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Inventor:
Stapleton; Marilyn J.
Address:
Durham, NC
No. of patents:
8
Patents:












Patent Number Title Of Patent Date Issued
RE35716 Temperature control apparatus and method January 20, 1998
An apparatus and method for performing automated sample preparation, DNA amplification and detection, which apparatus has heat-sinking, flat carriers for holding specimens and reagents, devices for heating and cooling and maintaining the specimen to or at any given temperature for an
6103192 Immobilizing and processing specimens on matrix materials for the identification of nucleic acid August 15, 2000
The invention is a method and device for collecting and processing a biological specimen for the analyses of nucleic acids. A device comprises a matrix to which cells and viruses adhere and a handle to manipulate the matrix. The devices are used to collect, dry, transport, store and proc
5451500 Device for processing biological specimens for analysis of nucleic acids September 19, 1995
A system is provided for the automated detection of target nucleic acid sequences in which multiple biological samples are individually incorporated into matrices within carriers in a two-dimensional format. The matrix carrier is an inexpensive, disposable unit that represents a clos
5436129 Process for specimen handling for analysis of nucleic acids July 25, 1995
A process for handling a biological specimen for the analysis of nucleic acid sequences wherein the biological specimen is immobilized within a carrier device for controlled temperature conditions and the sequential addition of fluid treatments. The fluid treatments arm selected from
5382511 Method for studying nucleic acids within immobilized specimens January 17, 1995
An apparatus for the automated detection of target nucleic acid sequences in which multiple biological samples are individually incorporated into a matrix and treated in a stepwise fashion to expose, amplify, detect and enumerate the presence of original, target nucleotide sequences in e
5346672 Devices for containing biological specimens for thermal processing September 13, 1994
A cover has been designed to make a sealed chamber over a desired specimen area to control reagent evaporation which is critical for amplifying DNA in slide specimens. The cover is positioned over the specimen and temporarily adhered to, or pushed against, the slide, forming a sealed
5281516 Temperature control apparatus and method January 25, 1994
An apparatus and method for performing automated sample preparation, DNA amplification and detection, which apparatus has heat-sinking, flat carriers for holding specimens and reagents, devices for heating and cooling and maintaining the specimen to or at any given temperature for an
5188963 Device for processing biological specimens for analysis of nucleic acids February 23, 1993
The matrix carrier is a hinged compartment facilitating automation of DNA- and RNA-based diagnostics and genetic surveillance and detection. Specimens are embedded in a matrix in the carrier. The matrix is then treated by one or more of the techniques such as amplification, electroph










 
 
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