| Patent Number |
Title Of Patent |
Date Issued |
| 7553968 |
Synthesis of nicotine derivatives from nicotine |
June 30, 2009 |
| Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described. |
| 7501520 |
Regioselective halogenation of nicotine and substituted nicotines |
March 10, 2009 |
| A first aspect of the present invention is a method for of making a compound of Formula Ia or Formula Ib: ##STR00001## wherein X is halo, by (a) metalating a precursor compound to form an organometallic intermediate, and then reacting the organometallic intermediate with a halogenat |
| 7361768 |
Synthesis of nicotine derivatives from nicotine |
April 22, 2008 |
| Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described. |
| 7179917 |
Regioselective halogenation of nicotine and substituted nicotines |
February 20, 2007 |
| A first aspect of the present invention is a method for of making a compound of Formula Ia or Formula Ib: ##STR00001## wherein X is halo, by (a) metalating a precursor compound to form an organometallic intermediate, and then reacting the organometallic intermediate with a halogenat |
| 7132545 |
Synthesis of nicotine derivatives from nicotine |
November 7, 2006 |
| Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described. |
| 7067672 |
Regioselective halogenation of nicotine and substituted nicotines |
June 27, 2006 |
| A first aspect of the present invention is a method for of making a compound of Formula Ia or Formula Ib: ##STR00001## wherein X is halo, by (a) metalating a precursor compound to form an organometallic intermediate, and then reacting the organometallic intermediate with a halogenat |
| 6995265 |
Synthesis of nicotine derivatives from nicotine |
February 7, 2006 |
| Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described. |