| Patent Number |
Title Of Patent |
Date Issued |
| 7381746 |
2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivative |
June 3, 2008 |
| One object of the present invention is to provide a drug that is effective in treatments for and prevention of psychiatric disorders and in treatments for and prevention of neurological diseases, inhibiting a Group II metabotropic glutamate receptor.The object is solved by a 2-amino- |
| 7157594 |
6-Fluorobicyclo[3.1.0]hexane derivatives |
January 2, 2007 |
| An antidepressant comprising, as an active ingredient, a compound having an antagonistic effect on group II metabotropic glutamate receptors, as well as a 2-amino-3-alkoxy-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivative of Formula [I]: ##STR00001## [wherein R.sup.1 and |
| 6770676 |
Dicarboxylic acid derivatives |
August 3, 2004 |
| The present invention relates to 2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives represented by the formula: ##STR1##the pharmaceutically acceptable salts thereof, or the hydrates thereof. The compounds of the present invention are useful as a medicament, and i |
| 6500958 |
Carboxylic acid derivatives and process for producing the same |
December 31, 2002 |
| The present invention relates to compounds which are useful for efficient synthesis of 2-amino-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acids.The compounds according to the present invention comprise 2-oxobicyclo[3.1.0]hexane-6-carboxylic acid derivatives represented by the formula as |
| 6479674 |
Carboxylic acid derivatives and process for producing same |
November 12, 2002 |
| The present invention relates to compounds which are useful for efficient synthesis of 2-amino-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acids.The compounds according to the present invention comprise 2-oxobicyclo[3.1.0]hexane-6-carboxylic acid derivatives represented by the formula as |
| 6392086 |
Intermediates and process for producing fluorine-containing amino acid compound by using the sam |
May 21, 2002 |
| The present inventions relate to a (1S,5R,6S)- or (1SR, 5RS, 6SR)-3-fluoro-2-oxobicyclo[3.1.0]hex-3-ene-6-carboxylic acid derivative represented by Formula (1): ##STR1##[in the formula, R represents OR.sup.1 or NR.sup.1 R.sup.2, wherein R.sup.1 and R.sup.2 are identical or different, |
| 6333428 |
6-fluorobicyclo[3.1.0]hexane derivatives |
December 25, 2001 |
| The present invention provides fluorobicyclo[3.1.0]hexane derivatives represented by the formula ##STR1##[wherein R.sup.1 and R.sup.2 are the same or different and each represents a hydrogen atom, a C.sub.1-10 alkyl group, a C.sub.3-8 cycloalkyl group or a C.sub.3-8 cycloalkyl-C.sub. |
| 6316498 |
Fluorine-containing amino acid derivatives |
November 13, 2001 |
| Fluorine-containing amino acid derivatives represented general formula (I), pharmaceutically acceptable salts thereof or hydrates of the same, wherein X.sup.1 represents hydrogen or fluorine; and R.sup.1 and R.sup.2 are the same or different and each represents hydrogen or lower C.sub.1- |
