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Inventor:
Ruhter; Gerd
Address:
Hamburg, DE
No. of patents:
13
Patents:




Patent Number Title Of Patent Date Issued
6756403 Methods for producing chiral chromones, chromanes, amino substituted chromanes and intermediates June 29, 2004
Disclosed are process steps and novel processes for producing chromane compositions enriched in at least one (2R or 2S) enantiomer, preferably chroman-2-yl carboxylic acid compounds and chroman-2-yl carboxylic acid esters which are intermediates for producing platelet aggregation inh
6693109 Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation February 17, 2004
This invention relates to certain spirocyclic compounds substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.
6528534 Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation March 4, 2003
This invention relates to certain spirocyclic compounds substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.
6448269 Glycoprotein IIb/IIIa antagonists September 10, 2002
This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, benzopyran, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are
6410562 Hypoglycemic imidazoline compounds June 25, 2002
This invention relates to certain novel imidazoline compounds and analogues thereof, to their use for the treatment of diabetes, diabetic complications, metabolic disorders, or related diseases where impaired glucose disposal is present, to pharmaceutical compositions comprising them
6291469 Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation September 18, 2001
This invention relates to certain spirocyclic compounds substituted with both basic and acidic functionality, as shown by formula (I): ##STR1##wherein Q, L, A.sub.i, B.sub.j, R.sub.0, R.sub.3, R.sub.10, m, n, p and q are as defined in the disclosure, which are useful in inhibiting of
6020362 Glycoprotein IIB IIIA antagonists February 1, 2000
This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, benzopyran, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are
5731324 Glycoprotein IIb/IIIa antagonists March 24, 1998
This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, benzopyran, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are
5668152 Protein kinase C inhibitors September 16, 1997
The present invention discloses compounds that are highly isozyme selective protein kinase C beta-1 and beta-2 isozyme inhibitors. Accordingly, the present invention provides a method of selectively inhibiting protein kinase C isozymes beta-1, and beta-2. As isozyme selective inhibitors
5602137 Pyrimidine compounds and their use as pharmaceuticals February 11, 1997
Compounds for treating cardiovascular or circulatory disorders of the formula ##STR1## and pharmaceutically acceptable salts thereof wherein R.sup.1, R.sup.2, R.sup.3, R.sup.7, Ar.sup.1, Ar.sup.2, X, Y, and n are defined herein.
5602136 Pyrimidine compounds and their use as pharmaceuticals February 11, 1997
Compounds having the formula ##STR1## and the other variables are as defined herein, and are indicated for use in the treatment and prophylaxis of, for example, hypertension, congestive heart failure, ocular hypertension, renal failure, and CNS disorders, or are intermediates the
5571813 Fused pyrimidine compounds and their use as pharmaceuticals November 5, 1996
Pharmaceutical compounds which are azolo-fused pyrimidine compounds having the formula ##STR1## in which .dbd.A--B-- together with the pyrimidine ring forms a) a pyrazolo[1,5-a]pyrimidine of formula (A), ##STR2## b) a [1,2,4]triazolo[1,5-a]pyrimidine of formula (B), ##STR
5545636 Protein kinase C inhibitors August 13, 1996
The present invention discloses compounds of the general formula: ##STR1## The compounds are highly isozyme selective protein kinase C beta-1 and beta-2 isozyme inhibitors. Accordingly, the present invention provides a method of selectively inhibiting protein kinase C isozymes beta-1


 
 
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