A co-aptive surgical instrument has a pair of opposite facing co-aptive surfaces for grasping tissue. The co-aptive surfaces are formed with a matrix layer which is preferably of a metal such as nickel with a plurality of hard crystalline particles which are preferably a diamond grit
A composition for enhancing vascular perfusion and reperfusion in disease states, both in man and animals comprising an aqueous solution having a slightly acidic pH, and suitable for intravenous use and containing glucose, insulin and Magnesium dipotassium ethylene diamine tetraacetic