| Patent Number |
Title Of Patent |
Date Issued |
| 7553965 |
5-HT.sub.7 receptor antagonists |
June 30, 2009 |
| The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some 2,2a,4,5-tetrahydro-1H-3-aza-acenaphthylen substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions com |
| 7345057 |
5-HT7 receptor antagonists |
March 18, 2008 |
| The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some some tetrahydroisoquinoline substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, a |
| 7109349 |
Process for obtaining Cizolirtine and its enantiomers |
September 19, 2006 |
| A process is described for the preparation of a precursor alcohol of Cizolirtine, (.+-.)-2-[phenyl(1-methyl-1H-pyrazol-5-yl)methoxy]-N,N-dimethylethanamine and its enantiomers. The process involves the asymmetric addition of a metalated phenyl reagent to a pyrazolcarbaldehyde in the |
| 7078531 |
Process for obtaining enantiomers of thienylazolylalcoxyethanamines |
July 18, 2006 |
| A process is described for the preparation of a precursor alcohol of (.+-.)-2-[thienyl(1-methyl-1H-pyrazol-5-yl)methoxy]-N,N-dimethyletanamine and in general for thienylazolylalcoxyethanamines and their enantiomers. The process involves asymmetric addition of a metalated thienyl reagent |
| 6979742 |
Process for obtaining enantiomers of thienylazolylalcoxyethanamines |
December 27, 2005 |
| A process is described for the preparation of a precursor alcohol of (.+-.)-2-[thienyl(1-methyl-1H-pyrazol-5-yl)methoxy]-N,N-dimethyletanamine, and more generally for thyenylazolylalcoxyethanamines and their enantiomers. The process involves the asymmetric reduction of a prochiral ke |
| 6187930 |
Resolution of amines |
February 13, 2001 |
| The procedure comprises reacting the mixture that comprises 2-[phenyl(1-methyl-1 H-pyrazole-5-yl)methoxy]-N,N-dimethylethanamine (I) with an enantiomer of an optically active acid to form a diastereoisomeric salt, separating said salt and liberating the enantiomer of said compound (I |
| 6118009 |
Process for obtaining enantiomers of cis-olirtine |
September 12, 2000 |
| The procedure comprises (a) the enantioselective reduction of a pro-chiral ketone (III) by using a reducing and agent and chiral catalyst, both boron derivatives, in an anhydrous solvent or mixture of anhydrous solvents to form an enantiomer of an alcohol (II), and (b), the alkylation of |
