| Patent Number |
Title Of Patent |
Date Issued |
| 5643464 |
Process for preparing a sterile, dry crosslinking agent |
July 1, 1997 |
| The present invention discloses a novel method for preparing crosslinked biomaterial compositions for use in the augmentation of soft or hard tissue. In general, the method comprises mixing a biocompatible polymer, which is preferably collagen, with a sterile, dry crosslinking agent, |
| 5550187 |
Method of preparing crosslinked biomaterial compositions for use in tissue augmentation |
August 27, 1996 |
| The present invention discloses a novel method for preparing crosslinked biomaterial compositions for use in the augmentation of soft or hard tissue. In general, the method comprises mixing a biocompatible polymer, which is preferably collagen, with a sterile, dry crosslinking agent, |
| 5527856 |
Method of preparing crosslinked biomaterial compositions for use in tissue augmentation |
June 18, 1996 |
| The present invention discloses a novel method for preparing crosslinked biomaterial compositions for use in the augmentation of soft or hard tissue. In general, the method comprises mixing a biocompatible polymer, which is preferably collagen, with a sterile, dry crosslinking agent, |
| 5425770 |
Calcium phosphate/atelopeptide collagen compositions for bone repair |
June 20, 1995 |
| Processes for the preparation of compositions used in conductive bone repair are disclosed. The compositions contain a mixture consisting essentially of either a calcium phosphate particulate mineral component or particulate hydroxyapatite in admixture with atelopeptide reconstituted |
| 5383930 |
Method for treating fine superficial facial lines |
January 24, 1995 |
| A device for correcting fine superficial facial lines which comprises a syringe fitted with a 31-33 gauge needle and an aqueous suspension of noncrosslinked fibrillar atelopeptide collagen contained within the syringe barrel, the concentration of collagen in the suspension being in t |
| 5366498 |
Device for treating fine superficial facial lines |
November 22, 1994 |
| A device for correcting fine superficial facial lines which comprises a syringe fitted with a 31-33 gauge needle and an aqueous suspension of noncrosslinked fibrillar atelopeptide collagen contained within the syringe barrel, the concentration of collagen in the suspension being in t |
| 5246457 |
Xenogeneic collagen/mineral preparations in bone repair |
September 21, 1993 |
| A composition for use in bone repair, in particular, in only procedures, which comprises calcium phosphate mineral particles in admixture with atelopeptide reconstituted fibrillar collagen preparations is disclosed. This composition is non-immunogenic and encourages the fusion of host bo |
| 5123925 |
Gamma irradiation of collagen/mineral mixtures |
June 23, 1992 |
| The present invention is a method for treating bony defects. The method involves contacting the bony defect with a formable composition and allowing the formable composition to solidify. The formable composition is comprised of 2-40% of reconstituted fibrillar atelopeptide collagen and |
| 5035715 |
Gamma irradiation of collagen/mineral mixtures |
July 30, 1991 |
| A biocompatible collagen/mineral composition which comprises a mixture of 2-40% reconstituted fibrillar atelopeptide collagen and 60-98% calcium phosphate mineral by weight, exclusive of water, is disclosed. The composition has a sterility assurance factor of at least as low as 10.su |
| 4992226 |
Method of making molds with xenogeneic collagen/mineral preparations for bone repair |
February 12, 1991 |
| A process for coating the pores of a mineral matrix with collagen by pumping collagen through the molded matrix is disclosed. The resulting coated matrix can be used as a prosthesis in bone repair. |
| 4865602 |
Gamma irradiation of collagen/mineral mixtures |
September 12, 1989 |
| A process for sterilization of collagen/mineral compositions using .gamma. radiation is conducted under conditions which produce a product of desired handling and biocompatibility properties. |
| 4795467 |
Xenogeneic collagen/mineral preparations in bone repair |
January 3, 1989 |
| A composition for use in bone repair, in particular, in onlay procedures, which comprises calcium phosphate mineral particles in admixture with atelopeptide reconstituted fibrillar collagen preparations is disclosed. This composition is non-immunogenic and encourages the fusion of host b |
| 4789663 |
Methods of bone repair using collagen |
December 6, 1988 |
| A method of repairing bone defects by use of suspensions containing purified atelopeptide, reconstituted, fibrillar skin collagen or bone collagen powder or mixtures thereof is disclosed. The suspensions provide matrices for conductive growth of bone into the defect. The skin collagen |
| 4582640 |
Injectable cross-linked collagen implant material |
April 15, 1986 |
| Cross-linked atelopeptide collagen that is substantially free of residual cross-linking agent is prepared by: reconstituting atelopeptide collagen from solution by neutralizing the solution at a reduced temperature and a hypotonic ionic strength; cross-linking the reconstituted fibers in |