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Inventor:
Wurziger; Hanns
Address:
Darmstadt, DE
No. of patents:
35
Patents:












Patent Number Title Of Patent Date Issued
8133887 Oxaphenanthrene derivatives March 13, 2012
The invention relates to compounds of the formula (I), in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, Y and A have the meanings indicated, and to processes for the preparation thereof and to the use thereof for the preparation of medicaments. ##STR00001##
7687624 Process for the production of N-arylmorpholinones March 30, 2010
The invention relates to a method for production of compounds of formula (I), where X has the meaning given in claim 1 and precursors for the same.
7579346 Carboxamides August 25, 2009
Novel compounds of the formula (I), in which D, W, X, Y, T, m and R.sup.1 have the meaning indicated in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.
7431891 Device for controlling the temperature of chemical microreactors October 7, 2008
In a device for the temperature control of microcomponents, in particular micro-reactors, which preferably have a plate-shaped design and preferably consist of silicon, at least one microcomponent is pressed against a temperature-control element in a holder. A flat heat-conducting co
7271302 Method for brominating organic compounds September 18, 2007
The present invention relates to processes for the bromination of organic compounds, and to bromination microreactors for carrying out these processes.
7179925 Method for reducing organic compounds in microreactor by means of hydrides and/or the derivative February 20, 2007
The present invention relates to a process for the reduction of aliphatic, aromatic or heterocyclic organic compounds by means of hydrides and/or derivatives thereof.
7132081 Device used in parallel microsynthesis November 7, 2006
Microwells, which are open on both sides and are arranged two-dimensionally in a microwell matrix (4), are hermetically closed by pressure on both sides using plugs (6) covered with a sealing sheet (11). A layer of elastic material (9), which is arranged between the plug (6) and the
7098357 Method for dehydrating organic compounds in a microreactor August 29, 2006
The present invention relates to a process for the dehydration of organic compounds to give unsaturated compounds.
7060894 Device for connecting microcomponents June 13, 2006
In a device for connecting microcomponents, in particular microreactors, which preferably have a plate-shaped design and preferably consist of silicon, a sealing plate having apertures which correspond to apertures in the microcomponents is arranged between the microcomponents.
7009059 Method for the 1,3 dipolar cycloaddition of organic compounds in a microreactor March 7, 2006
The invention relates to a method for the 1,3 dipolar cycloaddition of organic compounds, characterized in that the reaction is carried out in a microreactor.
7001576 Emulsifying and separating device for liquid phases February 21, 2006
A device for the emulsification and separation of small amounts of immiscible liquid phases has essentially a cover plate (2), which can be tightly connected to a base plate (1), where microchannels (4,4a,5,6,6a) in the form of grooves are cut out on the inner surface (3,3a) of the b
6977304 Method for producing indoles December 20, 2005
The present invention relates to a process for the preparation of indoles.
6929781 Interconnection support for plate-like microcomponents August 16, 2005
An interconnection support for plate-like microcomponents (1) has a support rail (2) which is attached to a support plate (3). An insertion slot (4) for the support rail (2) accommodates an insertion edge (5) of a plate-like microcomponent (1). Like connections (10, 10a), which can be
6921829 Method for formulating organic compounds July 26, 2005
The invention generally relates to a method of formylating organic compounds in a microreactor.
6861527 Nitration in a static micromixer March 1, 2005
The present invention relates to a novel process for the nitration of organic compounds, preferably of aromatic and heteroaromatic compounds, using nitrating reagents which are known from the literature and new types of nitrating reagents.
6852900 Method for carrying out a metathesis reaction of unsaturated organic compounds February 8, 2005
The present invention relates to a process for the metathesis reaction of unsaturated organic compounds.
6632043 Connection coupling for plate-shaped microcomponents October 14, 2003
A connection coupling forms a line connection for liquid or gaseous substances to microcomponents (1) in platelet form. A coupling body (2), which is substantially U-shaped in cross section, accommodates the edge of the plate-like microcomponent (1) between an upper limb plate (3), which
6602876 Adhesion receptor antagonists August 5, 2003
Compounds of the formula I ##STR1##wherein R.sup.1, R.sup.2 and R.sup.3 have the meanings defined herein, and also their physiologically acceptable salts, inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporoses
