| Patent Number |
Title Of Patent |
Date Issued |
| 7601730 |
Carboxylic acid derivatives, their preparation and use |
October 13, 2009 |
| Carboxylic acid derivatives ##STR00001## where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. |
| 7582647 |
Carboxylic acid derivatives, their preparation and use |
September 1, 2009 |
| Carboxylic acid derivatives ##STR00001## where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. |
| 7465744 |
Triazole compounds and the therapeutic use thereof |
December 16, 2008 |
| The invention relates to triazole compounds of general formula (I), wherein A, B, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meaning cited in claim 1. The invention also relates to a pharmaceutical agent containing at least one compound of general formula (I) in addition to the u |
| 7320979 |
N-[(piperazinyl)hetaryl]arylsulfonamide compounds |
January 22, 2008 |
| The invention relates to N-[(piperazinyl)hetaryl]arylsulfonamide compounds of the general formula I ##STR00001## in which Q is a bivalent, 6-membered heteroaromatic radical which possesses 1 or 2 N atoms as ring members and which optionally carries one or two substituents R.sup.a wh |
| 7119097 |
Carboxylic acid derivatives, their preparation and their use |
October 10, 2006 |
| A compound of the formula ##STR00001## pharmaceutically acceptable salts and enantiomers thereof and pharmaceutical compositions containing this compound, its pharmaceutically acceptable salts and enantiomers are claimed. |
| 7109205 |
Carboxylic acid derivatives, their preparation and use |
September 19, 2006 |
| Carboxylic acid derivatives ##STR00001## where R R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. |
| 6686369 |
.alpha.-hydrdroxylic acid derivatives, their production and use |
February 3, 2004 |
| The present invention relates to carboxylic acid derivatives of the formula ##STR1##where the radicals have the meanings stated in the description, to the preparation of these compounds and to their use as drugs. |
| 6670367 |
Azinyloxy, and phenoxy-diaryl-carboxylic acid derivatives, their preparation and use as mixed ET |
December 30, 2003 |
| The invention relates to carboxylic acid derivatives of the formula I ##STR1##where the radicals have the meanings stated in the description, and to their use as drugs. |
| 6610691 |
Carboxylic acid derivatives, their production and use |
August 26, 2003 |
| The invention relates to carboxylic acid derivatives of the formula ##STR1##where the radicals have the meanings defined in the description, to the preparation of these compounds and to their use as drugs. |
| 6602867 |
Triazole compounds with dopamine-D3-receptor affinity |
August 5, 2003 |
| Triazole compounds of the following formula ##STR1##where R.sup.1, R.sup.2, A and B have the meanings given in the description are described. The compounds according to the invention possess a high affinity for the dopamine D.sub.3 receptor and can therefore be used for treating dise |
| 6600043 |
Carboxylic acid derivatives, their preparation and use |
July 29, 2003 |
| Carboxylic acid derivatives ##STR1##where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. |
| 6583166 |
Triazole compounds with dopamine-D3-receptor affinity |
June 24, 2003 |
| The invention relates to triazole compounds of formula (I), in which R.sup.1, R.sup.2, A and B have the meanings given in the description. The compounds provided for in the invention have a high affinity for the dopamine-D.sub.3 -receptor and can therefore be used for the treatment of |
| 6579892 |
Triazole compounds with dopamine-D3-receptor affinity |
June 17, 2003 |
| Triazole compounds of the following formula ##STR1##where R.sup.1, R.sup.2, A and B have the meanings given in the description are described. The compounds according to the invention possess a high affinity for the dopamine D.sub.3 receptor and can therefore be used for treating dise |
| 6509341 |
Carboxylic acid derivatives, carrying amido side-chains; production and use as endothelin recept |
January 21, 2003 |
| The invention relates to carboxylic acid derivatives of formula (I), wherein the substituents have the meaning as commented in the description. It also relates to the production and use of same as endothelin receptor antagonists. |
| 6472392 |
Triazole compounds and the use thereof as dopamine-D3 -ligands |
October 29, 2002 |
| Triazole compounds of the following formula: ##STR1##where Ar.sup.1, A, B and Ar.sup.2 have the meanings given in the description, possess a high affinity for the dopamine D.sub.3 receptor and can therefore be used for treating diseases which respond to dopamine D.sub.3 ligands. |
| 6458821 |
N-substituted azabicycloheptane derivatives, production and use thereof |
October 1, 2002 |
| Compounds of the formula ##STR1##in which R.sup.1, R.sup.2 and R.sup.3 have the meanings stated in the description, are described.The novel substances are suitable for controlling diseases. |
