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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Wada; H. Garrett
Address:
Atherton, CA
No. of patents:
14
Patents:












Patent Number Title Of Patent Date Issued
8216852 Channel cross-section geometry to manipulate dispersion rates July 10, 2012
The present invention provides novel methods for controlling/manipulating materials flowing in a fluidic device. In particular, the methods of the invention create and utilize differences between dispersion rates and/or average velocity of materials in order to manipulate the materials.
7754150 Microfluidic analytic detection assays, devices, and integrated systems July 13, 2010
Methods of detecting a component of interest, such as a protein, in a microfluidic system are provided. The methods include the use of a component-binding moiety specific to the component of interest, such as an antibody, to detect the component of interest. Also included are microfl
6989128 Apparatus for continuous liquid flow in microscale channels using wicking January 24, 2006
Apparatus and methods for modulating flow rates in microfluidic devices are provided. The methods involve modulating downstream pressure in the device to change the flow rate of materials in an upstream region of the device. Such methods include electrokinetic injection or withdrawal of
6979553 Use of Nernstein voltage sensitive dyes in measuring transmembrane voltage December 27, 2005
Transmembrane potential measurement methods using cationic dyes, and anionic dyes are provided. Compositions of the cationic and anionic dyes and microfluidic systems which include the dyes and membranes are provided in conjunction with processing elements for transmembrane potential
6759191 Use of nernstein voltage sensitive dyes in measuring transmembrane voltage July 6, 2004
Transmembrane potential measurement methods using cationic dyes, and anionic dyes are provided. Compositions of the cationic and anionic dyes and microfluidic systems which include the dyes and membranes are provided in conjunction with processing elements for transmembrane potential
6649358 Microscale assays and microfluidic devices for transporter, gradient induced, and binding activi November 18, 2003
Methods of monitoring transporter activity, gradient induced activity, and binding activity in microscale systems, as well as corresponding microscale devices, systems and kits are provided.
6613581 Microfluidic analytic detection assays, devices, and integrated systems September 2, 2003
Methods of detecting a component of interest, such as a protein, in a microfluidic system are provided. The methods include the use of a component-binding moiety specific to the component of interest, such as an antibody, to detect the component of interest. Also included are microfl
6592821 Focusing of microparticles in microfluidic systems July 15, 2003
Methods and systems for particle focusing to increase assay throughput and sensitivity in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Methods of sorting members of particle
6537771 Use of nernstein voltage sensitive dyes in measuring transmembrane voltage March 25, 2003
Transmembrane potential measurement methods using cationic dyes, and anionic dyes are provided. Compositions of the cationic and anionic dyes and microfluidic systems which include the dyes and membranes are provided in conjunction with processing elements for transmembrane potential
6529835 High throughput methods, systems and apparatus for performing cell based screening assays March 4, 2003
Methods for determining a function of cells, which comprises a suspension of cells flowing along a first fluid channel. The cells have a first detectable property associated therewith, and wherein the cells produce a second detectable property upon activation of the function of the cells
6506609 Focusing of microparticles in microfluidic systems January 14, 2003
Methods and systems for particle focusing to increase assay throughput in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Methods of sorting members of particle populations,
6416642 Method and apparatus for continuous liquid flow in microscale channels using pressure injection, July 9, 2002
Apparatus and methods for modulating flow rates in microfluidic devices are provided. The methods involve modulating downstream pressure in the device to change the flow rate of materials in an upstream region of the device. Such methods include electrokinetic injection or withdrawal of
6379884 Methods and systems for monitoring intracellular binding reactions April 30, 2002
Intracellular binding reactions, and particularly DNA/DNA binding protein reactions are detected in situ, using intracellular fluorescence polarization detection. The methods comprise providing a biological cell having at least a first component of a binding reaction disposed therein.
5632982 Cytotoxic enhancement of TNF with copper May 27, 1997
Copper chelates serve as cytotoxic agents in conjunction with a surface membrane protein receptor internalizing agent, particularly TNF, which has independent cytotoxic activity, for use against target cells. By employing concentrations of the two agents, where the agents have substantia










 
 
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