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Inventor:
Wang; Tao
Address:
Springfield, NJ
No. of patents:
9
Patents:












Patent Number Title Of Patent Date Issued
8273790 Exo-selective synthesis of himbacine analogs September 25, 2012
This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. T
8258319 Exo- and diastereo- selective synthesis of himbacine analogs September 4, 2012
This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by th
8138180 Exo-selective synthesis of himbacine analogs March 20, 2012
This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. T
7989653 Exo- and diastereo-selective syntheses of himbacine analogs August 2, 2011
This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by th
7772276 Exo-selective synthesis of himbacine analogs August 10, 2010
This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. T
7678948 Synthesis of 3-(5-nitrocyclohex-1-enyl) acrylic acid and esters thereof March 16, 2010
This application discloses provides a process for the introduction of nitro-group functionality into a compound which contains also a site of unsaturation and/or oxygen functionality by direct (one step) oxidation of an oxime functional group mediated by a molybdenum VI/VII peroxo co
7605275 Exo- and diastereo- selective syntheses of himbacine analogs October 20, 2009
This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by th
7553987 Synthesis of 3-(5-nitrocyclohex-1-enyl) acrylic acid and esters thereof June 30, 2009
This application discloses provides a process for the introduction of nitro-group functionality into a compound which contains also a site of unsaturation and/or oxygen functionality by direct (one step) oxidation of an oxime functional group mediated by a molybdenum VI/VII peroxo co
7541471 Synthesis of himbacine analogs June 2, 2009
The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield o










 
 
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