| 6448248 |
Heterocyclic carboxylic acid derivatives, the production and use thereof as endothelin receptor |
September 10, 2002 |
| The present invention relates to carboxylic acid derivatives of the formula I ##STR1##where the substituents have the meanings explained in the description, and to preparation and use as endothelin receptor antagonists. |
| 6444674 |
Substituted pyrimidine compounds and the use thereof |
September 3, 2002 |
| The present invention relates to the use of pyrimidine compounds of the following formula: ##STR1##where R.sup.1, R.sup.2, R.sup.3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 recep |
| 6440975 |
Amino acid derivatives, the preparation and use thereof as endothelin antagonists |
August 27, 2002 |
| The invention relates to amino acid derivatives of the formula I ##STR1##where the radicals have the meanings stated in the description, and to the use thereof as drugs. |
| 6403593 |
Triazole compounds and the use thereof |
June 11, 2002 |
| The present invention relates to triazole compounds of the following formula: ##STR1##where R.sup.1, R.sup.2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 receptor and can therefore be |
| 6387912 |
Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia |
May 14, 2002 |
| Use of pyrimidine derivatives of the formula I ##STR1##where the substituents are as defined in the description, and of their physiologically tolerated salts for producing medicaments for the prophylaxis and treatment of cerebral ischemia and strokes. |
| 6358983 |
Heterocyclically substituted .alpha.-hydroxycarboxylic acid derivatives, method for producing th |
March 19, 2002 |
| The present invention relates to carboxylic acid derivatives of the formula I ##STR1##the substituents having the meanings explained in the description, preparation and use as endothelin receptor antagonists. |
| 6352981 |
Substituted AZA- and diazacycloheptane and -cyclooctane |
March 5, 2002 |
| Aza- and diazacyclohexane and -cyclooctane compounds of the following formula:where Ar.sup.1, A, B and Ar.sup.2 have the meanings stated in the description have a high affinity for the dopamine D.sub.3 receptor and can therefore be used to treat disorders which respond to dopamine D.sub. |
| 6342604 |
Substitute pyrimidine compounds and the use thereof |
January 29, 2002 |
| The present invention relates to the use of pyrimidine compounds of the following formula: ##STR1##wherein R.sup.1, R.sup.2, R.sup.3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 rec |
| 6300354 |
N-substituted azabicycloheptane derivatives, production and use thereof |
October 9, 2001 |
| Compounds of the formula I: ##STR1##in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings stated in the description, are described.The novel compounds are suitable for controlling diseases. |
| 6214822 |
Substituted aza and diazacycloheptane and cyclooctane compounds and their use |
April 10, 2001 |
| Aza- and diazacyclohexane and -cyclooctane compounds of the following formula:where Ar.sup.1, A, B and Ar.sup.2 have the meanings stated in the description have a high affinity for the dopamine D.sub.3 receptor and can therefore be used to treat disorders which respond to dopamine D.sub. |
| 6197958 |
Carboxylic acid derivatives, their preparation and use |
March 6, 2001 |
| Carboxylic acid derivatives ##STR1##where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. |
| 6124294 |
Triazole compounds and the use thereof |
September 26, 2000 |
| The present invention relates to triazole compounds of the following formula: where R.sup.1, R.sup.2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat |
| 6103732 |
Carboxylic acid derivatives, their production and use |
August 15, 2000 |
| Carboxylic acid derivatives of the formula I ##STR1## where the radicals have the meanings stated in the description, and the preparation of these agreements [sic] and their use as drugs are described. |
| 6090807 |
Use of heterocyclic compounds |
July 18, 2000 |
| The present invention relate to the use of heterocyclic compounds of the following formula:where Het, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 receptor and can therefore be used to trea |
| 6028073 |
N-substituted 3-azabicyclo (3.2.0)heptane derivatives useful as neuroleptics |
February 22, 2000 |
| N-substitued 3-azabicyclo[3.2.0]heptane derivatives of formula (I) ##STR1## in which R.sup.1, R.sup.2, A, X, Y and Z have the meanings given in the description, their method of preparation and their use as pharmacological agents. |
| 6004988 |
Carboxylic acid derivatives, their preparation and their use |
December 21, 1999 |
| Carboxylic acid derivatives of the formula I ##STR1## here R.sup.1 is a tetrazole [sic], nitrile [sic], a group COOH or a radical which can be hydrolyzed to COOH, and the other substituents have the meaning explained in the description. |
