Patent Number |
Title Of Patent |
Date Issued |
6368803 |
Detection of nucleic acids by target-catalyzed formation |
April 9, 2002 |
A method is disclosed for modifying an oligonucleotide, which method has application to the detection of a polynucleotide analyte. An oligonucleotide is reversibly hybridized with a polynucleotide, for example, a polynucleotide analyte, in the presence of a 5'-nuclease under isotherm |
6121001 |
Detection of nucleic acids by target-catalyzed product formation |
September 19, 2000 |
A method is disclosed for modifying an oligonucleotide, which method has application to the detection of a polynucleotide analyte. An oligonucleotide is reversibly hybridized with a polynucleotide, for example, a polynucleotide analyte, in the presence of a 5'-nuclease under isotherm |
6110677 |
Oligonucleotide modification, signal amplification, and nucleic acid detection by target-catalyz |
August 29, 2000 |
A method is disclosed for modifying an oligonucleotide, which method has application to the detection of a polynucleotide analyte. An oligonucleotide is reversibly hybridized with a polynucleotide, for example, a polynucleotide analyte, in the presence of a 5'-nuclease under isotherm |
5914230 |
Homogeneous amplification and detection of nucleic acids |
June 22, 1999 |
The present invention relates to a method for detecting or amplifying and detecting a target polynucleotide sequence. The method comprises providing in combination (i) a medium suspected of containing the target polynucleotide sequence, (ii) all reagents required for conducting an am |
5882867 |
Detection of nucleic acids by formation of template-dependent product |
March 16, 1999 |
A method is disclosed for detecting a target polynucleotide sequence. The method comprises incubating an oligonucleotide with the target polynucleotide sequence and a nucleotide polymerase under isothermal conditions wherein at least one nucleotide is added to the 3'-terminus of the |
5882857 |
Internal positive controls for nucleic acid amplification |
March 16, 1999 |
The present invention relates to an improvement in a method for amplifying a target sequence of a target polynucleotide. The method comprises combining a sample suspected of containing the target polynucleotide with reagents for amplifying the target sequence and subjecting the combinati |
5792614 |
Detection of nucleic acids by target-catalyzed product formation |
August 11, 1998 |
A method is disclosed for modifying an oligonucleotide, which method has application to the detection of a polynucleotide analyte. An oligonucleotide is reversibly hybridized with a polynucleotide, for example, a polynucleotide analyte, in the presence of a 5'-nuclease under isotherm |
5605796 |
Method for preventing amplification of nucleic acid contaminants in amplification mixtures using |
February 25, 1997 |
Methods and kits are disclosed for preventing amplification of contaminating copies of nucleic acids during in amplification of a nucleic acid suspected of being present in a sample. Modified nucleotides that render copies of the nucleic acid bindable by a member of a specific bindin |