| Patent Number |
Title Of Patent |
Date Issued |
| RE34091 |
Sialic acid derivatives having active carbonyl group |
October 6, 1992 |
| A sialic acid derivative having an active carbonyl group represented by the formula [I]: ##STR1## wherein R.sup.1 represents hydrogen or acetyl group; R.sup.2 represents hydrogen, a metal or a lower alkyl group; R.sup.3 represents hydrogen, hydroxyl gorup, or a residue removed hy |
| 5158886 |
Monoclonal antibodies specific for free N-acetylfuraminic acid and beta-glycosides and beta-glyc |
October 27, 1992 |
| A hybridoma producing a monoclonal antibody specific for free N-acetylneuraminic acid or beta glycoconjugates thereof, is herein disclosed. The hybridoma can be generated by fusing (i) B cells of lymphocytes obtained by immunizing an animal with an N-acetylneuraminic acid or a beta-g |
| 5141864 |
Monoclonal antibody recognizing alpha 2.fwdarw.3 bonds |
August 25, 1992 |
| A hybridoma capable of producing a monoclonal antibody specific to a sialic acid containing glycolipid carrying N-acetylneuraminic acid residue having alpha 2.fwdarw.3 linkage is herein disclosed. The hybridoma can be generated by fusing (i) B cells or lymphocytes obtained by immunizing |
| 5126330 |
Sialosyl cholesterol and neuropathy remedy comprising the same |
June 30, 1992 |
| The present invention relates to a sodium salt of sialosyl cholesterol. The present compound has an excellent high water solubility, and therefore the compound is very useful as a medicine to be used for treating various diseases derived from lesions of peripheral or central nerves. |
| 5101026 |
Ganglioside related compounds and method of producing the same |
March 31, 1992 |
| The present invention relates to ganglioside related compounds having, for example, the following formula: ##STR1## where R.sub.1 represents H or COCH.sub.3 (hereinafter abbreviated to "AC"); R.sub.2 represents H or CH.sub.3 ; and R.sub.3 represents --OH, ##STR2## These gangl |
| 5057605 |
Sialocylglycerolipids and method for preparing the same |
October 15, 1991 |
| Sialocylglycerolipids represented by the following general formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom or a group CH.sub.3 CO--; R.sup.2 represents an alkali metal, a hydrogen atom or a lower alkyl group; R.sup.3 represents a hydrogen atom or a group C.sub.n H.su |
| 5023239 |
Sialosyl cholesterol, process for producing the same, and neuropathy remedy comprising the same |
June 11, 1991 |
| The present invention relates to a sodium salt of sialosyl cholesterol. The present compound has an excellent high water solubility, and therefore the compound is very useful as a medicine to be used for curing various diseases derived from lesions of peripheral or central nerves. |
| 5015631 |
Repairing agent for cells and tissues |
May 14, 1991 |
| A repairing agent for cells and tissues is disclosed, which agent comprises, as an active ingredient, a compound of the general formula: ##STR1## wherein Z represents lithium, potassium, sodium, ammonium or an organic ammonium when n is 1, and Z represents calcium, barium or magnesiu |
| 4990604 |
Asialoganglioside related compounds |
February 5, 1991 |
| Method for the production of asialoganglioside related compounds of the formula (I). ##STR1## wherein R.sup.1 is hydrogen or benzoyl, R.sup.2 is hydrogen or acetyl, R.sup.3 is hydrogen, acetyl, .beta.-D-galactopyranosyl or 2,3,4,6-tetra-O-acetyl-.beta.-D-galactopyranosyl, R.sup.7 |
| 4990603 |
Sialic acid derivatives and process therefor |
February 5, 1991 |
| The present invention relates to sialic acid derivatives. According to the present invention, there is provided sialic acid derivatives having the general formula (I): ##STR1## wherein, R.sup.1 represents hydrogen, an acetyl group, a trityl group, ##STR2## (R.sup.5 represents |
| 4968786 |
Sialic acid derivatives, galactose derivatives and method for producing the same |
November 6, 1990 |
