| Patent Number |
Title Of Patent |
Date Issued |
| 7399834 |
Anti-PRO1558 antibodies |
July 15, 2008 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7368558 |
PRO357 nucleic acids |
May 6, 2008 |
| The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides |
| 7332280 |
Classification of patients having diffuse large B-cell lymphoma based upon gene expression |
February 19, 2008 |
| Methods and kits for classifying patients having diffuse large B-cell lymphoma (DLBCL) based upon expression of a plurality of genes are disclosed. Real-time quantitative RT-PCR can be used to measure expression values. Correlating expression values of the plurality of genes in a tum |
| 7258983 |
Cardiotrophin-1 compositions and methods for the treatment of tumor |
August 21, 2007 |
| The invention concerns composititions and methods for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals, including humans. The invention is based on the identification of cardiotrophin-1 gene amplified in the genome of tumor cells. Such gene amplifica |
| 7244816 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
July 17, 2007 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7208308 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
April 24, 2007 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7196165 |
PRO363 polypeptides |
March 27, 2007 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7189566 |
PRO347 nucleic acids |
March 13, 2007 |
| The present invention is directed to novel polypeptides having homology to cysteine-rich secretory protein-3 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cell comprising those nucleic acid sequences, chimeric polypeptide molecules |
| 7189530 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
March 13, 2007 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7189529 |
PRO792 nucleic acids |
March 13, 2007 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7166282 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
January 23, 2007 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7157247 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
January 2, 2007 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7118853 |
Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors |
October 10, 2006 |
| The invention provides a variety of reagents for use in the diagnosis and management of breast cancer. The invention utilizes cDNA microarray technology to identify genes whose expression profile across a large group of tumor samples correlates with that of cytokeratin 5 and cytokera |
| 7109318 |
Nucleic acids encoding PRO830 |
September 19, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7101984 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
September 5, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7098312 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
August 29, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7094567 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
August 22, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7087738 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
August 8, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7074592 |
Secreted and transmembrane polypeptides nucleic acid encoding |
July 11, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7070979 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
July 4, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7070955 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
July 4, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7056736 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
June 6, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7041805 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
May 9, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7034123 |
Anti-PRO1347 antibodies |
April 25, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7033786 |
Pro1340 nucleic acids |
April 25, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7026449 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
April 11, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7026448 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
April 11, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 7018837 |
Nucleic acids encoding secreted polypeptides that stimulate release of proteoglycans from cartil |
March 28, 2006 |
| The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides |
| 7018811 |
Nucleic acids encoding PRO189 polypeptides |
March 28, 2006 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invent |
| 6974696 |
PRO853 nucleic acids |
December 13, 2005 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6974689 |
Nucleic acid encoding PRO211 polypeptides |
December 13, 2005 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6965011 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
November 15, 2005 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6936436 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
August 30, 2005 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6936254 |
Method of inducing fetal hemoglobin synthesis |
August 30, 2005 |
| The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides |
| 6929947 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
August 16, 2005 |
| The present invention is directed to nucleic acids encoding a secreted polypeptide that inhibits neoplastic growth in tumor cells. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the pr |
| 6913919 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
July 5, 2005 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6908993 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
June 21, 2005 |
| The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides |
| 6764679 |
Antibodies to DcR3 Polypeptide, a TNFR Homolog |
July 20, 2004 |
| A TNFR homolog, identified as DcR3, is provided. Nucleic acid molecules encoding DcR3, chimeric molecules and antibodies to DcR3 are also provided. |
| 6723535 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
April 20, 2004 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6664376 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
December 16, 2003 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6635468 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same |
October 21, 2003 |
| The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention |
| 6551822 |
NL4 tie ligand homologue |
April 22, 2003 |
| The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligands NL1, NL5, NL8, and NL4, the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules. |
| 6472585 |
Cardiotrophin-1 defective mouse |
October 29, 2002 |
| The invention concerns composititions and methods for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals, including humans. The invention is based on the identification of cardiotrophin-1 gene amplified in the genome of tumor cells. Such gene amplifica |
| 6413770 |
NL4 tie ligand homologue nucleic acid |
July 2, 2002 |
| The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligands NL1, NL5, NL8, and NL4, the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules. |
| 5770426 |
Tissue plasminogen activator having zymogenic or fibrin specific properties |
June 23, 1998 |
| Tissue plasminogen activator (t-PA) zymogens and variants are prepared, including a fibrinolytically active variant of t-PA that has an amino acid alteration at a site within the protease domain of t-PA as compared with the corresponding wild-type t-PA, which alteration renders the varia |
| 5728567 |
Tissue plasminogen activator having zymogenic or fibrin specific properties |
March 17, 1998 |
| Tissue plasminogen activator (t-PA) zymogens and variants are prepared, including a fibrinolytically active variant of t-PA that has an amino acid alteration at a site within the protease domain of t-PA as compared with the corresponding wild-type t-PA, which alteration renders the varia |
| 5714145 |
Tissue plasminogen activator having zymogenic or fibrin specific properties |
February 3, 1998 |
| Tissue plasminogen activator (t-PA) zymogens and variants are prepared, including a fibrinolytically active variant of t-PA that has an amino acid alteration at a site within the protease domain of t-PA as compared with the corresponding wild-type t-PA, which alteration renders the varia |
| 5677153 |
Methods for modifying DNA and for detecting effects of such modification on interaction of encod |
October 14, 1997 |
| The invention relates to methods and mutation linkers to modify DNA, to methods for producing libraries containing a multiplicity of modified DNA, and to methods for using such libraries for screening modified proteins encoded by such DNA. The DNA targeted for modification typically enco |
| 5616486 |
Tissue plasminogen activator having zymogenic or fibrin specific properties |
April 1, 1997 |
| Tissue plasminogen activator (t-PA) zymogens and variants are prepared, including a fibrinolytically active variant of t-PA that has an amino acid alteration at a site within the protease domain of t-PA as compared with the corresponding wild-type t-PA, which alteration renders the varia |
| 5614190 |
Tissue plasminogen activator having zymogenic or fibrin specific properties |
March 25, 1997 |
| Tissue plasminogen activator (t-PA) zymogens and variants are prepared, including a fibrinolytically active variant of t-PA that has an amino acid alteration at a site within the protease domain of t-PA as compared with the corresponding wild-type t-PA, which alteration renders the varia |
