| Patent Number |
Title Of Patent |
Date Issued |
| 5935940 |
Compositions and methods for modulating growth of a tissue in a mammal |
August 10, 1999 |
| Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low solubility and are applied directly |
| 5902799 |
Methods of modulating tissue growth and regeneration |
May 11, 1999 |
| Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low solubility and are applied directly |
| 5874419 |
Compositions and methods for modulating growth of a tissue in a mammal |
February 23, 1999 |
| Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low solubility and are applied directly |
| 5846954 |
Cyclodextrin compounds and methods of making and use thereof |
December 8, 1998 |
| The present invention provides polyanionic, substituted CDs having cellular growth modulating-activity. The invention further provides CDs having anionic groups on one side of the CD molecule. Therapeutic methods for using, as well as methods of making the CD compounds of the invention, |
| 5843920 |
Anionic saccharides for extraction of anti-angiogenic protein from cartilage |
December 1, 1998 |
| Anti-angiogenic protein composition can be prepared simply and efficiently by contacting cartilage particles containing the protein together with an electrolyte solution and an oligosaccharide bearing a minimum number of anionic substituents per sugar unit, to extract the anti-angiogenic |
| 5840713 |
Therapy for tissue membrane insufficiency |
November 24, 1998 |
| Disclosed are methods of therapy applicable to pathologies that involve loss of integrity of tissue and organ membranes that lead to abnormal permeation of proteinic and other agents and their elimination or penetration of other anatomical functions. Such deficiencies are associated |
| 5760015 |
Cyclodextrin compounds and methods of making and use thereof |
June 2, 1998 |
| The present invention provides polyanionic, substituted CDs having cellular growth modulating activity. The invention further provides CDs having anionic groups on one side of the CD molecule. Therapeutic methods for using, as well as methods of making the CD compounds of the invention, |
| 5658894 |
Compositions for inhibiting restenosis |
August 19, 1997 |
| Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low solubility and are applied directly |
| 5441944 |
Substituted cyclodextrin sulfates and their uses as growth modulating agents |
August 15, 1995 |
| The invention relates to highly water soluble substituted .alpha.-, .beta.- or .gamma.-cyclodextrin sulfates associated with a physiologically acceptable cation. Pathological or otherwise undesirable cell or tissue growth in mammals, including humans, is inhibited by administering theret |