| Novel sialic acid derivatives and galactose derivatives which are useful intermediate for the synthesis of gangliosides. Methods for the production of the sialic acid and galactose derivatives. Methods for the production of ganglioside GM.sub.3. |
| 4950750 |
Glycolipid containing N-glycolylneuraminic acid and method of producing the same |
August 21, 1990 |
| The present invention provides ganglioside-related compounds expressed by the following formula: ##STR1## (wherein R.sub.1 denotes a hydrogen atom or SiR.sub.3 R.sub.4 R.sub.5 (wherein R.sub.3 and R.sub.4 each denotes a methyl or phenyl group, and R.sub.5 denotes a tertiary butyl |
| 4918177 |
Sialic acid derivatives having active carbonyl group |
April 17, 1990 |
| A sialic acid derivative having an active carbonyl group represented by the formula [I]: ##STR1## wherein R.sup.1 represents hydrogen or acetyl group; R.sup.2 represents hydrogen, a metal or a lower alkyl group; R.sup.3 represents hydrogen, hydroxyl group, or a residue removed hy |
| 4880572 |
Un-natural ceramide related compounds and preparation thereof |
November 14, 1989 |
| Novel unnatural ceramide related compounds, for instance, (2S, 3S)-2-tetracosanamido-octadecane-1,3-diol are herein provided, which are useful as intermediates in preparing ceramide moieties employed in the preparation of glycolipids and gangliosides known as tumor markers or molecul |
| 4797477 |
Process for preparing sialic acid derivatives |
January 10, 1989 |
| The present invention relates to a new process for preparing 3-O-(sodium(5-acetamide-3,5-dideoxy-alpha-D-glycero-D-galacto-2-noneuro pyranosyl)onate-1,2-di-O-tetradecyl-Sn-glycerol (3) consisting essentially of hydrolyzing a 3-O-(C.sub.1-5 alkyl(5-acetamide-4,7,8,9-tetra-O-acetyl-3,5 |
| 4788200 |
Method and composition for treating arteriosclerosis |
November 29, 1988 |
| A medicament for curing arteriosclerosis which comprises pyrimido [2,1-b] benzothiazole derivative. |
| 4774327 |
N-glycolylneuraminic acid derivative |
September 27, 1988 |
| This invention provides a novel compound having the following formula: ##STR1## This compound is a useful intermediate for the preparation of N-glycolylneuraminic acid: ##STR2## |
| 4774326 |
Process for preparing N-glycolylneuraminic acid derivatives |
September 27, 1988 |
| This invention provides a novel process for preparing a compound represented by the formula ##STR1## In accordance with this invention, the compound is prepared by reacting a compound represented by the formula ##STR2## with glycolic acid in the presence of dicyclohexylcarbod |
| 4751290 |
Sialosylcerebrosides |
June 14, 1988 |
| This invention provides a novel compound having a formula such as ##STR1## This invention also provides a process for preparing such a compound. |
| 4730058 |
Sialosylceramides and production method thereof |
March 8, 1988 |
| This invention provides a novel compound expressed by the following formula (1): ##STR1## [wherein R.sup.1 denotes a hydrogen atom or CH.sub.3 CO--, R.sup.2 denotes --COOR.sup.4 (R.sup.4 denotes Na or a methyl group) or ##STR2## (R.sup.5 denotes a hydrogen atom, --COC.sub.6 H |
| 4698332 |
Expectorant |
October 6, 1987 |
| An expectorant capable of acting on the rheological properties of sputum and capable of directly promoting the ciliary motion. The expectorant contains N-acetylneuraminic acid or a pharmaceutically active salt thereof. |
| 4675391 |
Glycoside derivatives |
June 23, 1987 |
| This invention provides a novel compound having a formula such as ##STR1## This invention also provides a process for preparing such a compound. The novel compound has excellent immunological activity. |
| 4663443 |
N-substituted neuraminic acid derivatives |
May 5, 1987 |
| This invention provides a novel compound having a formula such as ##STR1## This invention also provides a process for preparing such a compound. The novel compound has an excellent immunological activity. |
