| Patent Number |
Title Of Patent |
Date Issued |
| 5600015 |
Assymetric hydrogenation of isoprene derivatives |
February 4, 1997 |
| There is described a process for the manufacture of isoprene derivatives of the general formula ##STR1## wherein the asymmetric centres can each individually have the (R)- or (S)-configuration, R represents a residue of the formulae ##STR2## R.sup.1 signifies lower alkyl or b |
| 5543559 |
Process for the enantioselective hydrogenation of ketosiophorone derivatives |
August 6, 1996 |
| The present invention is concerned with a process for the manufacture of optically active compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy, phenyl, benzyl or --NR.sub.2.sup.1, R.sup.1 signifies lower alkyl, phenyl, benzyl or hydrogen and * signifies |
| 5516944 |
Optically active phosphorous compounds |
May 14, 1996 |
| The present invention is concerned with novel optically active phosphorus compounds of the general formula ##STR1## wherein R and R.sup.1 each independently signify hydroxy, a protected hydroxy group, lower alkyl or lower alkoxy andR.sup.2 to R.sup.5 each independently signify alkyl |
| 5514805 |
Assymetric synthesis process |
May 7, 1996 |
| A novel process for the asymmetric hydrogenation of compounds of the formula: ##STR1## wherein R represent aryl or heteroaryl, to compounds of the formula: ##STR2## wherein R has the above significance, is carried out using rhodium-diphosphine complexes. |
| 5508438 |
Phosphorus compounds |
April 16, 1996 |
| Novel, racemic and optically active phosphorus compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy, hydroxy or a protected hydroxy group, R.sup.1 and R.sup.2 are different from each other and represent lower alkyl, cycloalkyl, aryl, a five-membered heteroa |
| 5481008 |
Process for the preparation of optically active compounds |
January 2, 1996 |
| A catalytic process for the manufacture of optically active compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are alkyl, which is optionally interrupted by an O atom in a position other than the .alpha.-or .beta.-position, or optionally substituted benzyl,R.sup.3 is h |
| 5374727 |
Asymmetric hydrogenation of dihydro-pyrido [1,2-a]indoles |
December 20, 1994 |
| A process for the asymmetric hydrogenation of 6,7-dihydropyrido[1,2-a]indole-8-methanol or its aromatically-substituted derivatives of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 each, independently, is hydrogen, halogen, C.sub.1-7 -alkyl, C.sub.1-7 -haloalkyl, hydr |
| 5360908 |
Isoquinoline derivatives |
November 1, 1994 |
| A process for the preparation of isoquinoline derivatives of the formulas ##STR1## wherein R.sup.1 and R.sup.2 have the significances herein after set forth in the description, is described.The compounds of formula IV are obtained by asymmetrically hydrogenating the compounds of form |
| 5288928 |
Asymmetrical hydrogenation |
February 22, 1994 |
| There is disclosed a process for the asymmetrical hydrogenation of (E)-2-methyl-3-phenyl-2-propen-1-ol of formula ##STR1## wherein R.sub.1 is as defined herein, to give compounds of formula ##STR2## The catalyst is a neutral or cationic rhodium complex of a chiral atropisomer |
| 5274125 |
Chirale phosphines |
December 28, 1993 |
| Novel, racemic and optically active phosphorus compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy or a protected hydroxy group, R.sup.1 signifies a five membered heteroaromatic ring, R.sup.2 stands for lower alkyl or lower alkoxy and n represents the numb |
| 5142063 |
Chiral rhodium-diphosphine complexes |
August 25, 1992 |
| The present invention describes novel chiral rhodium-diphosphine complexes having the formulawherein X represents a residue of the formula X--COO.sup.- in which Z signifies a group ##STR1## aryl or substituted aryl, wherein R.sup.1, R.sup.2, R.sup.3 =hydrogen, halogen, lower alky |
| 4857648 |
Isoquinoline derivatives |
August 15, 1989 |
| The invention is concerned with novel isoquinoline derivatives of the formula ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, lower alkoxy, aryl, aryloxy, aryl-lower alkyl or aryl-lower alkoxy andR.sup.2 is phenyl or substituted phenyl.These novel isoquinoline derivatives are valu |
| 4652657 |
Chiral rhodium-diphosphine complexes |
March 24, 1987 |
| There are described novel chiral rhodium-diphosphine complexes of the formulawherein X, which may be fixed to a carrier, is Z--COO.sup.-, wherein Z is ##STR1## perfluorophenyl, perfluorobiphenyl or a residue of the formula ##STR2## and R.sup.1, R.sup.2 and R.sup.3 is halogen, low |
| 4620013 |
Chiral phosphines |
October 28, 1986 |
| Novel chiral phosphines are disclosed which when complexed with rhodium provide catalyst compositions for asymmetric hydrogenations. |
| 4544770 |
Catalytic hydrogenation |
October 1, 1985 |
| Compounds of the formula: ##STR1## wherein R.sup.1 is a 2,6,6-trimethyl-1-cyclohexen-1-yl or 2,3,6-trimethylphenyl group, either of which may be unsubstituted or substituted by a hydroxy group or a protected hydroxy group, R.sup.2 is aryl, and X.sup.- is an anionare manufactured |
| 4539411 |
Rhodium complexes of chiral phosphines |
September 3, 1985 |
| Novel chiral phosphines are disclosed which when complexed with rhodium provide catalyst compositions for asymmetric hydrogenations. |
| 4283559 |
Process for the manufacture of cyclohexene derivatives |
August 11, 1981 |
| The compound 6-hydroxy-3-(5-hydroxy-3-methyl-1,3-pentadienyl)-2,4,4-trimethyl-2-cyclohe xen-1-one useful as intermediate for producing the natural coloring agent astaxanthin as well as a method for synthesizing astaxanthin from this compound and synthesizing the compound from 2-hydrox |
| 4249023 |
Process for manufacturing triphenylphosphine |
February 3, 1981 |
| A process is disclosed for producing triphenylphosphine in which a triphenylphosphine dichloride-chloroform adduct, obtained by reacting triphenylphosphine oxide with phosgene in chloroform, is reduced with hydrogen. The reduction proceeds in a chloroform solvent or in the absence of |
| 4246204 |
Process for manufacturing triphenylphosphine |
January 20, 1981 |
| A process is disclosed for producing triphenylphosphine by hydrogenating triphenylphosphine dichloride in an inert solvent in the presence of a platinum, palladium, rhodium, ruthenium and/or iridium catalyst. |
