| Patent Number |
Title Of Patent |
Date Issued |
| 7579365 |
Indolyl-3-glyoxylic acid derivatives having antitumor action |
August 25, 2009 |
| The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents ##STR00001## and to a pharmaceutical composition having antitumor action, characterized in that it contains at least one of the compounds of the general formula 1, if |
| 7553858 |
Combination of flupirtine and tramadol |
June 30, 2009 |
| The subject of the present invention is to provide a combination of two centrally acting analgesics, flupirtine and tramadol, or their respective pharmaceutically acceptable salts for the treament of pain. |
| 7521438 |
Combination of loteprednol and .beta..sub.2-adrenoceptor agonists |
April 21, 2009 |
| The invention relates to a novel combination of a soft steroid, in particular loteprednol, and at least one .beta..sub.2 adrenoceptor agonist for the simultaneous, sequential or separate treatment of allergies and/or airway disorders, medicaments comprising the combination, processes |
| 6436924 |
Antihistamine leukotriene combinations |
August 20, 2002 |
| The invention relates to a pharmaceutical composition for the treatment of allergic rhinitis, vasomotor rhinitis, and allergic conjunctivitis, which comprises (a) a nonsedating antihistamine or a pharmaceutically acceptable salt thereof, (b) a leukotriene D.sub.4 antagonist, or a 5-lipox |
| 6251932 |
Immunophilin ligands |
June 26, 2001 |
| The invention relates to an immunophilin ligand of Formula I and having antiasthmatic, antiallergic, antirheumatic, immunosuppressant, antipsoriatic and neuroprotectant properties, ##STR1## |
| 6232327 |
Indolyl-3-glyoxylic acid derivatives having antitumor action |
May 15, 2001 |
| The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents ##STR1##and to a pharmaceutical composition having antitumor action, characterized in that it contains at least one of the compounds of the general formula 1, if appr |
| 5776932 |
1,3,5-tribsubstituted indazole derivatives, processes for preparing, and for pharmacological tre |
July 7, 1998 |
| 1,3,5-trisubstituted indazole derivatives of the formula ##STR1## wherein R1 is H, (b) a C.sub.1-6 straight or branched, substituted or unsubstituted alkyl residue, (c) a C.sub.3-7 cycloalkyl residue, (d) an unsustituted or substituted phenyl, naphthyl, anthranyl, or fluorenyl re |
| 5521178 |
Combination medication containing flupirtin and morphine for the treatment of pain and the preve |
May 28, 1996 |
| A combination medication containing flupirtin and morphine for the treatment of pain and the prevention of morphine dependence |
| 5284861 |
Pharmaceutical composition comprising flupirtine and its use to combat Parkinson disorders |
February 8, 1994 |
| Flupirtine is used for the treatment of disorders involving skeletal muscle tension. |
| 5162346 |
Pharmaceutical composition comprising flupirtine and its use to combat muscular tension |
November 10, 1992 |
| Flupirtine is used for the treatment of disorders involving skeletal muscle tension. |
| 5110814 |
Azelastine and its salts used to combat psoriasis |
May 5, 1992 |
| The use of azelastine or its therapeutically acceptable salts and the preparation of a pharmaceutical composition for the treatment of inflammatory disorders and psoriasis disorders. |
| 5021431 |
Imidazolyl alkyl guanidine derivatives, processes for their preparation and pharmaceutical prepa |
June 4, 1991 |
| New imidazolylalkyl-guanidine derivatives are described, which by virtue of their agonistic action on histamine-H.sub.2 receptors and in part also due to their additional H.sub.1 -antagonistic receptor activity can be used in the treatment of cardiac diseases, certain forms of hypertensi |
| 4946836 |
Nitrogen-containing cyclo-aliphatic compounds having an amino radical and a pyridine radical |
August 7, 1990 |
| Compounds of formula ##STR1## wherein the radicals R.sub.1 and R.sub.2 are the same or different and represent hydrogen, halogen atoms, a trifluoromethyl group, a cyano, a nitro group, an amino group, a mono-C.sub.1 -C.sub.6 -alkylamino group, a di-C.sub.1 -C.sub.6 -alkylamino gr |
| 4923858 |
Substituted 3-(n-heterocyclic)-2,6-diaminopyridines and -n-oxides |
May 8, 1990 |
| Compounds of the general formula: ##STR1## wherein the radicals R.sub.1 and R.sub.2 are the same or different and represent hydrogen or C.sub.1 -C.sub.6 -alkyl, the radicals R.sub.3 and R.sub.4 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 -alkyl, hydroxy, C. |
| 4866066 |
Thiomethylpyridine derivatives and their use for eliciting a bronchosecretolytic or mucolytic re |
September 12, 1989 |
