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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Terahara; Akira
Address:
Hiromachi, JP
No. of patents:
9
Patents:












Patent Number Title Of Patent Date Issued
4537859 Process for preparing 3-hydroxy-ML-236B derivatives known as M-4 and M-4' August 27, 1985
Compounds of formula (I): ##STR1## (wherein OH represents OH or OH), that is to say M-4 carboxylic acid and M-4' carboxylic acid, as well as pharmaceutically acceptable salts and esters thereof and the corresponding ring-closed lactones may be prepared by contacting an ML-236B co
4517373 IsoMB-530B derivatives May 14, 1985
The 1-acyloxy-6-hydroxy-IsoMB-530B lactones of the formula (I): ##STR1## wherein R.sup.1 represents a group of the formula ##STR2## wherein R.sup.2 is a C.sub.1 -C.sub.10 alkyl group.
4479965 M-4 and IsoM-4 derivatives their preparation and compositions containing them October 30, 1984
Tetrahydro-M-4 and tetrahydro-IsoM-4 hydroxy carboxylic acids of the formula (I): ##STR1## wherein one of R.sup.1 and R.sup.2 represents a hydrogen atom and the other represents a hydroxy group which are useful for inhibiting chloresterol biosynthesis in the liver. The invention
4451481 M-4 And IsoM-4 derivatives and compositions containing them May 29, 1984
Dihydro-M-4 and dihydro-IsoM-4 are new compounds which may be prepared by the catalytic hydrogenation of M-4 or IsoM-4 respectively. They, and their salts and esters (which may be prepared by conventional salification or esterification reactions with the parent dihydro-M-4 or dihydro-Iso
4448979 ML-236B Derivatives May 15, 1984
Compounds of formula (I): ##STR1## (wherein R represents a group of formula ##STR2## and the corresponding ring-closed lactones, salts (especially alkali metal salts) and esters (especially C.sub.1 -C.sub.5 alkyl esters) thereof may be prepared by subjecting ML-236B, or ML-23
4438277 Hydronaphthalene derivatives March 20, 1984
Compounds of formula (I): ##STR1## (in which: Z represents a group of formula ##STR2## A represents a group of formula ##STR3## B represents a group of formula ##STR4## R.sup.1 represents a hydrogen atom or a methyl group; R.sup.2, R.sup.3, R.sup.4 and R.sup.6 are
4361515 Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use November 30, 1982
Compounds of formula (I): ##STR1## (in which: Z represents a group of formula ##STR2## A represents a group of formula ##STR3## B represents a group of formula ##STR4## R.sup.1 represents a hydrogen atom or a methyl group; R.sup.2, R.sup.3, R.sup.4 and R.sup.6
4346227 ML-236B Derivatives and their preparation August 24, 1982
Compounds of formula (I): ##STR1## (wherein R represents a group of formula ##STR2## and the corresponding ring-closed lactones, salts (especially alkali metal salts) and esters (especially C.sub.1 -C.sub.5 alkyl esters) thereof may be prepared by subjecting ML-236B, or ML-23
4255444 4-Hydroxy-2-pyrone derivatives having antihyperlipaemic activity March 10, 1981
4-Hydroxy-2-pyrone derivatives of formula (I): ##STR1## (wherein A represents an alkylene group which is optionally alkyl-substituted or an alkenylene group, and Z represents a substituted or unsubstituted aryl or aryloxy group) may be prepared by cyclizing an ester of formula (I










 
 
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