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Inventor:
Smith; Emilie Despagnet
Address:
Raleigh, NC
No. of patents:
7
Patents:




Patent Number Title Of Patent Date Issued
7553968 Synthesis of nicotine derivatives from nicotine June 30, 2009
Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described.
7501520 Regioselective halogenation of nicotine and substituted nicotines March 10, 2009
A first aspect of the present invention is a method for of making a compound of Formula Ia or Formula Ib: ##STR00001## wherein X is halo, by (a) metalating a precursor compound to form an organometallic intermediate, and then reacting the organometallic intermediate with a halogenat
7361768 Synthesis of nicotine derivatives from nicotine April 22, 2008
Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described.
7179917 Regioselective halogenation of nicotine and substituted nicotines February 20, 2007
A first aspect of the present invention is a method for of making a compound of Formula Ia or Formula Ib: ##STR00001## wherein X is halo, by (a) metalating a precursor compound to form an organometallic intermediate, and then reacting the organometallic intermediate with a halogenat
7132545 Synthesis of nicotine derivatives from nicotine November 7, 2006
Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described.
7067672 Regioselective halogenation of nicotine and substituted nicotines June 27, 2006
A first aspect of the present invention is a method for of making a compound of Formula Ia or Formula Ib: ##STR00001## wherein X is halo, by (a) metalating a precursor compound to form an organometallic intermediate, and then reacting the organometallic intermediate with a halogenat
6995265 Synthesis of nicotine derivatives from nicotine February 7, 2006
Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described.


 
 
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