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Inventor:
Unger; Liliane
Address:
Ludwigshafen, DE
No. of patents:
61
Patents:


1 2


Patent Number Title Of Patent Date Issued
7601730 Carboxylic acid derivatives, their preparation and use October 13, 2009
Carboxylic acid derivatives ##STR00001## where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
7582647 Carboxylic acid derivatives, their preparation and use September 1, 2009
Carboxylic acid derivatives ##STR00001## where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
7465744 Triazole compounds and the therapeutic use thereof December 16, 2008
The invention relates to triazole compounds of general formula (I), wherein A, B, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meaning cited in claim 1. The invention also relates to a pharmaceutical agent containing at least one compound of general formula (I) in addition to the u
7320979 N-[(piperazinyl)hetaryl]arylsulfonamide compounds January 22, 2008
The invention relates to N-[(piperazinyl)hetaryl]arylsulfonamide compounds of the general formula I ##STR00001## in which Q is a bivalent, 6-membered heteroaromatic radical which possesses 1 or 2 N atoms as ring members and which optionally carries one or two substituents R.sup.a wh
7119097 Carboxylic acid derivatives, their preparation and their use October 10, 2006
A compound of the formula ##STR00001## pharmaceutically acceptable salts and enantiomers thereof and pharmaceutical compositions containing this compound, its pharmaceutically acceptable salts and enantiomers are claimed.
7109205 Carboxylic acid derivatives, their preparation and use September 19, 2006
Carboxylic acid derivatives ##STR00001## where R R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
6686369 .alpha.-hydrdroxylic acid derivatives, their production and use February 3, 2004
The present invention relates to carboxylic acid derivatives of the formula ##STR1##where the radicals have the meanings stated in the description, to the preparation of these compounds and to their use as drugs.
6670367 Azinyloxy, and phenoxy-diaryl-carboxylic acid derivatives, their preparation and use as mixed ET December 30, 2003
The invention relates to carboxylic acid derivatives of the formula I ##STR1##where the radicals have the meanings stated in the description, and to their use as drugs.
6610691 Carboxylic acid derivatives, their production and use August 26, 2003
The invention relates to carboxylic acid derivatives of the formula ##STR1##where the radicals have the meanings defined in the description, to the preparation of these compounds and to their use as drugs.
6602867 Triazole compounds with dopamine-D3-receptor affinity August 5, 2003
Triazole compounds of the following formula ##STR1##where R.sup.1, R.sup.2, A and B have the meanings given in the description are described. The compounds according to the invention possess a high affinity for the dopamine D.sub.3 receptor and can therefore be used for treating dise
6600043 Carboxylic acid derivatives, their preparation and use July 29, 2003
Carboxylic acid derivatives ##STR1##where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
6583166 Triazole compounds with dopamine-D3-receptor affinity June 24, 2003
The invention relates to triazole compounds of formula (I), in which R.sup.1, R.sup.2, A and B have the meanings given in the description. The compounds provided for in the invention have a high affinity for the dopamine-D.sub.3 -receptor and can therefore be used for the treatment of
6579892 Triazole compounds with dopamine-D3-receptor affinity June 17, 2003
Triazole compounds of the following formula ##STR1##where R.sup.1, R.sup.2, A and B have the meanings given in the description are described. The compounds according to the invention possess a high affinity for the dopamine D.sub.3 receptor and can therefore be used for treating dise
6509341 Carboxylic acid derivatives, carrying amido side-chains; production and use as endothelin recept January 21, 2003
The invention relates to carboxylic acid derivatives of formula (I), wherein the substituents have the meaning as commented in the description. It also relates to the production and use of same as endothelin receptor antagonists.
6472392 Triazole compounds and the use thereof as dopamine-D3 -ligands October 29, 2002
Triazole compounds of the following formula: ##STR1##where Ar.sup.1, A, B and Ar.sup.2 have the meanings given in the description, possess a high affinity for the dopamine D.sub.3 receptor and can therefore be used for treating diseases which respond to dopamine D.sub.3 ligands.
