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Inventor:
Shinkawa; Toyohide
Address:
Machida, JP
No. of patents:
20
Patents:












Patent Number Title Of Patent Date Issued
8158760 Glycoengineered, recombinant antibody April 17, 2012
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
8067232 Antibody composition-producing cell with inactivated A-1,6-fusocyltransferase November 29, 2011
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
8039595 Glycoengineered, recombinant antibody to CCR-4 with reduced fucosylation October 18, 2011
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
7846725 Antibody composition-producing cell in which enzyme expression is inhibited by RNAi December 7, 2010
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
7763246 Method of modulating the activity of functional immune molecules to platelet-derived growth fact July 27, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7741442 Antibody composition exhibiting increased cellular cytotoxicity due to glycosylation June 22, 2010
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
7737325 Antibody composition-producing cell June 15, 2010
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-modulated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
7718175 Method of modulating the activity of functional immune molecules to interleukin-5 receptor prote May 18, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7708997 Method of modulating the activity of functional immune molecules May 4, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7708992 Methods for producing antibody compositions with increased ADCC May 4, 2010
The invention relates to methods for modulating the antibody-dependent cellular cytotoxicity of an IgG antibody composition.
7687061 Method of modulating the activity of functional immune molecules to Her-2 March 30, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7682611 Method of modulating the activity of functional immune molecules to CXCR4 protein March 23, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7682610 Method of modulating the activity of functional immune molecules March 23, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7655228 Method of modulating the activity of functional immune molecules to GM2 February 2, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7651688 Method of modulating the activity of functional immune molecules to CD52 January 26, 2010
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule ha
7425446 Antibody composition-producing cell September 16, 2008
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
7393683 Mammalian host cell modified by RNAi to inhibit .alpha. 1,6-fucosyltransferase July 1, 2008
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the
7214775 Method of modulating the activity of functional immune molecules May 8, 2007
The invention relates to a method for controlling the activity of an immunologically functional molecules, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule h
7064191 Process for purifying antibody June 20, 2006
The present invention relates to a process for purifying an antibody having a desired property, which comprises using a substance having an affinity to a carbohydrate binding to the antibody; a medicament comprising, as an active ingredient, the antibody purified by the process; and
6946292 Cells producing antibody compositions with increased antibody dependent cytotoxic activity September 20, 2005
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the










 
 
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