of preparing a sparingly soluble complex of cephalexin |
January 18, 1977 |
| Method of recovering high purity cephalexin in high yields from a solution containing cephalexin comprising the steps of reacting said solution with a non-substituted or substituted naphthalene to form a complex with cephalexin, isolating said complex, and decomposing said complex to |
| 3994883 |
Penicillin and cephalosporin intermediates |
November 30, 1976 |
| Novel penicillin and cephalosporin intermediates for the synthesis of 6-APA or 7-aminocephem compounds involving formation of a 6 or 7 phosphite amido compound and the conversion of such compound to a desired 6-APA or 7-aminocephem compound. |
