| Patent Number |
Title Of Patent |
Date Issued |
| H1893 |
Enzymatic reduction method for the preparation of halohydrins |
October 3, 2000 |
| An enzymatic reduction method, particularly a stereoselective enzymatic reduction method, for the preparation of halohydrins from haloketones. The halohydrin products are particularly useful in the preparation of epoxides, which may be employed as intermediates in the preparation of |
| H1679 |
Process for preparing an optically pure intermediate for a phosphonosulfonate soualene synthetas |
September 2, 1997 |
| A process is provided for preparing a substantially optically pure phosphonate ester or phosphonate thioester intermediate via an enzymatically catalyzed enantioselective reaction, which intermediate is employed in preparing phosphonosulfonate squalene synthetase inhibitors. |
| 7034152 |
Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta )]-2-amino-1,9-dihydro-9-[4- |
April 25, 2006 |
| Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed. |
| 6649387 |
Enzymatic oxidative deamination process |
November 18, 2003 |
| The present invention concerns an enzymatic oxidative deamination process of a dipeptide monomer to prepare an intermediate useful to prepare compounds having endopeptidase and angiotensin converting enzyme inhibition activity. |
| 6515170 |
Enzymatic oxidative deamination process |
February 4, 2003 |
| The present invention concerns an enzymatic oxidative deamination process of a dipeptide monomer to prepare an intermediate useful to prepare compounds having endopeptidase and angiotensin converting enzyme inhibition activity. |
| 6261810 |
Enzymatic oxidative deamination process |
July 17, 2001 |
| The present invention concerns an enzymatic oxidative deamination process of a dipeptide monomer to prepare an intermediate useful to prepare compounds having endopeptidase and angiotensin converting enzyme inhibition activity. |
| 5686298 |
Enzymatic reduction method for the preparation of compounds useful for preparing taxanes |
November 11, 1997 |
| An enzymatic reduction method, particularly a stereoselective enzymatic reduction method, for the preparation of compounds useful as intermediates in the preparation of taxanes. |
| 5478734 |
Method of chiral epoxidation of benzopyran or pyranopyridine derivatives using microorganisms |
December 26, 1995 |
| An enzymatic process for the preparation of chiral epoxides, monohydroxy or dihydroxy compounds of formula ##STR1## by the stereoselective epoxidation or hydroxylation of benzopyrans of formula ##STR2## or resolution of compounds of formula ##STR3## The compounds of f |
| 5420337 |
Enzymatic reduction method for the preparation of compounds useful for preparing taxanes |
May 30, 1995 |
| An enzymatic reduction method, particularly a stereoselective enzymatic reduction method, for the preparation of compounds useful as intermediates in the preparation of taxanes. |
| 5393663 |
Stereoselective preparation of halophenyl alcohols from ketones |
February 28, 1995 |
| A process is described for selectively preparing a compound of the formula ##STR1## wherein: R.sup.1 is halogen;R.sup.2 is halogen, alkyl, cycloalkyl, aryl or ##STR2## and R.sup.3 hydrogen, alkyl, cycloalkyl, aryl, ##STR3## wherein the process comprises treating the associate |
| 5391495 |
Stereoselective reduction of ketones |
February 21, 1995 |
| The present invention concerns a process for the stereoselective enzymatic reduction of keto group-containing compounds such as N-(4-(2-chloroacetyl)phenyl)methanesulfonamido to form the corresponding hydroxyl-group containing compound. The process is selective for the D(+) enantiome |
| 5324662 |
Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5 |
June 28, 1994 |
| Microorganisms or reductases derived therefrom reduce a diketo ester ##STR1## to form the associated 3-hydroxy, 5-hydroxy, or 3,5-dihydroxy esters. Selected microorganisms produce the preferred stereoisomers ##STR2## which can be used to prepare antihypercholesterolemic agents su |
