Resources Contact Us Home Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE     Inventor: Spruce; Lyle W. Address: Arvada, CO No. of patents: 14 Patents: Patent Number Title Of Patent Date Issued 6159938 Serine protease inhibitors comprising .alpha.-keto heterocycles December 12, 2000 Provided are methods of inhibiting the activity of a serine protease using protease inhibitors that include an alpha-keto heterocycle in their structure. The methods are useful in the treatment of ischemic heart or treatment of symptoms associated with blood coagulation disorders. Also 6075120 Bradykinin antagonist June 13, 2000 A bradykinin antagonist of the formula:where BKAn is a bradykinin antagonist peptide; Y is a pharmacore; and X is a bridging link chemically joining the BKAn and Y components. 6037325 Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil e March 14, 2000 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases including human neutrophil elastase, equivalently known as human leukocyte elastase. 5891852 Serine protease inhibitors-cycloheptane derivatives April 6, 1999 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respiratory distress syndrome, septi 5874585 Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil e February 23, 1999 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases including human neutrophil elastase, equivalently known as human leukocyte elastase. 5869455 Serine protease inhibitors-N-substituted derivatives February 9, 1999 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respiratory distress syndrome, septi 5863899 Bradykinin antagonists January 26, 1999 A bradykinin antagonist of the formula:where BKAn is a bradykinin antagonist peptide; Y is a Pharmacophore; and X is a bridging link chemically joining the BKAn and Y components. 5861380 Serine protease inhibitors-keto and di-keto containing ring systems January 19, 1999 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respiratory distress syndrome, septi 5843900 Bradykinin antagonists December 1, 1998 The present invention relates to pharmaceutically effective heterodimers comprising a bradykinin antagonist component covalently linked to a mu-opioid agonist component. 5807829 Serine protease inhibitor--tripeptoid analogs September 15, 1998 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respiratory distress syndrome, septi 5801148 Serine protease inhibitors-proline analogs September 1, 1998 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respiratory distress syndrome, septi 5663416 Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase September 2, 1997 2-Phenylalkanoate esters which are useful as inhibitors of human leukocyte elastase. 5618792 Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil e April 8, 1997 The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases including human neutrophil elastase, equivalently known as human leukocyte elastase. 5214191 Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase May 25, 1993 2-Phenylalkanoate esters which are useful as inhibitors of human leukocyte elastase.       Recently Added Patents Method and assembly for determining the temperature of a test sensor Computer system and volume migration control method using the same Baseball player stationery tab Method and system for testing indirect bandgap semiconductor devices using luminescence imaging Unsupervised document clustering using latent semantic density analysis (4931 Food-grade flour from dry fractionated corn germ and collet composition and method for producing same   Randomly Featured Patents Vehicle headlight Gas display panel with internal heater Apparatus for programmably converting an operating voltage of a CPU and chipset Bulk enhancing forming fabrics Treating oxidized steels in low-sulfur reforming processes Antiviral therapy for hepatitis B with 2',3'-dideoxypurine nucleosides Continuously variable transmission control apparatus Process of paraffin isomerization and heteropoly acids supported on inert supports as isomerization catalysts Taxoids, their preparation and pharmaceutical compositions containing them Materials, methods, and kits for reducing nonspecific binding of molecules to a surface © 2006-2011. 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