6492384 Imidazo (4,5-C) pyridine-4-one derivatives with factor XA inhibiting effect December 10, 2002
##STR1##The invention relates to novel compounds of formula (I), wherein R, R.sup.1, R.sup.2, R.sup.3, n and p have the meaning defined in claim 1. Compounds are inhibitors of clotting factor Xa and can be used for the prophylaxis and/or therapy of thrombo-embolic disorders.
6492368 Benzamidine derivatives as factor XA inhibitors December 10, 2002
Novel compounds of the formula I ##STR1##in which X, Y, R.sup.1, R.sup.2 and R.sup.3 are as defined in Patent Claim 1 are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders.
6488315 Coupling for microcomponents December 3, 2002
A coupling for microcomponents has several essentially plane-parallel plates with line connections for delivering and discharging liquid or gaseous components. The line connections are mounted on a connection block which protrudes through openings in the plates with fixing segments that
6455529 Adhesion receptor antagonists September 24, 2002
Compounds of the formula I ##STR1##in which R.sup.1, R.sup.2 and R.sup.3 have the stated meanings, and their physiologically acceptable salts, inhibit the binding of fibrinogen to the corresponding receptor and can be used for the treatment of thromboses, osteoporoses, oncoses, strok
6380430 Biphenyl derivatives April 30, 2002
Novel compounds of the formula I ##STR1##in whichX, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meaning indicated in Patent Claim 1,are inhibitors of the coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders.
6204280 Adhesion receptor antagonists March 20, 2001
Compounds of the formula I ##STR1##wherein R.sup.1, R.sup.2 and R.sup.3 have the meanings defined herein, and also their physiologically acceptable salts, inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporoses
6153627 Chroman derivatives November 28, 2000
Chroman derivatives of the formula I ##STR1## wherein R.sup.1 to R.sup.8 have the meanings defined herein, and their salts have an effect on the cardiovascular system.
6040308 Chroman derivatives March 21, 2000
Chroman derivatives of the formula I ##STR1## wherein R.sup.1 to R.sup.8 have the meanings defined herein, and their salts have an effect on the cardiovascular system.
6028090 Adhesion receptor antagonists III February 22, 2000
Novel oxazolidinone derivatives of the formula I ##STR1## in which R.sup.1 is a phenyl radical which is unsubstituted or is monosubstituted by CN, H.sub.2 N--CH.sub.2 --, A.sub.2 N--CH.sub.2 --, H.sub.2 N--C(.dbd.NH)--, H.sub.2 N--C(.dbd.NH)--NH--, H.sub.2 N--C(.dbd.NH)--NH--CH.s
5776937 Adhesion receptor antagonists July 7, 1998
Compounds of the formula I ##STR1## wherein R.sup.1 and Y have the meanings indicated, and also their physiologically acceptable salts, inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporoses, oncoses, apop
5723480 Adhesion receptor antagonists III March 3, 1998
Novel oxazolidinone derivatives of the formula I ##STR1## in which R.sup.1 is a phenyl radical which is unsubstituted or is monosubstituted by CN, H.sub.2 N--CH.sub.2 --, A.sub.2 N--CH.sub.2 --, H.sub.2 N--C(.dbd.NH)--, H.sub.2 N--C(.dbd.NH)--NH--, H.sub.2 N--C(.dbd.NH)--NH--CH.s
5627197 Adhesion receptor antagonists May 6, 1997
Compounds of the formula I ##STR1## wherein R.sup.1 and Y have the meanings indicated herein, and also their physiologically acceptable salts, inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporoses, oncose
5614535 Adhesion receptor antagonists March 25, 1997
Compounds of the formula I ##STR1## in which R.sup.1 and X have the meanings herein defined, their physiologically unobjectionable salts and/or solvates inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporos
5614531 Adhesion receptor antagonists March 25, 1997
Compounds of the formula I ##STR1## and the corresponding 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives, their physiologically acceptable salts and/or solvates, inhibit the binding of fibrinogen to the corresponding receptor and can be used for the treatment of thromboses,
5561148 Adhesion receptor antagonists III October 1, 1996
Novel oxazolidinone derivatives of the formula I ##STR1## in which R.sup.1 is a phenyl radical which is unsubstituted or is monosubstituted by CN, H.sub.2 N--CH.sub.2 --, A.sub.2 N--CH.sub.2 --, H.sub.2 N--C(.dbd.NH)--, H.sub.2 N--C(.dbd.NH)--NH--, H.sub.2 N--C(.dbd.NH)--NH--CH.s
5532255 Adhesion receptor antagonists July 2, 1996
Compounds of the formula ##STR1## in which R.sup.1, X and Y have the meanings defined herein, and their salts, inhibit the binding of fibrinogen to the fibrinogen receptor and can be used for treating thrombosis, stroke, cardiac infarction, inflammations, arteriosclerosis, osteop
5387587 Chroman derivatives February 7, 1995
Chroman derivatives of the formula I ##STR1## wherein R.sup.1 to R.sup.8 have the meanings defined herein, and their salts have an effect on the cardiovascular system.










 
 
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