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Inventor:
Raschack; Manfred
Address:
Weisenheim, DE
No. of patents:
22
Patents:




Patent Number Title Of Patent Date Issued
7601730 Carboxylic acid derivatives, their preparation and use October 13, 2009
Carboxylic acid derivatives ##STR00001## where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
7582647 Carboxylic acid derivatives, their preparation and use September 1, 2009
Carboxylic acid derivatives ##STR00001## where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
7119097 Carboxylic acid derivatives, their preparation and their use October 10, 2006
A compound of the formula ##STR00001## pharmaceutically acceptable salts and enantiomers thereof and pharmaceutical compositions containing this compound, its pharmaceutically acceptable salts and enantiomers are claimed.
7109205 Carboxylic acid derivatives, their preparation and use September 19, 2006
Carboxylic acid derivatives ##STR00001## where R R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
6686369 .alpha.-hydrdroxylic acid derivatives, their production and use February 3, 2004
The present invention relates to carboxylic acid derivatives of the formula ##STR1##where the radicals have the meanings stated in the description, to the preparation of these compounds and to their use as drugs.
6670367 Azinyloxy, and phenoxy-diaryl-carboxylic acid derivatives, their preparation and use as mixed ET December 30, 2003
The invention relates to carboxylic acid derivatives of the formula I ##STR1##where the radicals have the meanings stated in the description, and to their use as drugs.
6600043 Carboxylic acid derivatives, their preparation and use July 29, 2003
Carboxylic acid derivatives ##STR1##where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
6509341 Carboxylic acid derivatives, carrying amido side-chains; production and use as endothelin recept January 21, 2003
The invention relates to carboxylic acid derivatives of formula (I), wherein the substituents have the meaning as commented in the description. It also relates to the production and use of same as endothelin receptor antagonists.
6448248 Heterocyclic carboxylic acid derivatives, the production and use thereof as endothelin receptor September 10, 2002
The present invention relates to carboxylic acid derivatives of the formula I ##STR1##where the substituents have the meanings explained in the description, and to preparation and use as endothelin receptor antagonists.
6440975 Amino acid derivatives, the preparation and use thereof as endothelin antagonists August 27, 2002
The invention relates to amino acid derivatives of the formula I ##STR1##where the radicals have the meanings stated in the description, and to the use thereof as drugs.
6358983 Heterocyclically substituted .alpha.-hydroxycarboxylic acid derivatives, method for producing th March 19, 2002
The present invention relates to carboxylic acid derivatives of the formula I ##STR1##the substituents having the meanings explained in the description, preparation and use as endothelin receptor antagonists.
6197958 Carboxylic acid derivatives, their preparation and use March 6, 2001
Carboxylic acid derivatives ##STR1##where R--R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
6103732 Carboxylic acid derivatives, their production and use August 15, 2000
Carboxylic acid derivatives of the formula I ##STR1## where the radicals have the meanings stated in the description, and the preparation of these agreements [sic] and their use as drugs are described.
6004988 Carboxylic acid derivatives, their preparation and their use December 21, 1999
Carboxylic acid derivatives of the formula I ##STR1## here R.sup.1 is a tetrazole [sic], nitrile [sic], a group COOH or a radical which can be hydrolyzed to COOH, and the other substituents have the meaning explained in the description.
5969134 Carboxylic acid derivatives, their preparation and use October 19, 1999
Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
5932730 Carboxylic acid derivatives, their preparation and use August 3, 1999
Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
5840722 Use of carboxylic acid derivatives as drugs November 24, 1998
A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I ##STR1##
5693637 Bicycle derivatives, their preparation and use December 2, 1997
The description relates to bicyclene derivatives of formula (I) in which A, B, D, E, G, K, L, R.sup.1, R.sup.2, Z.sup.1 and Z.sup.2 have the meanings given in the description, and their production. These compounds are suitable for treating diseases. ##STR1##
5039701 Novel benzofuran derivatives and therapeutic agents containing them August 13, 1991
Benzofuran derivatives of the formula I ##STR1## where R.sup.1 to R.sup.5 and X have the meanings stated in the description, and therapeutic agents containing these derivatives.
4968717 Phenylacetonitriles which are substituted by basic groups, their preparation and drugs containin November 6, 1990
Compounds of the formula ##STR1## where R.sup.1 to R.sup.7, m, n and p have the meanings stated in the description, and certain derivatives which are p-substituted in the left-hand phenyl ring, are useful for the treatment of disorders.
4242332 4,5-Methano-bufadienolide-rhamnosides, their preparation, and drugs containing these compounds December 30, 1980
4,5-methano-bufadienolide-rhamnosides of the formula I ##STR1## where R.sup.1 is hydrogen or alkyl or acyl of 1 to 4 carbon atoms, R.sup.2 and R.sup.3 are identical or different and each is hydrogen or alkyl or acyl of 1 to 4 carbon atoms, or both together are ##STR2## where
4183935 Bispidine derivatives, their preparation, and drugs containing same January 15, 1980
Bispidine derivatives of the formula ##STR1## where R.sup.1 is H or C.sub.6 H.sub.5, R.sup.2 is H, Cl or CF.sub.3, R.sup.3 is H, F or Cl and X is 0 or 1, and drugs which contain these compounds. The compounds are prepared by condensing N-monobenzylbispidine with appropriately sub


 
 
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