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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Van Antwerp; William Peter
Address:
Valencia, CA
No. of patents:
13
Patents:












Patent Number Title Of Patent Date Issued
6852694 Stabilized insulin formulations February 8, 2005
The present invention is directed to stabilized insulin composition comprising a mixture of insulin species such as insulin and an insulin analog. As disclosed herein, insulin compositions comprising a mixture of insulin and insulin analog species form heterodimeric complexes having a
6804544 Detection of biological molecules using chemical amplification and optical sensors October 12, 2004
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and b
6784274 Hydrophilic, swellable coatings for biosensors August 31, 2004
Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are provided. The surface coatings are compositions which are biocompatible and are capable of wa
6766183 Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers July 20, 2004
Fluorescent biosensor molecules, fluorescent biosensors and systems, as well as methods of making and using these biosensor molecules and systems are described. Embodiments of these biosensor molecules exhibit fluorescence emission at wavelengths greater than about 650 nm. Typical bi
6750311 Detection of biological molecules using boronate-based chemical amplification and optical sensor June 15, 2004
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and b
6734162 Mixed buffer system for stabilizing polypeptide formulations May 11, 2004
The present invention is a pharmaceutical composition for polypeptide which are not stably soluble. A preferred polypeptide is monomeric insulin and a preferred formulation consists of a TRIS-phosphate combination buffer, zinc; a phenolic preservative and an isotonicity agent such as gly
6462162 Hydrophilic, swellable coatings for biosensors October 8, 2002
Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are provided. The surface coatings are compositions which are biocompatible and are capable of wa
6443942 Medication device with protein stabilizing surface coating September 3, 2002
The present invention provides medical devices such as medication infusion pumps having internal surfaces that are treated to inhibit protein denaturation. In accordance with the invention, hydrophilic internal surfaces and related coating methods are provided to reduce or eliminate
6319540 Detection of biological molecules using chemical amplification and optical sensors November 20, 2001
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and b
6011984 Detection of biological molecules using chemical amplification and optical sensors January 4, 2000
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and b
6002954 Detection of biological molecules using boronate-based chemical amplification and optical sensor December 14, 1999
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and b
5786439 Hydrophilic, swellable coatings for biosensors July 28, 1998
Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are provided. The surface coatings are compositions which are biocompatible and are capable of wa
5777060 Silicon-containing biocompatible membranes July 7, 1998
Biocompatible membranes for use with biosensors are provided. The membranes are polymers which can be prepared from (a) a diisocyanate, (b) a hydrophilic polymer, (c) a siloxane polymer having functional groups at the chain termini, and optionally, (d) a chain extender.










 
 
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