| Patent Number |
Title Of Patent |
Date Issued |
| RE38624 |
Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and process for their preparation |
October 12, 2004 |
| The invention relates to new hydroxyindoles of the Formula, ##STR1##their use as inhibitors of phosphodiesterase 4 and processes for their preparation. |
| 7419987 |
7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them |
September 2, 2008 |
| 7-azaindoles inhibit phosphodiesterase 4 (PDE4). Methods for preparing these compounds are also provided. |
| 7169787 |
7-azaindoles, use thereof as phosphodiesterase 4 inhibitors and method for producing the same |
January 30, 2007 |
| The invention relates to new 7-azaindoles, their use as inhibitors of phosphodiesterase 4 and to methods for their synthesis. |
| 7161009 |
Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparati |
January 9, 2007 |
| The invention relates to new hydroxyindoles of the Formula, ##STR00001## their use as inhibitors of phosphodiesterase 4 and processes for their preparation. |
| 6919344 |
N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/i |
July 19, 2005 |
| The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immuno-suppressant/immunomodulating actions. |
| 6613794 |
Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparati |
September 2, 2003 |
| The invention relates to new hydroxyindoles of the Formula, ##STR1##their use as inhibitors of phosphodiesterase 4 and processes for their preparation. |
| 6602890 |
Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparati |
August 5, 2003 |
| The invention relates to new hydroxyindoles of the Formula, ##STR1##their use as inhibitors of phosphodiesterase 4 and processes for their preparation. |
| 6545158 |
Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparati |
April 8, 2003 |
| The invention relates to new hydroxyindoles of the Formula, ##STR1##their use as inhibitors of phosphodiesterase 4 and processes for their preparation. |
| 6545025 |
Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparati |
April 8, 2003 |
| The invention relates to nets hydroxyindoles of the Formula, ##STR1##their use as inhibitors of phosphodiesterase 4 and processes for their preparation. |
| 6465465 |
Process for the treatment of erectile dysfunction and product therefor |
October 15, 2002 |
| The invention relates to the use of pyrido[3,2-e]-pyrazinones of formula 1 as inhibitors of phosphodiesterase 5 for the treatment of erectile dysfunction (impotence). |
| 6344467 |
N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/i |
February 5, 2002 |
| The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immunosuppressant/immunomodulating actions. |
| 6251923 |
Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and process for their preparation |
June 26, 2001 |
| The invention relates to new hydroxyindoles of the Formula, ##STR1##their use as inhibitors of phosphodiesterase 4 and processes for their preparation. |
| 6008231 |
N-substituted indole-3 glyoxylamides having anti-asthmatic antiallergic and immunosuppressant/im |
December 28, 1999 |
| The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immuno-suppressant/immunomodulating actions. |
| 5965582 |
N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammato |
October 12, 1999 |
| The N-benzylindole- and benzopyrazole derivatives of the general formula 1 ##STR1## possess anti-asthmatic, anti-allergic, anti-inflammatory and immunomodulating effect and are suitable for the preparation of medicaments. |
| 5723463 |
Pyrido [3,2-E]pyrazinones with anti-asthmatic action and processes for their manufacture |
March 3, 1998 |
| The invention relates to novel pyrido[3,2-e]pyrazinones, processes for their preparation and their pharmaceutical use.The compounds have anti-asthmatic and anti-allergic effects. |
| 5721258 |
Primary and secondary neuroprotective effect of flupirtine in neurodegenerative diseases |
February 24, 1998 |
| The NMDA-antagonistic effect of flupirtine permits the preparation of medicaments for the treatment of cerebral ischemia, neurodegenerative disorders, traumatic brain and bone marrow damage, and other illnesses. |
| 5464838 |
Aminocarboxylic acid derivatives having antiallergic/antiasthmatic effect and a process for thei |
November 7, 1995 |
| 6-amino carboxylic acid derivatives having antiasthmatic and antiallergic properties which can be used for the preparation of medicaments. The compounds have the formula: ##STR1## wherein R.sub.1 and R.sub.2 represent hydrogen, a straight-chain or branched alkyl radical with 1-6 |
| 5405847 |
4,5-dihydro-4-oxo-pyrrolo[1,2-a]quinoxalinones and corresponding aza analogs and a process for t |
April 11, 1995 |
| Novel compounds of the formula ##STR1## where the phenyl ring can also contain a nitrogen atom instead of a CH group, R.sub.1 is C.sub.2 -C.sub.6 -alkenyl, C.sub.2 -C.sub.6 -alkynyl, hydroxy, C.sub.1 -C.sub.6 -alkoxy, C.sub.3 -C.sub.6 -alkenyloxy, C.sub.3 -C.sub.6 -alkynyloxy, C. |
| 5384330 |
Pharmaceutically active 1,2,4-triamino-benzene derivatives, processes for their preparation and |
January 24, 1995 |
| Pharmacologically active 1,2,4-triaminobenzene derivatives of the General Formula I: ##STR1## where the symbols R1' R2' R3' R4' R5' Ar and Alk have the following meanings:where the symbols R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, Ar and Alk have the following meanings:R.sub.1 |
| 5354750 |
Phthalazines containing an aromatic ether or thioether group in the 1-position |
October 11, 1994 |
| Pharmacologically active compounds of the General Formula ##STR1## where X is oxygen or sulphur and the radical R represents a quinuclidyl radical, an C.sub.1 -C.sub.6 -alkyl radical, a phenyl radical, a pyridyl radical, a phenyl or pyridyl radical substituted by the radicals R.sub.1 |