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Inventor:
Tamura; Masahiro
Address:
Higashimurayama, JP
No. of patents:
21
Patents:












Patent Number Title Of Patent Date Issued
8575153 Pyridine-3-carboxyamide derivative November 5, 2013
To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjogren syndrome, Behcet's disease, type I diabet
6867221 Cyclic amine compounds and pharmaceutical composition containing the same March 15, 2005
A cyclic amine compound represented by the following general formula (1): ##STR1##wherein, R.sup.1, R.sup.2 and R.sup.3 each independently represent a hydrogen atom or an alkoxy group; W.sup.1 and W.sup.2 each independently represent N or CH; X represents O, NR.sup.4, CONR.sup.4 or
6632810 Cyclic diamine compound with condensed-ring groups October 14, 2003
A cyclic diamine compound of formula (1): ##STR1## wherein R.sup.1 and R.sup.2 are individually a hydrogen atom or a methoxy group, provided R.sup.1 is a methoxy group when R.sup.2 is a hydrogen atom, or a hydrogen atom when R.sup.2 is a methoxy group; A is an oxygen atom, a sulfu
6552188 Unsymmetrical cyclic diamine compound April 22, 2003
Cyclic diamine compounds of formula (1) are disclosed: ##STR1##wherein A is (CH.sub.2).sub.n, (CH.sub.2).sub.n --CH.dbd.CH, CO--(CH.sub.2).sub.n or CO--(CH.sub.2).sub.n --CH.dbd.CH, in which n is a number of 0 to 3; Z represents a formula (2) or (3): ##STR2## in which R.sup.1,
6509329 Cyclic diamine compound with 6-membered ring groups January 21, 2003
A cyclic diamine compound of formula (1): ##STR1##wherein A is a single bond or C.ident.C; X and Y are individually CH or a nitrogen atom; m is 1 or 2; and n is a number of 1 to 5; an acid-addition salt thereof, or a hydrate thereof. The compound has excellent inhibitory effects on b
6498169 Cyclic amine compounds and pharmaceutical composition containing the same December 24, 2002
A cyclic amine compound represented by the following general formula (1): ##STR1##wherein, R.sup.1, R.sup.2 and R.sup.3 each independently represent a hydrogen atom or an alkoxy group; W.sup.1 an W.sup.2 each independently represent N or CH; X represents O, NR.sup.4, CONR.sup.4 or N
6472386 Cyclic diamine compound with 5-membered ring groups October 29, 2002
A compound of formula (1): ##STR1##wherein A is a single bond, C.ident.C, CONH or NHCO; W is a carbon atom or a nitrogen atom; X is CH, a nitrogen atom, an oxygen atom or a sulfur atom; Y is CH, CHR.sup.1, in which R.sup.1 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lo
6432957 Piperazine derivative August 13, 2002
A piperazine compound represented by formula (1): ##STR1##wherein X is --CH.sub.2 --, --C(O)-- or --CH(CH.sub.3)--; R.sup.1 is a hydrogen atom or alkyl group; and R.sup.2 is a hydrogen atom, alkyl group, hydroxyalkyl group, arylalkyl group, heteroarylalkyl group, carboxyalkyl group,
6395753 Cyclic amine compounds and pharmaceutical composition containing the same May 28, 2002
A cyclic amine compound represented by the following general formula (1): ##STR1##wherein,R.sup.1, R.sup.2 and R.sup.3 each independently represent a hydrogen atom or an alkoxy group;W.sup.1 and W.sup.2 each independently represent N or CH;X represents O, NR.sup.4, CONR.sup.4 or NR.sup.4 CO;
6337334 Pyrimidine derivatives January 8, 2002
The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: ##STR1##[wherein R.sup.1 represents a lower alkyl group; each of R.sup.2 and R.sup.3 represents H, alkyl, or alkoxy; each of R.sup.4 and R.sup.5 represents H or alky
6136848 Flavone derivative and medicine comprising the same October 24, 2000
This invention relates to a flavone derivative represented by the formula (1) or a salt thereof, and also to a medicine containing the same. ##STR1## wherein A represents H, halogen, phenyl, naphthyl, a group of the formula (2) in which X is H or halogen, B is --CH.dbd.CH--, --CH.dbd
6127360 Diamine derivatives and pharmaceutical containing the same October 3, 2000
This invention relates to a diamine derivative represented by the following formula (1) or a salt thereof. wherein R.sup.1 represents H, OH, an aralkyloxy group or a halogen atom; R.sup.2 represents H or a lower alkyl group; A represents --C(R.sup.3).dbd.CH--, --CH.dbd.N--, --N(R.sup.4)-
6121286 Tetrazole derivatives September 19, 2000
The present invention is directed to a tetrazole derivative represented by the following formula (1) or a salt thereof: ##STR1## wherein R.sup.1 and R.sup.2 independently represent a hydrogen atom, a hydroxyl group, a lower alkyl group, a substituted or unsubstituted alkoxy group
6117886 Tetrazole derivatives September 12, 2000
The present invention is directed to a tetrazole derivative represented by the following formula (1) or a salt thereof: ##STR1## wherein R.sup.1 and R.sup.2 independently represent a hydrogen atom, a hydroxyl group, a lower alkyl group, a substituted or unsubstituted alkoxy group
6107308 Piperidine derivatives August 22, 2000
The present invention is directed to a piperidine derivative represented by the following formula (1) or a salt thereof: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 individually represent hydrogen atoms, etc., Y represents ##STR2## B represents a single bond, an alkylene g
6046212 Chalcone derivatives and drugs containing the same April 4, 2000
This invention relates to chalcone derivatives represented by the following formula (1): wherein A represents a phenyl group, a quinolyl group or the like, W represents a vinylene group or the like, and R.sup.1 to R.sup.5 each independently represent a carboxyl, cyano, alkyloxycarbonyl o
6011033 Phenylene derivatives January 4, 2000
This invention relates to a phenylene derivative represented by the following formula (1) or a salt thereof and also to a medicine containing it as an effective ingredient. ##STR1## wherein R.sup.1 represents H or halogen; A represents --CH.dbd.CH--, --CH.dbd.N--, --N(R.sup.2)--,
6008224 Pyrimidine derivatives December 28, 1999
The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: ##STR1## [wherein R.sup.1 represents a lower alkyl group; each of R.sup.2 and R.sup.3 represents H, alkyl, or alkoxy; each of R.sup.4 and R.sup.5 represents H or
5885987 Phenylene derivatives March 23, 1999
This invention relates to a phenylene derivative represented by the following formula (1) or a salt thereof and also to a medicine containing it as an effective ingredient. ##STR1## wherein R.sup.1 represents H or halogen; A represents --CH.dbd.CH--, --CH.dbd.N--, --N(R.sup.2)--,
5883092 Pyrimidine derivatives as endothelin antagonists March 16, 1999
The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: ##STR1## [wherein R.sup.1 represents a hydroxyl group, a lower alkoxy group, a phenyloxy group which may have a substituent, an aralkyloxy group which may have a
5756518 Phenylene derivatives May 26, 1998
This invention relates to a phenylene derivative represented by the following formula (1) or a salt thereof and also to a medicine containing it as an effective ingredient. ##STR1## wherein R.sup.1 represents H or halogen; A represents --CH.dbd.CH--, --CH.dbd.N--, --N(R.sup.2)--,










 
 
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