| Patent Number |
Title Of Patent |
Date Issued |
| 7626045 |
Synthesis of himbacine analogs |
December 1, 2009 |
| The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield o |
| 7605275 |
Exo- and diastereo- selective syntheses of himbacine analogs |
October 20, 2009 |
| This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by th |
| 7553987 |
Synthesis of 3-(5-nitrocyclohex-1-enyl) acrylic acid and esters thereof |
June 30, 2009 |
| This application discloses provides a process for the introduction of nitro-group functionality into a compound which contains also a site of unsaturation and/or oxygen functionality by direct (one step) oxidation of an oxime functional group mediated by a molybdenum VI/VII peroxo co |
| 7541471 |
Synthesis of himbacine analogs |
June 2, 2009 |
| The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield o |
| 7049440 |
Enantioselective process |
May 23, 2006 |
| An enantioselective process for preparing intermediates useful in the preparation of the chiral tricyclic compound of formula I ##STR00001## is disclosed. |
| 6872826 |
Stereoselective alkylation of chiral 2-methyl-4-protected piperazines |
March 29, 2005 |
| In an illustrative embodiment, the present invention describes the synthesis of the following compound and similar compounds, in high stereochemical purity by a novel stereoselective alkylation process: ##STR1## |
| 6207822 |
Process for the synthesis of azetidinones |
March 27, 2001 |
| This invention provides a process for preparing the hypocholesterolemic compound ##STR1##comprising:(a) reacting p-fluorobenzoylbutyric acid with pivaloyl chloride and acylating the product with a chiral auxiliary to obtain a ketone of formula IV: ##STR2##(b) reducing the ketone |
