| Patent Number |
Title Of Patent |
Date Issued |
| 6077236 |
Apparatus for monitoring cardiac contractility |
June 20, 2000 |
| Apparatus for monitoring cardiac contractility comprises a catheter having a tip for insertion into the ventricle of the heart muscle. At or proximate the tip is an acceleration transducer responsive to the natural, multi-directional heart acceleration to provide an acceleration signal t |
| 5624817 |
Mutations in the gene encoding the alpha chain of platelet glycoprotein Ib |
April 29, 1997 |
| The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide more reactive with yon Willebrand factor. Preferably, the mutation is in the hinge region of GP Ib.alpha., such |
| 5593959 |
Mutations in the gene encoding the alpha chain of platelet glycoprotein Ib |
January 14, 1997 |
| The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide more reactive with von Willebrand factor. Preferably, the mutation is in the hinge region of GP Ib.alpha., such |
| 5492809 |
Mutations rendering platelet glycoprotein Ib-.alpha. less reactive |
February 20, 1996 |
| The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide less reactive with von Willebrand factor. Preferably, the mutation is in the leucine rich region of GPIb.alpha. |
| 5317097 |
Mutations in the gene encoding the .alpha. chain on platelet glycoprotein IB |
May 31, 1994 |
| The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide more reactive with von Willebrand factor. Preferably, the mutation is in the hinge region of GP Ib.alpha., such |
| 5298239 |
Mutations rendering platelet glycoprotein IB .alpha. less reactive |
March 29, 1994 |
| The subject invention provides purified polypeptide encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide less reactive with von Willebrand factor. Preferably, the mutation is in the leucine rich region of GPIb.alpha., |