6458821 N-substituted azabicycloheptane derivatives, production and use thereof October 1, 2002
Compounds of the formula ##STR1##in which R.sup.1, R.sup.2 and R.sup.3 have the meanings stated in the description, are described.The novel substances are suitable for controlling diseases.
6448248 Heterocyclic carboxylic acid derivatives, the production and use thereof as endothelin receptor September 10, 2002
The present invention relates to carboxylic acid derivatives of the formula I ##STR1##where the substituents have the meanings explained in the description, and to preparation and use as endothelin receptor antagonists.
6444674 Substituted pyrimidine compounds and the use thereof September 3, 2002
The present invention relates to the use of pyrimidine compounds of the following formula: ##STR1##where R.sup.1, R.sup.2, R.sup.3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 recep
6440975 Amino acid derivatives, the preparation and use thereof as endothelin antagonists August 27, 2002
The invention relates to amino acid derivatives of the formula I ##STR1##where the radicals have the meanings stated in the description, and to the use thereof as drugs.
6403593 Triazole compounds and the use thereof June 11, 2002
The present invention relates to triazole compounds of the following formula: ##STR1##where R.sup.1, R.sup.2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 receptor and can therefore be
6387912 Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia May 14, 2002
Use of pyrimidine derivatives of the formula I ##STR1##where the substituents are as defined in the description, and of their physiologically tolerated salts for producing medicaments for the prophylaxis and treatment of cerebral ischemia and strokes.
6358983 Heterocyclically substituted .alpha.-hydroxycarboxylic acid derivatives, method for producing th March 19, 2002
The present invention relates to carboxylic acid derivatives of the formula I ##STR1##the substituents having the meanings explained in the description, preparation and use as endothelin receptor antagonists.
6352981 Substituted AZA- and diazacycloheptane and -cyclooctane March 5, 2002
Aza- and diazacyclohexane and -cyclooctane compounds of the following formula:where Ar.sup.1, A, B and Ar.sup.2 have the meanings stated in the description have a high affinity for the dopamine D.sub.3 receptor and can therefore be used to treat disorders which respond to dopamine D.sub.
6342604 Substitute pyrimidine compounds and the use thereof January 29, 2002
The present invention relates to the use of pyrimidine compounds of the following formula: ##STR1##wherein R.sup.1, R.sup.2, R.sup.3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 rec
6300354 N-substituted azabicycloheptane derivatives, production and use thereof October 9, 2001
Compounds of the formula I: ##STR1##in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings stated in the description, are described.The novel compounds are suitable for controlling diseases.
6214822 Substituted aza and diazacycloheptane and cyclooctane compounds and their use April 10, 2001
Aza- and diazacyclohexane and -cyclooctane compounds of the following formula:where Ar.sup.1, A, B and Ar.sup.2 have the meanings stated in the description have a high affinity for the dopamine D.sub.3 receptor and can therefore be used to treat disorders which respond to dopamine D.sub.
6197958 Carboxylic acid derivatives, their preparation and use March 6, 2001
Carboxylic acid derivatives ##STR1##where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
6124294 Triazole compounds and the use thereof September 26, 2000
The present invention relates to triazole compounds of the following formula: where R.sup.1, R.sup.2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat
6103732 Carboxylic acid derivatives, their production and use August 15, 2000
Carboxylic acid derivatives of the formula I ##STR1## where the radicals have the meanings stated in the description, and the preparation of these agreements [sic] and their use as drugs are described.
6090807 Use of heterocyclic compounds July 18, 2000
The present invention relate to the use of heterocyclic compounds of the following formula:where Het, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 receptor and can therefore be used to trea
6028073 N-substituted 3-azabicyclo (3.2.0)heptane derivatives useful as neuroleptics February 22, 2000
N-substitued 3-azabicyclo[3.2.0]heptane derivatives of formula (I) ##STR1## in which R.sup.1, R.sup.2, A, X, Y and Z have the meanings given in the description, their method of preparation and their use as pharmacological agents.
6004988 Carboxylic acid derivatives, their preparation and their use December 21, 1999
Carboxylic acid derivatives of the formula I ##STR1## here R.sup.1 is a tetrazole [sic], nitrile [sic], a group COOH or a radical which can be hydrolyzed to COOH, and the other substituents have the meaning explained in the description.
