| Patent Number |
Title Of Patent |
Date Issued |
| 6902584 |
Bone grafting matrix |
June 7, 2005 |
| A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix and having a particle size of 5 microns or less. |
| 6776761 |
Hollow microspheres with controlled fragility for medical use |
August 17, 2004 |
| A composition for ultrasonic imaging is described having a microbubble population of controlled fragility. The microbubbles comprise an outer shell and a hollow core. The ratio of shell thickness to microbubble diameter is substantially similar across the population of microbubbles. A |
| 6764517 |
Tissue repair matrix |
July 20, 2004 |
| A porous three-dimensional tissue repair matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix. |
| 6524608 |
Intravesical drug delivery system |
February 25, 2003 |
| Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provided sustained release of drugs. Configurations are provided which are insertable through a catheter, such as a coiled filament, patch or a flowable gel. The device is bi |
| 6458140 |
Devices and methods for interconnecting vessels |
October 1, 2002 |
| The present invention provides implantable devices and associated methods forinterconnecting human vessels in a side-to-side or an end-to-side arrangement rapidly, safely and in a minimally invasive manner. The devices comprises at least a first segment, a second component, and a flow |
| 6207180 |
Intravesical drug delivery |
March 27, 2001 |
| Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provide sustained release of drugs. Configurations are provided which are insertable through a catheter, such as a coiled filament, patch or a flowable gel. The device is bio |
| 6193951 |
Microparticles useful as ultrasonic contrast agents |
February 27, 2001 |
| Microparticles are provided comprising a shell of an outer layer of a biologically compatible material and an inner layer of biodegradable polymer. The core of the microparticles contain a gas, liquid or solid for use in drug delivery or as a contrast agent for ultrasonic contrast im |
| 6187047 |
Bone grafting matrix |
February 13, 2001 |
| A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix and having a particle size of 5 microns or less. |
| 6039967 |
Intravesical drug delivery system |
March 21, 2000 |
| Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provide sustained release of drugs. Configurations are provided which are insertable through a catheter, such as a coiled filament, patch or a flowable gel. The device is bio |
| 5948427 |
Microparticulate surgical adhesive |
September 7, 1999 |
| Flowable polymeric microparticulate surgical adhesive formulations are provided which can be activated at the site of the repair to produce a cohesive material with tissue bonding properties to adjacent tissues. The formulation may be activated at the site of repair by mechanical shear |
| 5776193 |
Bone grafting matrix |
July 7, 1998 |
| A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix and having a particle size of 5 microns or less. |
| 5749895 |
Method for bonding or fusion of biological tissue and material |
May 12, 1998 |
| Biological materials are joined, repaired or fused by heating the material in proximity to a mechanical support. Preferably, the mechanical support comprises a patch or bridge structure. In the most preferred embodiment, the patch is formed from collagen having a thickness from between 2 |
| 5731005 |
Hydrogel-based microsphere drug delivery systems |
March 24, 1998 |
| The present invention provides a sustained-release delivery composition for ophthalmic drugs comprising cross-linked hydrogel microspheres having a binding affinity for the drug. |
| 5487895 |
Method for forming controlled release polymeric substrate |
January 30, 1996 |
| A method for forming a controlled release polymeric substrate is provided by contacting a polymeric substrate with a liquid mixture containing a cross-linking agent at least partially soluble therein comprising water and an organic liquid, for a period of time and at a temperature and |
| 5358706 |
Muco-adhesive polymers |
October 25, 1994 |
| Cationic polysaccharide polymers and anionic therapeutic agents delivery systems are disclosed which have been found to be substantive to mucosal surfaces. The present delivery system is well suited for the delivery of anionic ophthalmic pharmaceuticals. |