| 5969134 |
Carboxylic acid derivatives, their preparation and use |
October 19, 1999 |
| Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. |
| 5958923 |
Use of thiazole and thiadiazole compounds |
September 28, 1999 |
| The present invention relates to the use of thiazole and thiadiazole compounds of the following formula: ##STR1## where R.sup.1, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D.sub.3 recepto |
| 5932730 |
Carboxylic acid derivatives, their preparation and use |
August 3, 1999 |
| Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. |
| 5908844 |
N-substituted azabicycloalkane derivatives, their preparation and use |
June 1, 1999 |
| Compounds of the formula I ##STR1## where B, R.sup.1, R.sup.2, n, R.sup.3, A, X, Y and Z have the meanings stated in the description, and their preparation are described. The novel ompounds are suitable for controlling diseases. |
| 5840722 |
Use of carboxylic acid derivatives as drugs |
November 24, 1998 |
| A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I ##STR1## |
| 5753690 |
N-substituted azobicycloheptane derivatives, the preparation and use thereof |
May 19, 1998 |
| A compound of the formula ##STR1## in which A, R.sup.1 and n have the meanings stated in the description are described. The novel compounds are suitable for controlling diseases. |
| 5703091 |
N-substituted azabicycloalkane derivatives, their preparation and use |
December 30, 1997 |
| Compounds of the formula I ##STR1## where B, R.sup.1, R.sup.2, n and A have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases. |
| 5693637 |
Bicycle derivatives, their preparation and use |
December 2, 1997 |
| The description relates to bicyclene derivatives of formula (I) in which A, B, D, E, G, K, L, R.sup.1, R.sup.2, Z.sup.1 and Z.sup.2 have the meanings given in the description, and their production. These compounds are suitable for treating diseases. ##STR1## |
| 5616705 |
N-substituted azabicycloheptane derivatives, their preparation and use |
April 1, 1997 |
| Compounds of the formula I ##STR1## where the substituents have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases. |
| 5521209 |
N-substituted azabicyclo[3.2.0]heptane derivatives as neuroleptics, the preparation and use ther |
May 28, 1996 |
| Compounds of the formula I ##STR1## in which the substituents have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases. |
| 5512584 |
1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof |
April 30, 1996 |
| Compounds of the formula ##STR1## where A-B-D, R.sup.1, R.sup.2 and R.sup.3 have the meanings stated in the description, and their preparation are described. The compounds are suitable for controlling diseases. |
| 5424330 |
Benzofurancarboxamides having basic substituents, the preparation thereof, and therapeutic agent |
June 13, 1995 |
| Benzofurancarboxamides having basic substituents, of the formula I ##STR1## in which R.sup.1 and X have the meanings stated in the description, a process for the preparation thereof, and therapeutic agents containing them. |
| 5424312 |
Aminoalkyl-substituted 2-amino-1,3,4-thiadiazoles, the preparation and use thereof |
June 13, 1995 |
| Aminoalkyl-substituted 2-amino-1,3,4-thiadiazoles of the formula ##STR1## where n and A have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases. |
| 5418235 |
Aminoalkyl-substituted 5-mercaptothiazoles, the preparation and use thereof |
May 23, 1995 |
| Aminoalkyl-substituted 5-mercaptothiazoles of the formula ##STR1## where R.sup.1, n and A have the meanings stated in the description, and the preparation thereof are described.The compounds are suitable for controlling diseases. |
| 5401762 |
Aminoalkyl-substituted thiazolin-2-ones, the preparation and use thereof |
March 28, 1995 |
| Aminoalkyl-substituted thiazolin-2-one derivatives of the formula ##STR1## where n and A have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases. |
| 5401743 |
Aminoalkyl-substituted 2-amino-5-mercaptothiadiazoles the preparation and use thereof |
March 28, 1995 |
| Aminoalkyl-substituted 2-amino-5-mercapto-1,3,4-thiadiazole derivatives of the formula ##STR1## where A and n have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases. |
| 5356901 |
Benzofurancarboxamides having basic substituents, the preparation thereof, and therapeutic agent |
October 18, 1994 |
| Benzofurancarboxamides having basic substituents, of the formula I ##STR1## in which R.sup.1 and X have the meanings stated in the description, a process for the preparation thereof, and therapeutic agents containing them. |
| 5342853 |
Method of using nor-verapamil and nor-gallopamil as anti-arteriosclerotics |
August 30, 1994 |
| The use of nor-verapamil and nor-gallopamil and the salts thereof with physiologically tolerated acids is disclosed for the preparation of drugs with antiarteriosclerotic properties. |