5969134 Carboxylic acid derivatives, their preparation and use October 19, 1999
Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
5958923 Use of thiazole and thiadiazole compounds September 28, 1999
The present invention relates to the use of thiazole and thiadiazole compounds of the following formula: ##STR1## where R.sup.1, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 recepto
5932730 Carboxylic acid derivatives, their preparation and use August 3, 1999
Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
5908844 N-substituted azabicycloalkane derivatives, their preparation and use June 1, 1999
Compounds of the formula I ##STR1## where B, R.sup.1, R.sup.2, n, R.sup.3, A, X, Y and Z have the meanings stated in the description, and their preparation are described. The novel ompounds are suitable for controlling diseases.
5840722 Use of carboxylic acid derivatives as drugs November 24, 1998
A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I ##STR1##
5753690 N-substituted azobicycloheptane derivatives, the preparation and use thereof May 19, 1998
A compound of the formula ##STR1## in which A, R.sup.1 and n have the meanings stated in the description are described. The novel compounds are suitable for controlling diseases.
5703091 N-substituted azabicycloalkane derivatives, their preparation and use December 30, 1997
Compounds of the formula I ##STR1## where B, R.sup.1, R.sup.2, n and A have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.
5693637 Bicycle derivatives, their preparation and use December 2, 1997
The description relates to bicyclene derivatives of formula (I) in which A, B, D, E, G, K, L, R.sup.1, R.sup.2, Z.sup.1 and Z.sup.2 have the meanings given in the description, and their production. These compounds are suitable for treating diseases. ##STR1##
5616705 N-substituted azabicycloheptane derivatives, their preparation and use April 1, 1997
Compounds of the formula I ##STR1## where the substituents have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.
5521209 N-substituted azabicyclo[3.2.0]heptane derivatives as neuroleptics, the preparation and use ther May 28, 1996
Compounds of the formula I ##STR1## in which the substituents have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
5512584 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof April 30, 1996
Compounds of the formula ##STR1## where A-B-D, R.sup.1, R.sup.2 and R.sup.3 have the meanings stated in the description, and their preparation are described. The compounds are suitable for controlling diseases.
5424330 Benzofurancarboxamides having basic substituents, the preparation thereof, and therapeutic agent June 13, 1995
Benzofurancarboxamides having basic substituents, of the formula I ##STR1## in which R.sup.1 and X have the meanings stated in the description, a process for the preparation thereof, and therapeutic agents containing them.
5424312 Aminoalkyl-substituted 2-amino-1,3,4-thiadiazoles, the preparation and use thereof June 13, 1995
Aminoalkyl-substituted 2-amino-1,3,4-thiadiazoles of the formula ##STR1## where n and A have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases.
5418235 Aminoalkyl-substituted 5-mercaptothiazoles, the preparation and use thereof May 23, 1995
Aminoalkyl-substituted 5-mercaptothiazoles of the formula ##STR1## where R.sup.1, n and A have the meanings stated in the description, and the preparation thereof are described.The compounds are suitable for controlling diseases.
5401762 Aminoalkyl-substituted thiazolin-2-ones, the preparation and use thereof March 28, 1995
Aminoalkyl-substituted thiazolin-2-one derivatives of the formula ##STR1## where n and A have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases.
5401743 Aminoalkyl-substituted 2-amino-5-mercaptothiadiazoles the preparation and use thereof March 28, 1995
Aminoalkyl-substituted 2-amino-5-mercapto-1,3,4-thiadiazole derivatives of the formula ##STR1## where A and n have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases.
5356901 Benzofurancarboxamides having basic substituents, the preparation thereof, and therapeutic agent October 18, 1994
Benzofurancarboxamides having basic substituents, of the formula I ##STR1## in which R.sup.1 and X have the meanings stated in the description, a process for the preparation thereof, and therapeutic agents containing them.
5342853 Method of using nor-verapamil and nor-gallopamil as anti-arteriosclerotics August 30, 1994
The use of nor-verapamil and nor-gallopamil and the salts thereof with physiologically tolerated acids is disclosed for the preparation of drugs with antiarteriosclerotic properties.
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