| Patent Number |
Title Of Patent |
Date Issued |
| 7468359 |
Compositions comprising oxophosphonate-based metalloproteinase inhibitors |
December 23, 2008 |
| The present invention relates to compositions useful for treating or controlling disease states or conditions associated with zinc containing proteinases, especially metalloproteinases. The active ingredient in these compositions is an alpha-oxo- or alpha-thioxophosphonate of formula |
| 7345033 |
Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them |
March 18, 2008 |
| The present invention provides a compound of the following formula I: R.sup.3--NH--C(.dbd.X)--P(.dbd.O)OR.sup.1OR.sup.2 including pharmaceutically acceptable salts, solvates, hydrates and polymorphs of the compounds of formula I, as well as geometrical isomers and optically active f |
| 7101864 |
Compositions comprising oxophosphonate-based metalloproteinase inhibitors |
September 5, 2006 |
| The present invention relates to compositions useful for treating or controlling disease states or conditions associated with zinc containing proteinases, especially metalloproteinases. The active ingredient in these compositions is an alpha-oxo- or alpha-thixophosphpnate of formula |
| 7034006 |
Use of lipid conjugates in the treatment of disease |
April 25, 2006 |
| The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE |
