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Inventor:
Suzawa; Toshiyuki
Address:
Yamato, JP
No. of patents:
9
Patents:












Patent Number Title Of Patent Date Issued
7547675 Chemically modified polypeptides June 16, 2009
The present invention relates to a chemically modified polypeptide in which at least one of hydroxyl groups in the polypeptide molecule is modified with a polyalkylene glycol derivative; a method for producing the modified polypeptide; a method of treatment using the modified polypep
7291713 Branched polyalkylene glycols November 6, 2007
The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group convertible into
6642355 Endothelin-antagonizing peptide November 4, 2003
The invention relates to an endothelin antagonistic peptide of the formula (I):wherein represents Asn or Asp; B represents His or Lys; E represents Ala or Ser; G represents Ala or Pro; X represents X.sup.1 -Gly or ##STR1## and Y represents hydroxy, lower alkoxy, amino, #
6638509 Toxin conjugates October 28, 2003
The present invention relates to a toxin conjugate in which a residue derived from a compound having an affinity for a target cell is bound to a toxin through a spacer comprising polyalkylene glycol and dipeptide.
6583267 Chemically modified polypeptides June 24, 2003
The present invention relates to a chemically modified polypeptide in which at least one of hydroxyl groups in the polypeptide molecule is modified with a polyalkylene glycol derivative; a method for producing the modified polypeptide; a method of treatment using the modified polypeptide
6194195 Strains of streptomyces producing endothelin antagonistic peptides February 27, 2001
The invention relates to biologically pure cultures of Streptomyces sp. RE-701 (FERM BP-3624) and Streptomyces sp. RE-629 (FERM BP-4126) that produce endothelin antagonistic peptides.
6103236 Toxin conjugates August 15, 2000
The present invention relates to a toxin conjugate in which a residue derived from a compound having an affinity for a target cell is bound to a toxin through a spacer comprising polyalkylene glycol and dipeptide.
5639860 Endothelin-antagonizing peptide June 17, 1997
Peptides represented by the following formula (I): ##STR1## wherein A represents Asn or Asp; B represents His or Lys; and E represents Ala or Ser;(1) X.sup.1 and Y.sup.1 are combined together to form a single bond as X.sup.1 --Y1, or (2) X.sup.1 represents hydrogen and Y.sup.1 repres
5631222 Endothelin-antagonizing peptide May 20, 1997
Disclosed is a peptide compound represented by the following formula (I):wherein R.sup.1-12, R.sup.14-18, and R.sup.20 are as defined in the specification.










 
 
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