| Thiomethylpyridine derivatives having bronchosecretolytic and mucolytic activity according to the formula: ##STR1## wherein R is a group attached in the 2-, 3- or 4-position of the pyridine ring which corresponds to the following general formula:wherein Q is a substituted or unsubsti |
| 4810715 |
Imidazoyl-substituted thiomethylpyridine derivatives, method of administration thereof and medic |
March 7, 1989 |
| Thiomethylpyridine derivatives having bronchosecretolytic and mucolytic activity according to the formula: ##STR1## wherein R is a group attached in the 2-, 3- or 4-position of the pyridine ring which corresponds to the following general formula: wherein Q is a substituted or unsubst |
| 4738960 |
1,3,4-Thiadiazole derivatives and pharmaceutical preparations useful as inhibitors for histamine |
April 19, 1988 |
| 1,3,4-Thiadiazole derivatives corresponding to the general formula I ##STR1## which constitute highly effective inhibitors for histamine-H.sub.2 receptors are described. These compounds in addition have a cytoprotective action. |
| 4732986 |
Benzothiazole derivatives, processes for their preparation and pharmaceutical compositions conta |
March 22, 1988 |
| Benzothiazole derivatives corresponding to the general formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent, independently of one another, a hydrogen atom, a halogen atom, a linear C.sub.1 -C.sub.3 -alkyl group or a linear C.sub.1 -C.sub.3 -alkoxy group, R.sup.5 |
| 4727081 |
3,4-Diazole derivatives and pharmaceutical preparations containing these compounds |
February 23, 1988 |
| 3,4-Diazole derivatives corresponding to the general formula I ##STR1## which exert a highly selective action on histamine-H.sub.2 receptors are described. Processes for the preparation of these compounds and pharmaceutical preparations containing these compounds are also described. |
| 4666921 |
Pyrazole derivatives, processes for their preparation and pharmaceutical preparations containing |
May 19, 1987 |
| Special pyrazole derivatives corresponding to the general formula I which have a highly selective action on histamine-H.sub.2 receptors are described. Compared with other drugs known to be effective in their action on histamine-H.sub.2 receptors, these compounds have improved pharmac |
| 4659721 |
Alkanol derivatives, and pharmaceutical preparation containing these compounds |
April 21, 1987 |
| Alkanol derivatives corresponding to the general formula Iwhich have a highly selective action on histamine-H.sub.2 receptors are described. Due to this action, these compounds may advantageously be used for treatment of diseases caused by raised gastric secretion. |
| 4656180 |
Diamine derivatives and pharmaceutical preparations containing these compounds |
April 7, 1987 |
| Diamine derivatives corresponding to the general formula Iwhich have a highly selective action on histamine-H.sub.2 receptors and are therefore suitable for use as anti-ulcerative agents are described. Processes for the preparation of these compounds and pharmaceutical preparations conta |
| 4600721 |
Pharmaceutical preparation |
July 15, 1986 |
| Pharmaceutical preparations having an antiphlogistic action are described. The preparations contain, as active ingredient, a benzazole derivative corresponding to the general tautomeric formulae I ##STR1## wherein X represents a sulphur or oxygen atom and R.sup.1 represents a hyd |
| 4599346 |
Propan-2-ol derivatives, a process for their production and medicaments containing these compoun |
July 8, 1986 |
| The invention relates to new propan-2-ol derivatives corresponding to the following general formula ##STR1## in which R represents ##STR2## and to salts thereof with pharmacologically acceptable acids. These compounds have a selective effect on histamine-H.sub.2 -receptors. |
| 4596811 |
Heterocyclic compounds, a process for their production and medicaments containing these compound |
June 24, 1986 |
| The invention relates to special heterocyclic compounds corresponding to general tautomeric formula I which are distinguished by improved antagonistic activity on histamine-H.sub.2 -receptors. The invention also relates to a process for producing these compounds and to medicaments co |
| 4559344 |
Pyridine-pyrimidinone derivatives, a process for their production and H.sub. -antagonist medicam |
December 17, 1985 |
| The invention relates to new pyridine-pyrimidinone derivatives corresponding to the following general formula ##STR1## wherein R.sup.1 represents linear C.sub.1-6 alkyl or cycloalkyl and R.sup.2 represents linear C.sub.1-6 alkyl or R.sup.1 and R.sup.2 together with the nitrogen a |
